Conformational dynamics of ligand-dependent alternating access in LeuT

Nature Structural and Molecular Biology

Volumn 21, Issue 5, 2014, Pages 472-479

  Kazmier, Kelli ^a   Sharma, Shruti ^b   Quick, Matthias ^c,d   Islam, Shahidul M ^e   Roux, Benoît ^e   Weinstein, Harel ^f   Javitch, Jonathan A ^c,d   McHaourab, Hassane S ^a,b  

^a VANDERBILT UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Department of Molecular Physiology and Biophysics ^*  (United States)

^c Center for Molecular Recognition Columbia University College of Physicians and Surgeons ^*  (United States)

^d NEW YORK STATE PSYCHIATRIC INSTITUTE   (United States)

^e UNIVERSITY OF CHICAGO   (United States)

^f WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LEUCINE; LIGAND; NEUROTRANSMITTER; SODIUM IODIDE SYMPORTER; SODIUM ION; LEUCINE TRANSPORTER; SODIUM; UNCLASSIFIED DRUG;

AQUIFEX AEOLICUS; ARTICLE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; ISOMERIZATION; MUTANT; NONHUMAN; PRIORITY JOURNAL; PROTEIN MOTIF; SPIN LABELING; WILD TYPE; ELECTRON SPIN RESONANCE; INTRACELLULAR TRANSPORT; MUTATION;

AQUIFEX AEOLICUS; BACTERIA (MICROORGANISMS);

BACTERIAL PROTEINS; LIGANDS; MODELS, MOLECULAR; NEUROTRANSMITTER TRANSPORT PROTEINS; PROTEIN STRUCTURE, TERTIARY; SPIN LABELS; SYMPORTERS;

EID: 84902085088     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2816     Document Type: Article

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