COMT genetic reduction produces sexually divergent effects on cortical anatomy and working memory in mice and humans

Cerebral Cortex

Volumn 25, Issue 9, 2015, Pages 2529-2541

  Sannino, Sara ^a   Gozzi, Alessandro ^a   Cerasa, Antonio ^b   Piras, Fabrizio ^c   Scheggia, Diego ^a   Managò, Francesca ^a   Damiano, Mario ^a   Galbusera, Alberto ^a   Erickson, Lucy C ^d   De Pietri Tonelli, Davide ^a   Bifone, Angelo ^a   Tsaftaris, Sotirios A ^e   Caltagirone, Carlo ^c   Weinberger, Daniel R ^f   Spalletta, Gianfranco ^c   Papaleo, Francesco ^a,g  

^a ISTITUTO ITALIANO DI TECNOLOGIA   (Italy)

^b CNR   (Italy)

^c IRCCS FONDAZIONE SANTA LUCIA   (Italy)

^d NATIONAL INSTITUTE OF MENTAL HEALTH   (United States)

^e IMT SCHOOL FOR ADVANCED STUDIES LUCCA   (Italy)

^f JOHNS HOPKINS UNIVERSITY   (United States)

^g UNIVERSITY OF PADOVA   (Italy)

Author keywords

Cognition; Cortical thickness; Dopamine; Postero parietal cortex; Prefrontal cortex

Indexed keywords

CATECHOL METHYLTRANSFERASE; CUTL1 PROTEIN, MOUSE; ENOLASE; HOMEODOMAIN PROTEIN; NUCLEAR PROTEIN; REPRESSOR PROTEIN;

ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BEHAVIOR; BRAIN CORTEX; CONTROLLED STUDY; CORTICAL THICKNESS (BRAIN); CYTOARCHITECTURE; DENSITY; ENZYME ACTIVITY; FEMALE; GENE INTERACTION; GENETIC VARIATION; HUMAN; HUMAN CELL; HUMAN EXPERIMENT; MALE; MORPHOLOGY; MOUSE; NEUROANATOMY; NONHUMAN; OUTCOME ASSESSMENT; POSTERIOR PARIETAL CORTEX; PREFRONTAL CORTEX; PRIORITY JOURNAL; SEX DIFFERENCE; TEMPORAL CORTEX; WORKING MEMORY; ADOLESCENT; ANALYSIS OF VARIANCE; ANATOMY AND HISTOLOGY; ANIMAL; BRAIN MAPPING; CYTOLOGY; DEFICIENCY; GENETICS; GENOTYPE; LEARNING; MAZE TEST; METABOLISM; MIDDLE AGED; MUTATION; NERVE CELL; NUCLEAR MAGNETIC RESONANCE IMAGING; PHYSIOLOGY; SEXUAL DEVELOPMENT; SHORT TERM MEMORY; TRANSGENIC MOUSE; YOUNG ADULT;

ADOLESCENT; ADULT; ANALYSIS OF VARIANCE; ANIMALS; ASSOCIATION LEARNING; BRAIN MAPPING; CATECHOL O-METHYLTRANSFERASE; CEREBRAL CORTEX; FEMALE; GENOTYPE; HOMEODOMAIN PROTEINS; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MAZE LEARNING; MEMORY, SHORT-TERM; MICE; MICE, TRANSGENIC; MIDDLE AGED; MUTATION; NEURONS; NUCLEAR PROTEINS; PHOSPHOPYRUVATE HYDRATASE; REPRESSOR PROTEINS; SEX CHARACTERISTICS; YOUNG ADULT;

EID: 84964600257     PISSN: 10473211     EISSN: 14602199     Source Type: Journal    
DOI: 10.1093/cercor/bhu053     Document Type: Article

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