Persistence of epidermal growth factor receptor and interleukin 10 in blood of colorectal cancer patients after surgery identifies patients with high risk to relapse

Clinical Cancer Research

Volumn 9, Issue 7, 2003, Pages 2678-2682

  Giacomelli, Luciano ^a   Gianni, Walter ^b   Belfiore, Cristiano ^a   Gandini, Orietta ^c   Repetto, Lazzaro ^b,c   Filippini, Angelo ^a   Frati, Luigi ^c   Aglianò, Anna Maria ^c   Gazzaniga, Paola ^c  

^a POLICLINICO UMBERTO I   (Italy)

^b INRCA   (Italy)

^c SAPIENZA UNIVERSITY OF ROME   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

EPIDERMAL GROWTH FACTOR RECEPTOR; INTERLEUKIN 10; INTERLEUKIN 6; MESSENGER RNA;

ADULT; AGED; ARTICLE; BLOOD SAMPLING; CANCER GROWTH; CANCER PATIENT; CANCER RECURRENCE; CANCER RISK; CANCER SURGERY; COLORECTAL CANCER; CONTROLLED STUDY; CORRELATION ANALYSIS; DISEASE COURSE; DISEASE SEVERITY; EVALUATION; FEMALE; FOLLOW UP; GENE EXPRESSION; HUMAN; MAJOR CLINICAL STUDY; MALE; PREDICTION; PREOPERATIVE EVALUATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN BLOOD LEVEL; PROTEIN EXPRESSION; RECURRENCE RISK; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RISK ASSESSMENT;

ACTINS; COLORECTAL NEOPLASMS; DISEASE-FREE SURVIVAL; FEMALE; HELA CELLS; HUMANS; INTERLEUKIN-10; INTERLEUKIN-6; MALE; RECEPTOR, EPIDERMAL GROWTH FACTOR; RECURRENCE; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RISK; TIME FACTORS;

EID: 0038493554     PISSN: 10780432     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (10)

1. Ghossein, R. A., and Bhattacharya, S. Molecular detection and characterisation of circulating tumour cells and micrometastases in solid tumours. Eur. J. Cancer, 36: 1681-1694, 2000.
2. Wong, I. H. N., Yeo, W., Chan, A. T., and Johnson, P. J. Quantitative relationship of the circulating tumor burden assessed by reverse transcription-polymerase chain reaction for cytokeratin 19 mRNA in peripheral blood of colorectal cancer patients with Dukes' stage, serum carcinoembryonic antigen level and tumor progression. Cancer Lett., 162: 65-73, 2001.
3. Bustin, S. A., Gyselman, V. G., Williams, N. S., and Dorudi, S. Detection of cytokeratins 19/20 and guanylyi cyclase C in peripheral blood of colorectal cancer patients. Br. J. Cancer, 79: 1813-1820, 1999.
4. Douard, R., Le Maire, V., Wind, P., Sales, J. P., Dumas, F., Fayemendi, L., Landi, B., Benichou, J., Cugnenc, P. H., Gayral, F., Loric, S., et al. Carcinoembryonic gene number 2 mRNA expression as a marker to detect circulating enterocytes in the blood of colorectal cancer patients. Surgery (St. Louis). 129: 587-594, 2001.
5. De Luca, A., Pignata, S., Casamassimi, A., D'Antonio, A., Gridelli, C., Rossi, A., Cremona, F., Parisi, V., De Matteis, A., and Normanno, N. Detection of circulating tumor cells in carcinoma patients by a novel epidermal growth factor receptor reverse transcription-PCR assay. Clin. Cancer Res., 6: 1439-1444, 2000.
6. Gazzaniga, P., Gandini, O., Giuliani, L., Magnanti, M., Gradilone, A., Silvestri, I., Gianni, W., Gallucci, M., Frati, L., and Aglianò, A. M. Detection of epidermal growth factor receptor mRNA in peripheral blood: a new marker of circulating neoplastic cells in bladder cancer patients. Clin. Cancer Res., 7: 577-583, 2001.
7. Gazzaniga, P., Gradilone, A., Frati, L., and Aglianò, A. M. Epidermal growth factor receptor (EGFR) mRNA expression in peripheral blood of bladder cancer patients: a potential marker to detect treatment failure. Clin. Cancer Res., 7: 4288-4289, 2001.
8. Galizia, G., Orditura, M., Romano, C., Lieto, E., Castellano, P., Pelosio, L., Imperatore, V., Catalano, G., Pignatelli, C., and De Vita, F. Prognostic significance of circulating IL-10 and IL-6 serum levels in colon cancer patients undergoing surgery. Clin. Immunol., 102: 169-178, 2002.
9. De Vita, F., Orditura, M., Galizia, G., Romano, C., Infusino, S., Auriemma, A., Lieto, E., Catalano, G., et al. Serum interleukin-10 levels in patients with advanced gastrointestinal malignancies. Cancer (Phila.), 86: 1936-1943, 1999.
10. Fortis, C., Foppoli, M., Gianotti, L., Galli. L., Citterio, G., Consogno, G., Gentilini, O., Braga, M., et al. Increased interleukin 10 serum levels in patients with solid tumors. Cancer Lett., 104: 1-5, 1996.