Neuregulin promotes incomplete autophagy of prostate cancer cells that is independent of mTOR pathway inhibition

PLoS ONE

Volumn 7, Issue 5, 2012, Pages

  Schmukler, Eran ^a   Shai, Ben ^a   Ehrlich, Marcelo ^a   Pinkas Kramarski, Ronit ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYLADENINE; ACETYLCYSTEINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; BECLIN 1; MAMMALIAN TARGET OF RAPAMYCIN; NEU DIFFERENTIATION FACTOR; PROTEIN BCL 2; PROTEIN KINASE B; PROTEIN P62; RAPAMYCIN; REACTIVE OXYGEN METABOLITE; S6 KINASE; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; 3-METHYLADENINE; ADENINE; ANTHRA(1,9 CD)PYRAZOL 6(2H) ONE; ANTHRA(1,9-CD)PYRAZOL-6(2H)-ONE; ANTHRACENE DERIVATIVE; APOPTOSIS REGULATORY PROTEIN; BECN1 PROTEIN, HUMAN; DRUG DERIVATIVE; MEMBRANE PROTEIN; MTOR PROTEIN, HUMAN; RECOMBINANT PROTEIN; TARGET OF RAPAMYCIN KINASE;

ARTICLE; AUTOPHAGY; CANCER CELL DESTRUCTION; CARCINOMA CELL; CELL DEATH; CELL STRAIN LNCAP; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; MALE; PROSTATE CARCINOMA; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; UPREGULATION; DRUG ANTAGONISM; GENETICS; METABOLISM; NEOPLASM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; PROSTATE TUMOR; TUMOR CELL LINE;

MAMMALIA;

ACETYLCYSTEINE; ADENINE; ANTHRACENES; APOPTOSIS REGULATORY PROTEINS; AUTOPHAGY; CELL DEATH; CELL LINE, TUMOR; HUMANS; MALE; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; NEOPLASMS, HORMONE-DEPENDENT; NEUREGULINS; PROSTATIC NEOPLASMS; PROTO-ONCOGENE PROTEINS C-AKT; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; TOR SERINE-THREONINE KINASES;

EID: 84860995005     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0036828     Document Type: Article

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