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Volumn 20, Issue 1, 2016, Pages

Sepsis-induced long-term immune paralysis - results of a descriptive, explorative study

Author keywords

Immune system; Immunocompromised; Immunology; Sepsis

Indexed keywords

B T LYMPHOCYTE ATTENUATOR; CD28 ANTIGEN; CD3 ANTIGEN; CELL SURFACE RECEPTOR; DECTIN 1; GAMMA INTERFERON; HLA DR ANTIGEN; INTERLEUKIN 10; INTERLEUKIN 6; LIPOPOLYSACCHARIDE; PROGRAMMED DEATH 1 LIGAND 1; PROGRAMMED DEATH 1 RECEPTOR; TOLL LIKE RECEPTOR 2; TOLL LIKE RECEPTOR 4; TOLL LIKE RECEPTOR 5; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; ZYMOSAN; LECTIN;

EID: 84963768824     PISSN: 13648535     EISSN: 1466609X     Source Type: Journal    
DOI: 10.1186/s13054-016-1233-5     Document Type: Article
Times cited : (90)

References (39)
  • 1
    • 0034958947 scopus 로고    scopus 로고
    • Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care
    • Angus DC, Linde-Zwirble WT, Lidicker J, Clermont G, Carcillo J, Pinsky MR. Epidemiology of severe sepsis in the United States: analysis of incidence, outcome, and associated costs of care. Crit Care Med. 2001;29:1303-10.
    • (2001) Crit Care Med. , vol.29 , pp. 1303-1310
    • Angus, D.C.1    Linde-Zwirble, W.T.2    Lidicker, J.3    Clermont, G.4    Carcillo, J.5    Pinsky, M.R.6
  • 4
    • 0026710191 scopus 로고
    • Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine
    • Bone RC, Balk RA, Cerra FB, Dellinger RP, Fein AM, Knaus WA, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. American College of Chest Physicians/Society of Critical Care Medicine. Chest. 1992;101:1644-55.
    • (1992) Chest , vol.101 , pp. 1644-1655
    • Bone, R.C.1    Balk, R.A.2    Cerra, F.B.3    Dellinger, R.P.4    Fein, A.M.5    Knaus, W.A.6
  • 5
    • 0030843156 scopus 로고    scopus 로고
    • Sepsis: a new hypothesis for pathogenesis of the disease process
    • Bone RC, Grodzin CJ, Balk RA. Sepsis: a new hypothesis for pathogenesis of the disease process. Chest. 1997;112:235-43.
    • (1997) Chest. , vol.112 , pp. 235-243
    • Bone, R.C.1    Grodzin, C.J.2    Balk, R.A.3
  • 6
    • 0030011909 scopus 로고    scopus 로고
    • Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation
    • Bone RC. Toward a theory regarding the pathogenesis of the systemic inflammatory response syndrome: what we do and do not know about cytokine regulation. Crit Care Med. 1996;24:163-72.
    • (1996) Crit Care Med. , vol.24 , pp. 163-172
    • Bone, R.C.1
  • 8
    • 33750288937 scopus 로고    scopus 로고
    • Apoptosis and caspases regulate death and inflammation in sepsis
    • Hotchkiss RS, Nicholson DW. Apoptosis and caspases regulate death and inflammation in sepsis. Nat Rev Immunol. 2006;6:813-22.
    • (2006) Nat Rev Immunol. , vol.6 , pp. 813-822
    • Hotchkiss, R.S.1    Nicholson, D.W.2
  • 9
    • 0041365362 scopus 로고    scopus 로고
    • Marked elevation of human circulating CD4 + CD25+ regulatory T cells in sepsis-induced immunoparalysis
    • Monneret G, Debard A-L, Venet F, Bohe J, Hequet O, Bienvenu J, et al. Marked elevation of human circulating CD4 + CD25+ regulatory T cells in sepsis-induced immunoparalysis. Crit Care Med. 2003;31:2068-71.
    • (2003) Crit Care Med. , vol.31 , pp. 2068-2071
    • Monneret, G.1    Debard, A.-L.2    Venet, F.3    Bohe, J.4    Hequet, O.5    Bienvenu, J.6
  • 10
    • 84891645973 scopus 로고    scopus 로고
    • The changing immune system in sepsis: is individualized immuno-modulatory therapy the answer?
    • Boomer JS, Green JM, Hotchkiss RS. The changing immune system in sepsis: is individualized immuno-modulatory therapy the answer? Virulence. 2014;5:45-56.
    • (2014) Virulence. , vol.5 , pp. 45-56
    • Boomer, J.S.1    Green, J.M.2    Hotchkiss, R.S.3
  • 11
    • 79960653221 scopus 로고    scopus 로고
    • The late phase of sepsis is characterized by an increased microbiological burden and death rate
    • Otto GP, Sossdorf M, Claus RA, Rödel J, Menge K, Reinhart K, et al. The late phase of sepsis is characterized by an increased microbiological burden and death rate. Crit Care. 2011;15:R183.
    • (2011) Crit Care. , vol.15 , pp. R183
    • Otto, G.P.1    Sossdorf, M.2    Claus, R.A.3    Rödel, J.4    Menge, K.5    Reinhart, K.6
  • 12
    • 79952668917 scopus 로고    scopus 로고
    • ICU-acquired immunosuppression and the risk for secondary fungal infections
    • Monneret G, Venet F, Kullberg B-J, Netea MG. ICU-acquired immunosuppression and the risk for secondary fungal infections. Med Mycol. 2011;49 Suppl 1:S17-23.
    • (2011) Med Mycol. , vol.49 , pp. S17-23
    • Monneret, G.1    Venet, F.2    Kullberg, B.-J.3    Netea, M.G.4
  • 13
    • 84863988959 scopus 로고    scopus 로고
    • Viral infections in septic shock (VISS-trial)-crosslinks between inflammation and immunosuppression
    • Brenner T, Rosenhagen C, Hornig I, Schmidt K, Lichtenstern C, Mieth M, et al. Viral infections in septic shock (VISS-trial)-crosslinks between inflammation and immunosuppression. J Surg Res. 2012;176:571-82.
    • (2012) J Surg Res. , vol.176 , pp. 571-582
    • Brenner, T.1    Rosenhagen, C.2    Hornig, I.3    Schmidt, K.4    Lichtenstern, C.5    Mieth, M.6
  • 14
    • 84873339299 scopus 로고    scopus 로고
    • Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012
    • Dellinger RP, Levy MM, Rhodes A, Annane D, Gerlach H, Opal SM, et al. Surviving Sepsis Campaign: International Guidelines for Management of Severe Sepsis and Septic Shock: 2012. Crit Care Med. 2013;41:580-637.
    • (2013) Crit Care Med. , vol.41 , pp. 580-637
    • Dellinger, R.P.1    Levy, M.M.2    Rhodes, A.3    Annane, D.4    Gerlach, H.5    Opal, S.M.6
  • 15
    • 84255194001 scopus 로고    scopus 로고
    • Immunosuppression in patients who die of sepsis and multiple organ failure
    • Boomer JS, To K, Chang KC, Takasu O, Osborne DF, Walton AH, et al. Immunosuppression in patients who die of sepsis and multiple organ failure. JAMA. 2011;306:2594-605.
    • (2011) JAMA. , vol.306 , pp. 2594-2605
    • Boomer, J.S.1    To, K.2    Chang, K.C.3    Takasu, O.4    Osborne, D.F.5    Walton, A.H.6
  • 16
    • 84864545901 scopus 로고    scopus 로고
    • Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care
    • Gentile LF, Cuenca AG, Efron PA, Ang D, Bihorac A, McKinley BA, et al. Persistent inflammation and immunosuppression: a common syndrome and new horizon for surgical intensive care. J Trauma Acute Care Surg. 2012;72:1491-501.
    • (2012) J Trauma Acute Care Surg. , vol.72 , pp. 1491-1501
    • Gentile, L.F.1    Cuenca, A.G.2    Efron, P.A.3    Ang, D.4    Bihorac, A.5    McKinley, B.A.6
  • 18
    • 0031003777 scopus 로고    scopus 로고
    • Magnitude and duration of the effect of sepsis on survival. Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group
    • Quartin AA, Schein RM, Kett DH, Peduzzi PN. Magnitude and duration of the effect of sepsis on survival. Department of Veterans Affairs Systemic Sepsis Cooperative Studies Group. JAMA. 1997;277:1058-63.
    • (1997) JAMA , vol.277 , pp. 1058-1063
    • Quartin, A.A.1    Schein, R.M.2    Kett, D.H.3    Peduzzi, P.N.4
  • 21
    • 0042832200 scopus 로고    scopus 로고
    • Long-term mortality and medical care charges in patients with severe sepsis
    • Weycker D, Akhras KS, Edelsberg J, Angus DC, Oster G. Long-term mortality and medical care charges in patients with severe sepsis. Crit Care Med. 2003;31:2316-23.
    • (2003) Crit Care Med. , vol.31 , pp. 2316-2323
    • Weycker, D.1    Akhras, K.S.2    Edelsberg, J.3    Angus, D.C.4    Oster, G.5
  • 22
    • 79952378225 scopus 로고    scopus 로고
    • Epigenetic regulation of immune cell functions during post-septic immunosuppression
    • Carson WF, Cavassani KA, Dou Y, Kunkel SL. Epigenetic regulation of immune cell functions during post-septic immunosuppression. Epigenetics. 2011;6:273-83.
    • (2011) Epigenetics. , vol.6 , pp. 273-283
    • Carson, W.F.1    Cavassani, K.A.2    Dou, Y.3    Kunkel, S.L.4
  • 23
    • 84919922592 scopus 로고    scopus 로고
    • Immunosuppression after sepsis: systemic inflammation and sepsis induce a loss of naïve T-cells but no enduring cell-autonomous defects in T-cell function
    • Markwart R, Condotta SA, Requardt RP, Borken F, Schubert K, Weigel C, et al. Immunosuppression after sepsis: systemic inflammation and sepsis induce a loss of naïve T-cells but no enduring cell-autonomous defects in T-cell function. PLoS One. 2014;9:e115094.
    • (2014) PLoS One. , vol.9 , pp. e115094
    • Markwart, R.1    Condotta, S.A.2    Requardt, R.P.3    Borken, F.4    Schubert, K.5    Weigel, C.6
  • 24
    • 84932102281 scopus 로고    scopus 로고
    • Polymicrobial Sepsis Increases Susceptibility to Chronic Viral Infection and Exacerbates CD8+ T Cell Exhaustion
    • Condotta SA, Khan SH, Rai D, Griffith TS, Badovinac VP. Polymicrobial Sepsis Increases Susceptibility to Chronic Viral Infection and Exacerbates CD8+ T Cell Exhaustion. J Immunol. 2015;195:116-25.
    • (2015) J Immunol. , vol.195 , pp. 116-125
    • Condotta, S.A.1    Khan, S.H.2    Rai, D.3    Griffith, T.S.4    Badovinac, V.P.5
  • 25
    • 84925610553 scopus 로고    scopus 로고
    • Sepsis induces specific changes in histone modification patterns in human monocytes
    • Weiterer S, Uhle F, Lichtenstern C, Siegler BH, Bhuju S, Jarek M, et al. Sepsis induces specific changes in histone modification patterns in human monocytes. PLoS One. 2015;10:e0121748.
    • (2015) PLoS One. , vol.10 , pp. e0121748
    • Weiterer, S.1    Uhle, F.2    Lichtenstern, C.3    Siegler, B.H.4    Bhuju, S.5    Jarek, M.6
  • 26
    • 84938994763 scopus 로고    scopus 로고
    • Does prior sepsis alter subsequent circadian and sickness behaviour response to lipopolysaccharide treatment in mice?
    • Anderson ST, O'Callaghan EK, Commins S, Coogan AN. Does prior sepsis alter subsequent circadian and sickness behaviour response to lipopolysaccharide treatment in mice? J Neural Transm. 2015;122(Suppl):S63-73.
    • (2015) J Neural Transm , vol.122 , pp. S63-73
    • Anderson, S.T.1    O'Callaghan, E.K.2    Commins, S.3    Coogan, A.N.4
  • 27
    • 84919423676 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse
    • Anderson ST, Commins S, Moynagh PN, Coogan AN. Lipopolysaccharide-induced sepsis induces long-lasting affective changes in the mouse. Brain Behav Immun. 2015;43:98-109.
    • (2015) Brain Behav Immun. , vol.43 , pp. 98-109
    • Anderson, S.T.1    Commins, S.2    Moynagh, P.N.3    Coogan, A.N.4
  • 29
    • 33748317968 scopus 로고    scopus 로고
    • Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M
    • Deng JC. Sepsis-induced suppression of lung innate immunity is mediated by IRAK-M. J Clin Invest. 2006;116:2532-42.
    • (2006) J Clin Invest. , vol.116 , pp. 2532-2542
    • Deng, J.C.1
  • 31
    • 84862766869 scopus 로고    scopus 로고
    • A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis
    • Boomer JS, Shuherk-Shaffer J, Hotchkiss RS, Green JM. A prospective analysis of lymphocyte phenotype and function over the course of acute sepsis. Crit Care. 2012;16:R112.
    • (2012) Crit Care. , vol.16 , pp. R112
    • Boomer, J.S.1    Shuherk-Shaffer, J.2    Hotchkiss, R.S.3    Green, J.M.4
  • 32
    • 79951947339 scopus 로고    scopus 로고
    • Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients
    • Zhang Y, Li J, Lou J, Zhou Y, Bo L, Zhu J, et al. Upregulation of programmed death-1 on T cells and programmed death ligand-1 on monocytes in septic shock patients. Crit Care. 2011;15:R70.
    • (2011) Crit Care. , vol.15 , pp. R70
    • Zhang, Y.1    Li, J.2    Lou, J.3    Zhou, Y.4    Bo, L.5    Zhu, J.6
  • 33
    • 84877262213 scopus 로고    scopus 로고
    • Blockade of the negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis
    • Chang KC, Burnham C-A, Compton SM, Rasche DP, Mazuski R, McDonough JS, et al. Blockade of the negative co-stimulatory molecules PD-1 and CTLA-4 improves survival in primary and secondary fungal sepsis. Crit Care. 2013;17:R85.
    • (2013) Crit Care. , vol.17 , pp. R85
    • Chang, K.C.1    Burnham, C.-A.2    Compton, S.M.3    Rasche, D.P.4    Mazuski, R.5    McDonough, J.S.6
  • 34
    • 40349091729 scopus 로고    scopus 로고
    • Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony
    • Monneret G, Venet F, Pachot A, Lepape A. Monitoring immune dysfunctions in the septic patient: a new skin for the old ceremony. Mol Med. 2008;14:64-78.
    • (2008) Mol Med. , vol.14 , pp. 64-78
    • Monneret, G.1    Venet, F.2    Pachot, A.3    Lepape, A.4
  • 35
    • 33747156889 scopus 로고    scopus 로고
    • Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock
    • Monneret G, Lepape A, Voirin N, Bohé J, Venet F, Debard A-L, et al. Persisting low monocyte human leukocyte antigen-DR expression predicts mortality in septic shock. Intensive Care Med. 2006;32:1175-83.
    • (2006) Intensive Care Med. , vol.32 , pp. 1175-1183
    • Monneret, G.1    Lepape, A.2    Voirin, N.3    Bohé, J.4    Venet, F.5    Debard, A.-L.6
  • 36
    • 78349287748 scopus 로고    scopus 로고
    • Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma
    • Cheron A, Floccard B, Allaouchiche B, Guignant C, Poitevin F, Malcus C, et al. Lack of recovery in monocyte human leukocyte antigen-DR expression is independently associated with the development of sepsis after major trauma. Crit Care. 2010;14:R208.
    • (2010) Crit Care. , vol.14 , pp. R208
    • Cheron, A.1    Floccard, B.2    Allaouchiche, B.3    Guignant, C.4    Poitevin, F.5    Malcus, C.6
  • 37
    • 78650419440 scopus 로고    scopus 로고
    • Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock
    • Landelle C, Lepape A, Voirin N, Tognet E, Venet F, Bohé J, et al. Low monocyte human leukocyte antigen-DR is independently associated with nosocomial infections after septic shock. Intensive Care Med. 2010;36:1859-66.
    • (2010) Intensive Care Med. , vol.36 , pp. 1859-1866
    • Landelle, C.1    Lepape, A.2    Voirin, N.3    Tognet, E.4    Venet, F.5    Bohé, J.6
  • 38
    • 70349653291 scopus 로고    scopus 로고
    • Monocytic HLA-DR expression in intensive care patients: interest for prognosis and secondary infection prediction
    • Lukaszewicz A-C, Grienay M, Resche-Rigon M, Pirracchio R, Faivre V, Boval B, et al. Monocytic HLA-DR expression in intensive care patients: interest for prognosis and secondary infection prediction. Crit Care Med. 2009;37:2746-52.
    • (2009) Crit Care Med. , vol.37 , pp. 2746-2752
    • Lukaszewicz, A.-C.1    Grienay, M.2    Resche-Rigon, M.3    Pirracchio, R.4    Faivre, V.5    Boval, B.6


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