Biological effects of COMT haplotypes and psychosis risk in 22q11.2 deletion syndrome

Biological Psychiatry

Volumn 75, Issue 5, 2014, Pages 406-413

  Gothelf, Doron ^a,b   Law, Amanda J ^c,d   Frisch, Amos ^b   Chen, Jingshan ^d   Zarchi, Omer ^a,b   Michaelovsky, Elena ^b   Ren Patterson, Renee ^d   Lipska, Barbara K ^d   Carmel, Miri ^b   Kolachana, Bhaskar ^d   Weizman, Abraham ^b   Weinberger, Daniel R ^d,e,f  

^a SHEBA MEDICAL CENTER   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

^e JOHNS HOPKINS UNIVERSITY   (United States)

^f JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

COMT; DiGeorge; gene expression; haplotype; psychosis; velocardiofacial syndrome

Indexed keywords

CATECHOL METHYLTRANSFERASE; MESSENGER RNA;

3' UNTRANSLATED REGION; ADULT; ARTICLE; CHROMOSOME DELETION 22Q11; COGNITIVE DEFECT; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME ASSAY; FEMALE; GENE DELETION; GENE EXPRESSION PROFILING; GENETIC RISK; GENETIC VARIABILITY; GENOTYPE PHENOTYPE CORRELATION; HAPLOTYPE; HEMIZYGOSITY; HUMAN; HUMAN CELL; INTELLIGENCE QUOTIENT; LYMPHOBLAST; MAJOR CLINICAL STUDY; MALE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PSYCHOSIS; SCHIZOPHRENIA; SINGLE NUCLEOTIDE POLYMORPHISM; SYMPTOMATOLOGY;

COMT; DIGEORGE; GENE EXPRESSION; HAPLOTYPE; PSYCHOSIS; VELOCARDIOFACIAL SYNDROME;

ADOLESCENT; ADULT; CATECHOL O-METHYLTRANSFERASE; CHI-SQUARE DISTRIBUTION; CHILD; CHROMOSOME DELETION; DIGEORGE SYNDROME; FEMALE; GENETIC PREDISPOSITION TO DISEASE; HAPLOTYPES; HUMANS; MALE; METHIONINE; PSYCHIATRIC STATUS RATING SCALES; PSYCHOTIC DISORDERS; VALINE; YOUNG ADULT;

EID: 84893497928     PISSN: 00063223     EISSN: 18732402     Source Type: Journal    
DOI: 10.1016/j.biopsych.2013.07.021     Document Type: Article

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