Metastasized lung cancer suppression by Morinda citrifolia (Noni) leaf compared to Erlotinib via anti-inflammatory, endogenous antioxidant responses and apoptotic gene activation

Molecular and Cellular Biochemistry

Volumn 416, Issue 1-2, 2016, Pages 85-97

  Lim, Swee Ling ^a   Mustapha, Noordin M ^a   Goh, Yong Meng ^a   Bakar, Nurul Ain Abu ^a   Mohamed, Suhaila ^a  

^a UNIVERSITY PUTRA MALAYSIA   (Malaysia)

Author keywords

BCL2; Differential counts; IL10; IL4; NFE2L2; NR3C1; TRP53

Indexed keywords

BIRC5 PROTEIN; CASPASE 3; CASPASE 8; CASPASE 9; ERLOTINIB; INTERLEUKIN 10; INTERLEUKIN 4; JANUS KINASE 2; MORINDA CITRIFOLIA EXTRACT; NR3C1 PROTEIN; STAT3 PROTEIN; STAT5A PROTEIN; TRP53 PROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG; ANTIINFLAMMATORY AGENT; ANTIOXIDANT; PLANT EXTRACT;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ANTIOXIDANT ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CONTROLLED STUDY; CYTOTOXICITY TEST; DRUG APPROVAL; FOOD AND DRUG ADMINISTRATION; G1 PHASE CELL CYCLE CHECKPOINT; GENE ACTIVATION; HUMAN; HUMAN CELL; IC50; IN VITRO STUDY; IN VIVO STUDY; LIVER CANCER; LUNG CANCER; LUNG PARENCHYMA; MOUSE; NONHUMAN; PLANT LEAF; ANIMAL; BAGG ALBINO MOUSE; CHEMISTRY; COMPARATIVE STUDY; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; LUNG NEOPLASMS; MALE; METABOLISM; METASTASIS; MORINDA; PATHOLOGY; TUMOR CELL LINE;

ANIMALS; ANTI-INFLAMMATORY AGENTS; ANTIOXIDANTS; APOPTOSIS; CELL LINE, TUMOR; ERLOTINIB HYDROCHLORIDE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LUNG NEOPLASMS; MALE; MICE; MICE, INBRED BALB C; MORINDA; NEOPLASM METASTASIS; PLANT EXTRACTS; PLANT LEAVES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84964301457     PISSN: 03008177     EISSN: 15734919     Source Type: Journal    
DOI: 10.1007/s11010-016-2698-x     Document Type: Article

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