Impaired Autophagy in APOE4 Astrocytes

Journal of Alzheimer's Disease

Volumn 51, Issue 3, 2016, Pages 915-927

  Simonovitch, Shira ^a   Schmukler, Eran ^a   Bespalko, Alina ^a   Iram, Tal ^a   Frenkel, Dan ^a   Holtzman, David M ^b   Masliah, Eliezer ^c   Michaelson, Danny M ^a   Pinkas Kramarski, Ronit ^a  

^a TEL AVIV UNIVERSITY   (Israel)

^b WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Alzheimer's disease; amyloid ; apolipoprotein E4; autophagy

Indexed keywords

ACTIN; AMINO ACID; AMYLOID BETA PROTEIN; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; CHLOROQUINE; LC3 PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; PROTEIN; PROTEIN P62; RAPAMYCIN; UNCLASSIFIED DRUG; CENTRAL NERVOUS SYSTEM AGENTS;

ANIMAL CELL; ARTICLE; ASTROCYTE; ASTROCYTE CULTURE; AUTOPHAGOSOME; AUTOPHAGY; COMPARATIVE STUDY; CONTROLLED STUDY; ELECTRON MICROSCOPY; FLOW CYTOMETRY; IMMUNOBLOTTING; LYSOSOME; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; AMYLOID PLAQUE; ANIMAL; BRAIN; CELL CULTURE; DISEASE MODEL; DRUG EFFECT; GENETICS; HUMAN; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; TIME FACTOR; TRANSGENIC MOUSE;

AMYLOID BETA-PEPTIDES; ANIMALS; APOLIPOPROTEIN E3; APOLIPOPROTEIN E4; ASTROCYTES; AUTOPHAGY; BRAIN; CELLS, CULTURED; CENTRAL NERVOUS SYSTEM AGENTS; CHLOROQUINE; DISEASE MODELS, ANIMAL; HUMANS; MICE, TRANSGENIC; PLAQUE, AMYLOID; SIROLIMUS; TIME FACTORS;

EID: 84963729437     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-151101     Document Type: Article

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