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Volumn 28, Issue 1, 2012, Pages 30-35

Recent advances in helicobacter pylori pathogenesis

Author keywords

Asthma; Cancer; Cytotoxin associated gene; Helicobacter pylori; Inflammatory bowel disease; Vacuolating cytotoxin

Indexed keywords

CAGA PROTEIN;

EID: 84856884864     PISSN: 02671379     EISSN: 15317056     Source Type: Journal    
DOI: 10.1097/MOG.0b013e32834dda51     Document Type: Review
Times cited : (42)

References (27)
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    • Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia
    • this study, the authors sought to determine the role of commensal bacteria in the development of H. pylori-mediated pathologies. They used a gastrin overexpression to quantify the severity and time till the mice developed disease. Germfree mice took longer time to develop pathologies than monoassociated and specific pathogen-free (SPF) H. pylori-infected mice, whereas the SPF H. pylori mice developed a more severe phenotype than the monoassociated mice
    • Lofgren JL, Whary MT, Ge Z, et al. Lack of commensal flora in Helicobacter pylori-infected INS-GAS mice reduces gastritis and delays intraepithelial neoplasia. Gastroenterology 2011; 140:210-220. In this study, the authors sought to determine the role of commensal bacteria in the development of H. pylori-mediated pathologies. They used a gastrin overexpression to quantify the severity and time till the mice developed disease. Germfree mice took longer time to develop pathologies than monoassociated and specific pathogen-free (SPF) H. pylori-infected mice, whereas the SPF H. pylori mice developed a more severe phenotype than the monoassociated mice.
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    • Helicobacter pylori DNA decreases pro-inflammatory cytokine production by dendritic cells and attenuates dextran sodium sulphate-induced colitis
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    • Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells
    • This study investigated the mechanism underlying the inverse association of H. pylori infection and asthma. Mice infected at neonatal stages displayed reduced rates of asthma, associated with an increase in Tregs and a decrease in dendritic cell maturation
    • Arnold IC, Dehzad N, Reuter S, et al. Helicobacter pylori infection prevents allergic asthma in mouse models through the induction of regulatory T cells. J Clin Invest 2011; 121:3088-3093. This study investigated the mechanism underlying the inverse association of H. pylori infection and asthma. Mice infected at neonatal stages displayed reduced rates of asthma, associated with an increase in Tregs and a decrease in dendritic cell maturation.
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    • Influenza infection in suckling mice expands an NKT cell subset that protects against airway hyperreactivity
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* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.