Evaluation of a glycoengineered monoclonal antibody via LC-MS analysis in combination with multiple enzymatic digestion

mAbs

Volumn 8, Issue 2, 2016, Pages 340-346

  Liu, Renpeng ^a   Giddens, John ^b   McClung, Colleen M ^a   Magnelli, Paula E ^a   Wang, Lai Xi ^b   Guthrie, Ellen P ^a  

^a NEW ENGLAND BIOLABS   (United States)

^b Bldg 142   (United States)

Author keywords

Antibody characterization; Glycoengineering; Glycosylation analysis; LC MS; Procainamide

Indexed keywords

2 AMINOBENZAMIDE; ASPARAGINE; DISULFIDE; PROCAINAMIDE; RITUXIMAB; SIALIC ACID; N ACETYLNEURAMINIC ACID;

ARTICLE; CHEMICAL MODIFICATION; COMPARATIVE STUDY; ENZYME MODIFICATION; GLYCOSYLATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROPHILIC INTERACTION CHROMATOGRAPHY; ION CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; PROTEIN PROCESSING; SENSITIVITY ANALYSIS; SENSITIVITY AND SPECIFICITY; ANIMAL; CHEMISTRY; CHO CELL LINE; CRICETULUS; HAMSTER; HUMAN;

ANIMALS; CHO CELLS; CRICETINAE; CRICETULUS; GLYCOSYLATION; HUMANS; MASS SPECTROMETRY; N-ACETYLNEURAMINIC ACID; RITUXIMAB;

EID: 84964411843     PISSN: 19420862     EISSN: 19420870     Source Type: Journal    
DOI: 10.1080/19420862.2015.1113361     Document Type: Article

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