Glucose and glutamine fuel protein O-GlcNAcylation to control T cell self-renewal and malignancy

Nature Immunology

Volumn 17, Issue 6, 2016, Pages 712-720

  Swamy, Mahima ^a   Pathak, Shalini ^a   Grzes, Katarzyna M ^a   Damerow, Sebastian ^a   Sinclair, Linda V ^a   Van Aalten, Daan M F ^a   Cantrell, Doreen A ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; GLUTAMINE; GLYCOSYLTRANSFERASE; INTERLEUKIN 2; MYC PROTEIN; N ACETYLGLUCOSAMINE; NOTCH RECEPTOR; T LYMPHOCYTE RECEPTOR; URIDINE DIPHOSPHATE N ACETYLGALACTOSAMINE; URIDINE DIPHOSPHATE N ACETYLGLUCOSAMINE; LYMPHOCYTE ANTIGEN RECEPTOR; MYC PROTEIN, MOUSE; N ACETYLGLUCOSAMINYLTRANSFERASE; PROTEIN KINASE LCK;

ACYLATION; AMINO ACID TRANSPORT; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BONE MARROW STROMA CELL; CD4 LYMPHOCYTE COUNT; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL SELF-RENEWAL; CELL SIZE; CONTROLLED STUDY; CYTOTOXIC T LYMPHOCYTE; EFFECTOR CELL; FEMALE; GLUCOSE METABOLISM; GLUCOSE TRANSPORT; LISTERIOSIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE TRANSFORMATION; MALE; MALIGNANT TRANSFORMATION; MOUSE; NONHUMAN; NUTRIENT UPTAKE; PRE T LYMPHOCYTE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; SPLEEN CELL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMOCYTE; ANIMAL; C57BL MOUSE; CELL CLONE; CELL PROLIFERATION; CELL TRANSFORMATION; GENETICS; KNOCKOUT MOUSE; LYMPHOCYTE ACTIVATION; METABOLISM; PHYSIOLOGY;

ANIMALS; CELL PROLIFERATION; CELL SELF RENEWAL; CELL TRANSFORMATION, NEOPLASTIC; CLONE CELLS; FEMALE; GLUCOSE; GLUTAMINE; LYMPHOCYTE ACTIVATION; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; N-ACETYLGLUCOSAMINYLTRANSFERASES; PROTO-ONCOGENE PROTEINS C-MYC; RECEPTORS, ANTIGEN, T-CELL; RECEPTORS, NOTCH; T-LYMPHOCYTES; URIDINE DIPHOSPHATE N-ACETYLGLUCOSAMINE;

EID: 84964265506     PISSN: 15292908     EISSN: 15292916     Source Type: Journal    
DOI: 10.1038/ni.3439     Document Type: Article

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