X-ray structures and mechanism of the human serotonin transporter

Nature

Volumn 532, Issue 7599, 2016, Pages 334-339

  Coleman, Jonathan A ^a   Green, Evan M ^a,b   Gouaux, Eric ^a  

^a OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CITALOPRAM; MAZINDOL; PAROXETINE; SEROTONIN TRANSPORTER; ANTIDEPRESSANT AGENT; DOPAMINE TRANSPORTER; IMMUNOGLOBULIN F(AB) FRAGMENT; ION; LIGAND; PROTEIN BINDING; SEROTONIN;

BIOTECHNOLOGY; CELLS AND CELL COMPONENTS; CHLORIDE; DESIGN; DRUG; LIGAND; PROTEIN; SODIUM; X-RAY;

ALLOSTERISM; ARTICLE; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATION; CRYSTAL STRUCTURE; HUMAN; MOLECULAR RECOGNITION; PRIORITY JOURNAL; VESTIBULE; X RAY CRYSTALLOGRAPHY; CHEMICAL STRUCTURE; CHEMISTRY; DRUG DESIGN; DRUG EFFECTS; EXTRACELLULAR SPACE; IMMUNOLOGY; INTRACELLULAR SPACE; METABOLISM; PROTEIN CONFORMATION; PROTEIN STABILITY; STRUCTURE ACTIVITY RELATION;

ALLOSTERIC REGULATION; ALLOSTERIC SITE; ANTIDEPRESSIVE AGENTS; CITALOPRAM; CRYSTALLOGRAPHY, X-RAY; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; DRUG DESIGN; EXTRACELLULAR SPACE; HUMANS; IMMUNOGLOBULIN FAB FRAGMENTS; INTRACELLULAR SPACE; IONS; LIGANDS; MODELS, MOLECULAR; PAROXETINE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STABILITY; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84964498770     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature17629     Document Type: Article

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