Interleukin-34 induces Cc-chemokine ligand 20 in gut epithelial cells

Journal of Crohn's and Colitis

Volumn 10, Issue 1, 2016, Pages 87-94

  Franzè, Eleonora ^a   Marafini, Irene ^a   De Simone, Veronica ^a   Monteleone, Ivan ^a   Caprioli, Flavio ^b   Colantoni, Alfredo ^a   Ortenzi, Angela ^a   Crescenzi, Francesca ^a   Izzo, Roberta ^a   Sica, Giuseppe ^a   Sileri, PierPaolo ^a   Rossi, Piero ^a   Pallone, Francesco ^a   Monteleone, Giovanni ^a  

^a UNIVERSITY OF ROME TOR VERGATA   (Italy)

^b UNIVERSITY OF MILAN   (Italy)

Author keywords

cytokines; chemokines; intestinal epithelium; Inflammatory bowel disease; colitis

Indexed keywords

CHEMOKINE; INTERLEUKIN 34; MACROPHAGE INFLAMMATORY PROTEIN 3ALPHA; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE INHIBITOR; BIOLOGICAL MARKER; COLONY STIMULATING FACTOR RECEPTOR; INTERLEUKIN DERIVATIVE; INTERLEUKIN-34, HUMAN;

ARTICLE; CELL STIMULATION; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOKINE PRODUCTION; ENZYME LINKED IMMUNOSORBENT ASSAY; EPITHELIUM CELL; EX VIVO STUDY; EXPLANT; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INFLAMMATION; INFLAMMATORY BOWEL DISEASE; INTESTINE EPITHELIUM CELL; LAMINA PROPRIA; MONONUCLEAR CELL; ORGAN CULTURE; PRIORITY JOURNAL; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CELL CULTURE; COLONOSCOPY; CROHN DISEASE; CYTOLOGY; FEMALE; IMMUNOLOGY; INTESTINE MUCOSA; MALE; METABOLISM; NEEDLE BIOPSY; PATHOLOGY; PROCEDURES; SENSITIVITY AND SPECIFICITY; ULCERATIVE COLITIS; UPREGULATION;

BIOMARKERS; BIOPSY, NEEDLE; BLOTTING, WESTERN; CELLS, CULTURED; CHEMOKINE CCL20; COLITIS, ULCERATIVE; COLONOSCOPY; CROHN DISEASE; ENZYME-LINKED IMMUNOSORBENT ASSAY; EPITHELIAL CELLS; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; INTERLEUKINS; INTESTINAL MUCOSA; MALE; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTOR, MACROPHAGE COLONY-STIMULATING FACTOR; SENSITIVITY AND SPECIFICITY; UP-REGULATION;

EID: 84963734955     PISSN: 18739946     EISSN: 18764479     Source Type: Journal    
DOI: 10.1093/ecco-jcc/jjv181     Document Type: Article

References (48)

1. Abraham C, Cho JH. Inflammatory bowel disease. N Engl J Med 2009;361:2066-78
2. Bouma G, Strober W. The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 2003;3:521-33
3. Strober W, Fuss I, Mannon P. The fundamental basis of inflammatory bowel disease. J Clin Invest 2007;117:514-21
4. Strober W, Fuss IJ. Proinflammatory cytokines in the pathogenesis of inflammatory bowel diseases. Gastroenterology 2011;140:1756-67
5. Hanauer SB. Inflammatory bowel disease: epidemiology, pathogenesis, and therapeutic opportunities. Inflamm Bowel Dis 2006;12[Suppl 1]:S3-9
6. Papadakis KA. Chemokines in inflammatory bowel disease. Curr Allergy Asthma Rep 2004;4:83-9
7. Fiocchi C. Intestinal inflammation: a complex interplay of immune and nonimmune cell interactions. Am J Physiol 1997;273:G769-75
8. Shao L, Serrano D, Mayer L. The role of epithelial cells in immune regulation in the gut. Semin Immunol 2001;13:163-76
9. Baud'huin M, Renault R, Charrier C, et al. Interleukin-34 is expressed by giant cell tumours of bone and plays a key role in RANKL-induced osteoclastogenesis. J Pathol 2010;221:77-86
10. Greter M, Lelios I, Pelczar P, et al. Stroma-derived interleukin-34 controls the development and maintenance of langerhans cells and the maintenance of microglia. Immunity 2012;37:1050-60
11. Wang Y, Szretter KJ, Vermi W, et al. IL-34 is a tissue-restricted ligand of CSF1R required for the development of Langerhans cells and microglia. Nat Immunol 2012;13:753-60
12. Preisser L, Miot C, Le Guillou-Guillemette H, et al. IL-34 and macrophage colony-stimulating factor are overexpressed in hepatitis C virus fibrosis and induce profibrotic macrophages that promote collagen synthesis by hepatic stellate cells. Hepatology 2014;60:1879-90
13. Lin H, Lee E, Hestir K, et al. Discovery of a cytokine and its receptor by functional screening of the extracellular proteome. Science 2008;320:807-11
14. Byrne PV, Guilbert LJ, Stanley ER. Distribution of cells bearing receptors for a colony-stimulating factor [CSF-1] in murine tissues. J Cell Biol 1981;91:848-53
15. Ma X, Lin WY, Chen Y, et al. Structural basis for the dual recognition of helical cytokines IL-34 and CSF-1 by CSF-1R. Structure 2012;20:676-87
16. Omigbodun A, Coukos G, Ziolkiewicz P, Wang CL, Coutifaris C. Macrophage-colony stimulating factor [M-CSF] regulates the expression of fibronectin and its alpha5 integrin receptor in human trophoblasts. Endocrinology 1998;139:2190-3
17. Yang S, Zhang Y, Rodriguiz RM, Ries WL, Key LL Jr. Functions of the M-CSF receptor on osteoclasts. Bone 1996;18:355-60
18. Pampfer S, Daiter E, Barad D, Pollard JW. Expression of the colony-stimulating factor-1 receptor [c-fms proto-oncogene product] in the human uterus and placenta. Biol Reprod 1992;46:48-57
19. Inaba T, Yamada N, Gotoda T, et al. Expression of M-CSF receptor encoded by c-fms on smooth muscle cells derived from arteriosclerotic lesion. J Biol Chem 1992;267: 5693-9
20. Wang Y, Berezovska O, Fedoroff S. Expression of colony stimulating factor-1 receptor [CSF-1R] by CNS neurons in mice. J Neurosci Res 1999;57:616-32
21. Chihara T, Suzu S, Hassan R, et al. IL-34 and M-CSF share the receptor Fms but are not identical in biological activity and signal activation. Cell Death Differ 2010;17:1917-27
22. Wei S, Nandi S, Chitu V, et al. Functional overlap but differential expression of CSF-1 and IL-34 in their CSF-1 receptor-mediated regulation of myeloid cells. J Leukoc Biol 2010;88:495-505
23. Eda H, Shimada H, Beidler DR, Monahan JB. Proinflammatory cytokines, IL-1beta and TNF-alpha, induce expression of interleukin-34 mRNA via JNK-and p44/42 MAPK-NF-kappaB pathway but not p38 pathway in osteoblasts. Rheumatol Int 2011;31:1525-30
24. Eda H, Zhang J, Keith R H, Michener M, Beidler DR, Monahan JB. Macrophage-colony stimulating factor and interleukin-34 induce chemokines in human whole blood. Cytokine 2010;52:215-20
25. Franze E, Monteleone I, Cupi ML, et al. Interleukin-34 sustains inflammatory pathways in the gut. Clin Sci [Lond] 2015;129:271-80
26. Zwicker S, Martinez GL, Bosma M, et al. Interleukin 34: a new modulator of human and experimental inflammatory bowel disease. Clin Sci [Lond] 2015;129:281-90
27. Monteleone G, Kumberova A, Croft N M, McKenzie C, Steer H W, Mac-Donald T T. Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease. J Clin Invest 2001;108 601-9
28. Nandi S, Cioce M, Yeung YG, et al. Receptor-type protein-tyrosine phosphatase zeta is a functional receptor for interleukin-34. J Biol Chem 2013;288:21972-86
29. Kucharzik T, Hudson JT III, Lugering A, et al. Acute induction of human IL-8 production by intestinal epithelium triggers neutrophil infiltration without mucosal injury. Gut 2005;54:1565-72
30. Kim JA, Kim DK, Kang OH, et al. Inhibitory effect of luteolin on TNFalpha-induced IL-8 production in human colon epithelial cells. Int Immunopharmacol 2005;5:209-17
31. Fyfe M, Bergstrom M, Aspengren S, Peterson A. PAR-2 activation in intestinal epithelial cells potentiates interleukin-1beta-induced chemokine secretion via MAP kinase signaling pathways. Cytokine 2005;31:358-67
32. Banks C, Bateman A, Payne R, Johnson P, Sheron N. Chemokine expression in IBD. Mucosal chemokine expression is unselectively increased in both ulcerative colitis and Crohn's disease. J Pathol 2003;199:28-35
33. Grimm MC, Elsbury SK, Pavli P, Doe WF. Enhanced expression and production of monocyte chemoattractant protein-1 in inflammatory bowel disease mucosa. J Leukoc Biol 1996;59:804-12
34. Reinecker HC, Loh EY, Ringler DJ, Mehta A, Rombeau JL, MacDermott RP. Monocyte-chemoattractant protein 1 gene expression in intestinal epithelial cells and inflammatory bowel disease mucosa. Gastroenterology 1995;108:40-50
35. Ansari N, Abdulla J, Zayyani N, Brahmi U, Taha S, Satir AA. Comparison of RANTES expression in Crohn's disease and ulcerative colitis: an aid in the differential diagnosis? J Clin Pathol 2006;59:1066-72
36. Heiseke AF, Faul AC, Lehr HA, et al. CCL17 promotes intestinal inflammation in mice and counteracts regulatory T cell-mediated protection from colitis. Gastroenterology 2012;142:335-45
37. Kaser A, Ludwiczek O, Holzmann S, et al. Increased expression of CCL20 in human inflammatory bowel disease. J Clin Immunol 2004;24:74-85
38. Manousou P, Kolios G, Valatas V, et al. Increased expression of chemokine receptor CCR3 and its ligands in ulcerative colitis: the role of colonic epithelial cells in in vitro studies. Clin Exp Immunol 2010;162:337-47
39. Papadakis KA, Prehn J, Moreno ST, et al. CCR9-positive lymphocytes and thymus-expressed chemokine distinguish small bowel from colonic Crohn's disease. Gastroenterology 2001;121:246-54
40. Schutyser E, Struyf S, Van Damme J. The CC chemokine CCL20 and its receptor CCR6. Cytokine Growth Factor Rev 2003;14:409-26
41. Scapini P, Crepaldi L, Pinardi C, Calzetti F, Cassatella MA. CCL20/macrophage inflammatory protein-3alpha production in LPS-stimulated neutrophils is enhanced by the chemoattractant formyl-methionyl-leucylphenylalanine and IFN-gamma through independent mechanisms. Eur J Immunol 2002;32:3515-24
42. Reibman J, Hsu Y, Chen L C, Bleck B, Gordon T. Airway epithelial cells release MIP-3alpha/CCL20 in response to cytokines and ambient particulate matter. Am J Respir Cell Mol Biol 2003;28:648-54
43. Kwon JH, Keates S, Bassani L, Mayer LF, Keates AC. Colonic epithelial cells are a major site of macrophage inflammatory protein 3alpha [MIP-3alpha] production in normal colon and inflammatory bowel disease. Gut 2002;51:818-26
44. Liu H, Leo C, Chen X, et al. The mechanism of shared but distinct CSF-1R signaling by the non-homologous cytokines IL-34 and CSF-1. Biochim Biophys Acta 2012;1824:938-45
45. Baek JH, Zeng R, Weinmann-Menke J, et al. IL-34 mediates acute kidney injury and worsens subsequent chronic kidney disease. J Clin Invest 2015;125:3198-214
46. Caruso R, Fina D, Peluso I, et al. A functional role for interleukin-21 in promoting the synthesis of the T-cell chemoattractant, MIP-3alpha, by gut epithelial cells. Gastroenterology 2007;132:166-75
47. Rhee SH, Keates AC, Moyer MP, Pothoulakis C. MEK is a key modulator for TLR5-induced interleukin-8 and MIP3alpha gene expression in non-transformed human colonic epithelial cells. J Biol Chem 2004;279:25179-88
48. Kao CY, Huang F, Chen Y, et al. Up-regulation of CC chemokine ligand 20 expression in human airway epithelium by IL-17 through a JAK-independent but MEK/NF-kappaB-dependent signaling pathway. J Immunol 2005;175:6676-85