Patatin-like phospholipase domain-containing 3 (PNPLA3) I148M (rs738409) affects hepatic VLDL secretion in humans and in vitro

Journal of Hepatology

Volumn 57, Issue 6, 2012, Pages 1276-1282

  Pirazzi, Carlo ^a   Adiels, Martin ^a,b   Burza, Maria Antonella ^a   Mancina, Rosellina Margherita ^a,c   Levin, Malin ^a   Ståhlman, Marcus ^a   Taskinen, Marja Riitta ^d   Orho Melander, Marju ^e   Perman, Jeanna ^a   Pujia, Arturo ^c   Andersson, Linda ^a   Maglio, Cristina ^a   Montalcini, Tiziana ^c   Wiklund, Olov ^a   Borén, Jan ^a   Romeo, Stefano ^a,c  

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b UNIVERSITY OF GOTHENBURG   (Sweden)

^c UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^d UNIVERSITY OF HELSINKI   (Finland)

^e LUND UNIVERSITY   (Sweden)

Author keywords

Apolipoprotein B; Genetic variant; Lipolysis; Liver fat content; Patatin like phospholipase domain containing 3; VLDL secretion

Indexed keywords

APOLIPOPROTEIN B100; GLYCEROLIPID; MUTANT PROTEIN; PATATIN LIKE PHOSPHOLIPASE DOMAIN CONTAINING 3; PHOSPHOLIPASE; TRIACYLGLYCEROL; UNCLASSIFIED DRUG; VERY LOW DENSITY LIPOPROTEIN;

ADULT; ANIMAL CELL; ARTICLE; CELL LEVEL; CONTROLLED STUDY; GENE MUTATION; GENE OVEREXPRESSION; GENETIC VARIABILITY; GENOTYPE; HETEROZYGOTE; HOMOZYGOTE; HUMAN; IN VITRO STUDY; KINETICS; LIPID METABOLISM; LOSS OF FUNCTION MUTATION; MAJOR CLINICAL STUDY; MALE; NONALCOHOLIC FATTY LIVER; NONHUMAN; OBESITY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN LOCALIZATION; PROTEIN SECRETION; RAT; WILD TYPE;

ADULT; ANIMALS; APOLIPOPROTEINS B; CELLS, CULTURED; GENOTYPE; HUMANS; LIPASE; LIPID METABOLISM; LIPOPROTEINS, VLDL; LIVER; MEMBRANE PROTEINS; MIDDLE AGED; RATS;

EID: 84869224701     PISSN: 01688278     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jhep.2012.07.030     Document Type: Article

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