메뉴 건너뛰기




Volumn 23, Issue 3, 2016, Pages 253-259

Endothelial functions of platelet/endothelial cell adhesion molecule-1 (CD31)

Author keywords

CD31; Endothelial cell junctions; Platelet endothelial cell adhesion molecule 1; Vascular permeability

Indexed keywords

CD31 ANTIGEN;

EID: 84963651443     PISSN: 10656251     EISSN: 15317048     Source Type: Journal    
DOI: 10.1097/MOH.0000000000000239     Document Type: Review
Times cited : (400)

References (78)
  • 1
    • 0021984667 scopus 로고
    • A novel leukocyte differentiation antigen: Two monoclonal antibodies TM2 and TM3 define a 120-kd molecule present on neutrophils, monocytes, platelets, and activated lymphoblasts
    • Ohto H, Maeda H, Shibata Y, et al. A novel leukocyte differentiation antigen: Two monoclonal antibodies TM2 and TM3 define a 120-kd molecule present on neutrophils, monocytes, platelets, and activated lymphoblasts. Blood 1985; 66:873-881.
    • (1985) Blood , vol.66 , pp. 873-881
    • Ohto, H.1    Maeda, H.2    Shibata, Y.3
  • 2
    • 0023029024 scopus 로고
    • Biochemistry and expression of myelomonocytic antigens
    • Goyert SM, Ferrero EM, Seremetis SV, et al. Biochemistry and expression of myelomonocytic antigens. J Immunol 1986; 137:3909-3914.
    • (1986) J Immunol , vol.137 , pp. 3909-3914
    • Goyert, S.M.1    Ferrero, E.M.2    Seremetis, S.V.3
  • 3
    • 0023945274 scopus 로고
    • Human myeloid differentiation antigens identified by monoclonal antibodies to the myelomonocytic leukemia cell line RC-2A
    • Lyons AB, Cooper SJ, Cole SR, Ashman LK. Human myeloid differentiation antigens identified by monoclonal antibodies to the myelomonocytic leukemia cell line RC-2A. Pathology 1988; 20:137-146.
    • (1988) Pathology , vol.20 , pp. 137-146
    • Lyons, A.B.1    Cooper, S.J.2    Cole, S.R.3    Ashman, L.K.4
  • 4
    • 0024442585 scopus 로고
    • Characterization of a novel myeloid antigen regulated during differentiation of monocytic cells
    • Cabanas C, Sanchez-Madrid F, Bellon T, et al. Characterization of a novel myeloid antigen regulated during differentiation of monocytic cells. Eur J Immunol 1989; 19:1373-1378.
    • (1989) Eur J Immunol , vol.19 , pp. 1373-1378
    • Cabanas, C.1    Sanchez-Madrid, F.2    Bellon, T.3
  • 5
    • 0022243945 scopus 로고
    • Vascular endothelial cells synthesize a plasma membrane protein indistinguishable from platelet membrane glycoprotein IIa
    • Van Mourik JA, Leeksma OC, Reinders JH, et al. Vascular endothelial cells synthesize a plasma membrane protein indistinguishable from platelet membrane glycoprotein IIa. J Biol Chem 1985; 260:11300-11306.
    • (1985) J Biol Chem , vol.260 , pp. 11300-11306
    • Van Mourik, J.A.1    Leeksma, O.C.2    Reinders, J.H.3
  • 6
    • 0024560212 scopus 로고
    • Human vascular endothelial cells express a membrane protein complex immunochemically indistinguishable from the platelet VLA-2 (glycoprotein Ia-IIa) complex
    • Giltay JC, Brinkman HJ, Modderman PW, et al. Human vascular endothelial cells express a membrane protein complex immunochemically indistinguishable from the platelet VLA-2 (glycoprotein Ia-IIa) complex. Blood 1989; 73:1235-1241.
    • (1989) Blood , vol.73 , pp. 1235-1241
    • Giltay, J.C.1    Brinkman, H.J.2    Modderman, P.W.3
  • 7
    • 0024346942 scopus 로고
    • A human endothelial cellrestricted externally disposed plasmalemmal protein enriched in intercellular junctions
    • Muller WA, Ratti CM, McDonnell SL, Cohn ZA. A human endothelial cellrestricted externally disposed plasmalemmal protein enriched in intercellular junctions. J Exp Med 1989; 170:399-414.
    • (1989) J Exp Med , vol.170 , pp. 399-414
    • Muller, W.A.1    Ratti, C.M.2    McDonnell, S.L.3    Cohn, Z.A.4
  • 8
    • 0025215305 scopus 로고
    • EndoCAM: A novel endothelial cell-cell adhesion molecule
    • Albelda SM, Oliver PD, Romer LH, Buck CA. EndoCAM: a novel endothelial cell-cell adhesion molecule. J Cell Biol 1990; 110:1227-1237.
    • (1990) J Cell Biol , vol.110 , pp. 1227-1237
    • Albelda, S.M.1    Oliver, P.D.2    Romer, L.H.3    Buck, C.A.4
  • 9
    • 0025274020 scopus 로고
    • PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily
    • Newman PJ, Berndt MC, Gorski J, et al. PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 1990; 247:1219-1222.
    • (1990) Science , vol.247 , pp. 1219-1222
    • Newman, P.J.1    Berndt, M.C.2    Gorski, J.3
  • 10
    • 0025221271 scopus 로고
    • Molecular characterization and functional analysis of the leukocyte surface protein CD31
    • Stockinger H, Gadd SJ, Eher R, et al. Molecular characterization and functional analysis of the leukocyte surface protein CD31. J Immunol 1990; 145:3889-3897.
    • (1990) J Immunol , vol.145 , pp. 3889-3897
    • Stockinger, H.1    Gadd, S.J.2    Eher, R.3
  • 11
    • 0025365578 scopus 로고
    • Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen
    • Simmons DL, Walker C, Power C, Pigott R. Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen. J Exp Med 1990; 171:2147-2152.
    • (1990) J Exp Med , vol.171 , pp. 2147-2152
    • Simmons, D.L.1    Walker, C.2    Power, C.3    Pigott, R.4
  • 12
    • 84882735326 scopus 로고    scopus 로고
    • Chapter 15. (Third Edition) (A.D. Michelson, editor) Elsevier/Academic Press, San Diego, CA
    • Newman PJ, Newman DK. Chapter 15. PECAM-1 In Platelets (Third Edition) (A.D. Michelson, editor) Elsevier/Academic Press, San Diego, CA, pp. 283-293, 2013.
    • (2013) PECAM-1 in Platelets , pp. 283-293
    • Newman, P.J.1    Newman, D.K.2
  • 13
    • 0141867737 scopus 로고    scopus 로고
    • PECAM-1: Old friend, new partners
    • Ilan N, Madri JA. PECAM-1: old friend, new partners. Curr Opin Cell Biol 2003; 15:515-524.
    • (2003) Curr Opin Cell Biol , vol.15 , pp. 515-524
    • Ilan, N.1    Madri, J.A.2
  • 14
    • 0038120892 scopus 로고    scopus 로고
    • Signal transduction pathways mediated by PECAM-1. New roles for an old molecule in platelet and vascular cell biology
    • Newman PJ, Newman DK. Signal transduction pathways mediated by PECAM-1. New roles for an old molecule in platelet and vascular cell biology. Arterioscler Thromb Vasc Biol 2003; 23:953-964.
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 953-964
    • Newman, P.J.1    Newman, D.K.2
  • 15
    • 36348941771 scopus 로고    scopus 로고
    • PECAM-1: A multifunctional molecule in inflammation and vascular biology
    • Woodfin A, Voisin MB, Nourshargh S. PECAM-1: a multifunctional molecule in inflammation and vascular biology. Arterioscler Thromb Vasc Biol 2007; 27:2514-2523.
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2514-2523
    • Woodfin, A.1    Voisin, M.B.2    Nourshargh, S.3
  • 16
    • 77954312649 scopus 로고    scopus 로고
    • PECAM-1: Conflicts of interest in inflammation
    • Privratsky JR, Newman DK, Newman PJ. PECAM-1: conflicts of interest in inflammation. Life Sci 2010; 87:69-82.
    • (2010) Life Sci , vol.87 , pp. 69-82
    • Privratsky, J.R.1    Newman, D.K.2    Newman, P.J.3
  • 17
    • 84960356253 scopus 로고    scopus 로고
    • Structural basis for PECAM-1 homophilic binding
    • Paddock C, Zhou D, Lertkiatmongkol P, et al. Structural basis for PECAM-1 homophilic binding. Blood 2016; 127:1052-1061.
    • (2016) Blood , vol.127 , pp. 1052-1061
    • Paddock, C.1    Zhou, D.2    Lertkiatmongkol, P.3
  • 18
    • 79958011812 scopus 로고    scopus 로고
    • Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation
    • Paddock C, Lytle BL, Peterson FC, et al. Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. Blood 2011; 117:6012-6023.
    • (2011) Blood , vol.117 , pp. 6012-6023
    • Paddock, C.1    Lytle, B.L.2    Peterson, F.C.3
  • 19
    • 0033516924 scopus 로고    scopus 로고
    • CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated
    • Newton JP, Hunter AP, Simmons DL, et al. CD31 (PECAM-1) exists as a dimer and is heavily N-glycosylated. Biochem Biophys Res Commun 1999; 261:283-291.
    • (1999) Biochem Biophys Res Commun , vol.261 , pp. 283-291
    • Newton, J.P.1    Hunter, A.P.2    Simmons, D.L.3
  • 20
    • 25144510997 scopus 로고    scopus 로고
    • A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
    • Tzima E, Irani-Tehrani M, Kiosses WB, et al. A mechanosensory complex that mediates the endothelial cell response to fluid shear stress. Nature 2005; 437:426-431.
    • (2005) Nature , vol.437 , pp. 426-431
    • Tzima, E.1    Irani-Tehrani, M.2    Kiosses, W.B.3
  • 21
    • 84869500245 scopus 로고    scopus 로고
    • Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway
    • Collins C, Guilluy C, Welch C, et al. Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway. Curr Biol 2012; 22:2087-2094.
    • (2012) Curr Biol , vol.22 , pp. 2087-2094
    • Collins, C.1    Guilluy, C.2    Welch, C.3
  • 22
    • 84878611663 scopus 로고    scopus 로고
    • Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1
    • Conway DE, Breckenridge MT, Hinde E, et al. Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol 2013; 23:1024-1030.
    • (2013) Curr Biol , vol.23 , pp. 1024-1030
    • Conway, D.E.1    Breckenridge, M.T.2    Hinde, E.3
  • 23
    • 84928662556 scopus 로고    scopus 로고
    • Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers
    • Barry AK, Wang N, Leckband DE. Local VE-cadherin mechanotransduction triggers long-ranged remodeling of endothelial monolayers. J Cell Sci 2015; 128:1341-1351.
    • (2015) J Cell Sci , vol.128 , pp. 1341-1351
    • Barry, A.K.1    Wang, N.2    Leckband, D.E.3
  • 24
    • 0030848890 scopus 로고    scopus 로고
    • Identification and characterization of functional cation coordination sites in platelet endothelial cell adhesion molecule-1
    • Jackson DE, Loo RO, Holyst MT, Newman PJ. Identification and characterization of functional cation coordination sites in platelet endothelial cell adhesion molecule-1. Biochemistry 1997; 36:9395-9404.
    • (1997) Biochemistry , vol.36 , pp. 9395-9404
    • Jackson, D.E.1    Loo, R.O.2    Holyst, M.T.3    Newman, P.J.4
  • 25
    • 0030013876 scopus 로고    scopus 로고
    • Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity
    • Sun Q-H, DeLisser HM, Zukowski MM, et al. Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J Biol Chem 1996; 271:11090-11098.
    • (1996) J Biol Chem , vol.271 , pp. 11090-11098
    • Sun, Q.-H.1    DeLisser, H.M.2    Zukowski, M.M.3
  • 26
    • 84905407842 scopus 로고    scopus 로고
    • Regulation of endothelial cell barrier function by antibody-driven affinity modulation of platelet endothelial cell adhesion molecule-1 (PECAM-1)
    • Mei H, Campbell JM, Paddock CM, et al. Regulation of endothelial cell barrier function by antibody-driven affinity modulation of platelet endothelial cell adhesion molecule-1 (PECAM-1). J Biol Chem 2014; 289:20836-20844.
    • (2014) J Biol Chem , vol.289 , pp. 20836-20844
    • Mei, H.1    Campbell, J.M.2    Paddock, C.M.3
  • 27
    • 0027938406 scopus 로고
    • Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): Alternatively spliced, functionally distinct isoforms expressed during early mammalian cardiovascular development
    • Baldwin HS, Shen HM, Yan H-C, et al. Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during early mammalian cardiovascular development. Development 1994; 120:2539-2553.
    • (1994) Development , vol.120 , pp. 2539-2553
    • Baldwin, H.S.1    Shen, H.M.2    Yan, H.-C.3
  • 28
    • 0032959158 scopus 로고    scopus 로고
    • Tissue specific expression of alternatively spliced murine PECAM-1 isoforms
    • Sheibani N, Sorenson CM, Frazier WA. Tissue specific expression of alternatively spliced murine PECAM-1 isoforms. Dev Dyn 1999; 214:44-54.
    • (1999) Dev Dyn , vol.214 , pp. 44-54
    • Sheibani, N.1    Sorenson, C.M.2    Frazier, W.A.3
  • 29
    • 0037376250 scopus 로고    scopus 로고
    • Modulation of PECAM-1 expression and alternative splicing during differentiation and activation of hematopoietic cells
    • Wang Y, Su X, Sorenson CM, Sheibani N. Modulation of PECAM-1 expression and alternative splicing during differentiation and activation of hematopoietic cells. J Cell Biochem 2003; 88:1012-1024.
    • (2003) J Cell Biochem , vol.88 , pp. 1012-1024
    • Wang, Y.1    Su, X.2    Sorenson, C.M.3    Sheibani, N.4
  • 30
    • 34447510033 scopus 로고    scopus 로고
    • PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis
    • Kondo S, Scheef EA, Sheibani N, Sorenson CM. PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis. Am J Physiol Cell Physiol 2007; 292:C2070-C2083.
    • (2007) Am J Physiol Cell Physiol , vol.292 , pp. C2070-C2083
    • Kondo, S.1    Scheef, E.A.2    Sheibani, N.3    Sorenson, C.M.4
  • 31
    • 44449095569 scopus 로고    scopus 로고
    • An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
    • Bergom C, Paddock C, Gao C, et al. An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. J Cell Sci 2008; 121:1235-1242.
    • (2008) J Cell Sci , vol.121 , pp. 1235-1242
    • Bergom, C.1    Paddock, C.2    Gao, C.3
  • 32
    • 84944318890 scopus 로고    scopus 로고
    • PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis
    • Park S, Sorenson CM, Sheibani N. PECAM-1 isoforms, eNOS and endoglin axis in regulation of angiogenesis. Clin Sci (Lond) 2015; 129:217-234.
    • (2015) Clin Sci (Lond) , vol.129 , pp. 217-234
    • Park, S.1    Sorenson, C.M.2    Sheibani, N.3
  • 33
    • 84876268989 scopus 로고    scopus 로고
    • Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: A case study involving PECAM-1
    • Tourdot BE, Brenner MK, Keough KC, et al. Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. Biochemistry 2013; 52:2597-2608.
    • (2013) Biochemistry , vol.52 , pp. 2597-2608
    • Tourdot, B.E.1    Brenner, M.K.2    Keough, K.C.3
  • 34
    • 0030936012 scopus 로고    scopus 로고
    • The protein-tyrosine phosphatase SHP-2 binds PECAM-1 and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1 and integrin-mediated cellular signaling
    • Jackson DE, Ward CM, Wang R, Newman PJ. The protein-tyrosine phosphatase SHP-2 binds PECAM-1 and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1 and integrin-mediated cellular signaling. J Biol Chem 1997; 272:6986-6993.
    • (1997) J Biol Chem , vol.272 , pp. 6986-6993
    • Jackson, D.E.1    Ward, C.M.2    Wang, R.3    Newman, P.J.4
  • 35
    • 0032894612 scopus 로고    scopus 로고
    • Switched at birth: A new family for PECAM-1
    • Newman PJ. Switched at birth: a new family for PECAM-1. J Clin Invest 1999; 103:5-9.
    • (1999) J Clin Invest , vol.103 , pp. 5-9
    • Newman, P.J.1
  • 36
    • 0031587031 scopus 로고    scopus 로고
    • Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells
    • Masuda M, Osawa M, Shigematsu H, et al. Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells. Febs Lett 1997; 408:331-336.
    • (1997) Febs Lett , vol.408 , pp. 331-336
    • Masuda, M.1    Osawa, M.2    Shigematsu, H.3
  • 37
    • 0344616889 scopus 로고    scopus 로고
    • Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding
    • Maas M, Wang R, Paddock C, et al. Reactive oxygen species induce reversible PECAM-1 tyrosine phosphorylation and SHP-2 binding. Am J Physiol Heart Circ Physiol 2003; 285:H2336-H2344.
    • (2003) Am J Physiol Heart Circ Physiol , vol.285 , pp. H2336-H2344
    • Maas, M.1    Wang, R.2    Paddock, C.3
  • 38
    • 0034050584 scopus 로고    scopus 로고
    • Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization
    • Sun J, Paddock C, Shubert J, et al. Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization. J Cell Sci 2000; 113:1459-1469.
    • (2000) J Cell Sci , vol.113 , pp. 1459-1469
    • Sun, J.1    Paddock, C.2    Shubert, J.3
  • 39
    • 0027248750 scopus 로고
    • PECAM-1 is required for transendothelial migration of leukocytes
    • Muller WA, Weigl SA, Deng X, Phillips DM. PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 1993; 178:449-460.
    • (1993) J Exp Med , vol.178 , pp. 449-460
    • Muller, W.A.1    Weigl, S.A.2    Deng, X.3    Phillips, D.M.4
  • 40
    • 0029780520 scopus 로고    scopus 로고
    • Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression
    • Sun J, Williams J, Yan H-C, et al. Platelet Endothelial Cell Adhesion Molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J Biol Chem 1996; 271:18561-18570.
    • (1996) J Biol Chem , vol.271 , pp. 18561-18570
    • Sun, J.1    Williams, J.2    Yan, H.-C.3
  • 41
    • 0030838730 scopus 로고    scopus 로고
    • Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites on PECAM-1/CD31
    • Newton JP, Buckley CD, Jones EY, Simmons DL. Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites on PECAM-1/CD31. JBC 1997; 272:20555-20563.
    • (1997) JBC , vol.272 , pp. 20555-20563
    • Newton, J.P.1    Buckley, C.D.2    Jones, E.Y.3    Simmons, D.L.4
  • 42
    • 79955525883 scopus 로고    scopus 로고
    • Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity
    • Privratsky JR, Paddock CM, Florey O, et al. Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity. J Cell Sci 2011; 124:1477-1485.
    • (2011) J Cell Sci , vol.124 , pp. 1477-1485
    • Privratsky, J.R.1    Paddock, C.M.2    Florey, O.3
  • 43
    • 84899440750 scopus 로고    scopus 로고
    • PECAM-1: Regulator of endothelial junctional integrity
    • Privratsky JR, Newman PJ. PECAM-1: regulator of endothelial junctional integrity. Cell Tissue Res 2014; 355:607-619.
    • (2014) Cell Tissue Res , vol.355 , pp. 607-619
    • Privratsky, J.R.1    Newman, P.J.2
  • 44
    • 77949902267 scopus 로고    scopus 로고
    • A2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling
    • Kitazume S, Imamaki R, Ogawa K, et al. a2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling. J Biol Chem 2010; 285:6515-6521.
    • (2010) J Biol Chem , vol.285 , pp. 6515-6521
    • Kitazume, S.1    Imamaki, R.2    Ogawa, K.3
  • 45
    • 29444437433 scopus 로고    scopus 로고
    • Siglecs: The major subfamily of I-type lectins
    • Varki A, Angata T. Siglecs: the major subfamily of I-type lectins. Glycobiology 2006; 16:1R-27R.
    • (2006) Glycobiology , vol.16 , pp. 1R-27R
    • Varki, A.1    Angata, T.2
  • 46
    • 84907525094 scopus 로고    scopus 로고
    • Interaction of platelet endothelial cell adhesion molecule (PECAM) with alpha2,6-sialylated glycan regulates its cell surface residency and antiapoptotic role
    • Kitazume S, Imamaki R, Kurimoto A, et al. Interaction of platelet endothelial cell adhesion molecule (PECAM) with alpha2,6-sialylated glycan regulates its cell surface residency and antiapoptotic role. J Biol Chem 2014; 289:27604-27613.
    • (2014) J Biol Chem , vol.289 , pp. 27604-27613
    • Kitazume, S.1    Imamaki, R.2    Kurimoto, A.3
  • 47
    • 84897433214 scopus 로고    scopus 로고
    • NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia
    • Lee C, Liu A, Miranda-Ribera A, et al. NEU1 sialidase regulates the sialylation state of CD31 and disrupts CD31-driven capillary-like tube formation in human lung microvascular endothelia. J Biol Chem 2014; 289:9121-9135.
    • (2014) J Biol Chem , vol.289 , pp. 9121-9135
    • Lee, C.1    Liu, A.2    Miranda-Ribera, A.3
  • 48
    • 85069372131 scopus 로고    scopus 로고
    • Species-specific roles for α2,3-and α2,6-linked sialic acid residues in PECAM-1-mediated homophilic interactions
    • Lertkiatmongkol P, Paddock C, Newman PJ. Species-specific roles for α2,3-and α2,6-linked sialic acid residues in PECAM-1-mediated homophilic interactions. Blood 2015; 126:3450a.
    • (2015) Blood , vol.126 , pp. 3450a
    • Lertkiatmongkol, P.1    Paddock, C.2    Newman, P.J.3
  • 49
    • 0030836503 scopus 로고    scopus 로고
    • Thrombospondin-1, a natural inhibitor of angiogenesis, regulates Platelet-Endothelial Cell Adhesion Molecule-1 expression and endothelial cell morphogenesis
    • Sheibani N, Newman PJ, Frazier WA. Thrombospondin-1, a natural inhibitor of angiogenesis, regulates Platelet-Endothelial Cell Adhesion Molecule-1 expression and endothelial cell morphogenesis. Mol Biol Cell 1997; 8:1329-1341.
    • (1997) Mol Biol Cell , vol.8 , pp. 1329-1341
    • Sheibani, N.1    Newman, P.J.2    Frazier, W.A.3
  • 51
    • 0031114043 scopus 로고    scopus 로고
    • Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin
    • Matsumura T, Wolff K, Petzelbauer P. Endothelial cell tube formation depends on cadherin 5 and CD31 interactions with filamentous actin. J Immunol 1997; 158:3408-3416.
    • (1997) J Immunol , vol.158 , pp. 3408-3416
    • Matsumura, T.1    Wolff, K.2    Petzelbauer, P.3
  • 52
    • 0032886483 scopus 로고    scopus 로고
    • Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels
    • Yang S, Graham J, Kahn JW, et al. Functional roles for PECAM-1 (CD31) and VE-cadherin (CD144) in tube assembly and lumen formation in three-dimensional collagen gels. Am J Pathol 1999; 155:887-895.
    • (1999) Am J Pathol , vol.155 , pp. 887-895
    • Yang, S.1    Graham, J.2    Kahn, J.W.3
  • 54
    • 0036080474 scopus 로고    scopus 로고
    • Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration
    • Cao G, O'Brien CD, Zhou Z, et al. Involvement of human PECAM-1 in angiogenesis and in vitro endothelial cell migration. Am J Physiol Cell Physiol 2002; 282:C1181-C1190.
    • (2002) Am J Physiol Cell Physiol , vol.282 , pp. C1181-C1190
    • Cao, G.1    O'Brien, C.D.2    Zhou, Z.3
  • 55
    • 68449087118 scopus 로고    scopus 로고
    • Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice
    • Cao G, Fehrenbach ML, Williams JT, et al. Angiogenesis in platelet endothelial cell adhesion molecule-1-null mice. Am J Pathol 2009; 175:903-915.
    • (2009) Am J Pathol , vol.175 , pp. 903-915
    • Cao, G.1    Fehrenbach, M.L.2    Williams, J.T.3
  • 56
    • 4544292278 scopus 로고    scopus 로고
    • DeLisser HM: Role of immunoreceptor tyrosine-based inhibitory motifs of PECAM-1 in PECAM-1-dependent cell migration
    • O'Brien CD, Cao G, Makrigiannakis A. DeLisser HM: Role of immunoreceptor tyrosine-based inhibitory motifs of PECAM-1 in PECAM-1-dependent cell migration. Am J Physiol Cell Physiol 2004; 287:C1103-C1113.
    • (2004) Am J Physiol Cell Physiol , vol.287 , pp. C1103-C1113
    • O'Brien, C.D.1    Cao, G.2    Makrigiannakis, A.3
  • 57
    • 77957661937 scopus 로고    scopus 로고
    • SHP-2 phosphatase activity is required for PECAM-1-dependent cell motility
    • Zhu JX, Cao G, Williams JT, Delisser HM. SHP-2 phosphatase activity is required for PECAM-1-dependent cell motility. Am J Physiol Cell Physiol 2010; 299:C854-865.
    • (2010) Am J Physiol Cell Physiol , vol.299 , pp. C854-865
    • Zhu, J.X.1    Cao, G.2    Williams, J.T.3    Delisser, H.M.4
  • 58
    • 0034735945 scopus 로고    scopus 로고
    • The protein tyrosine phosphatase Shp-2 regulates RhoA activity
    • Schoenwaelder SM, Petch LA, Williamson D, et al. The protein tyrosine phosphatase Shp-2 regulates RhoA activity. Curr Biol 2000; 10:1523-1526.
    • (2000) Curr Biol , vol.10 , pp. 1523-1526
    • Schoenwaelder, S.M.1    Petch, L.A.2    Williamson, D.3
  • 59
    • 0041709179 scopus 로고    scopus 로고
    • Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho
    • Gratzinger D, Canosa S, Engelhardt B, Madri JA. Platelet endothelial cell adhesion molecule-1 modulates endothelial cell motility through the small G-protein Rho. Faseb J 2003; 17:1458-1469.
    • (2003) Faseb J , vol.17 , pp. 1458-1469
    • Gratzinger, D.1    Canosa, S.2    Engelhardt, B.3    Madri, J.A.4
  • 60
    • 28344456074 scopus 로고    scopus 로고
    • The role of endothelial cell apoptosis in inflammatory and immune diseases
    • Winn RK, Harlan JM. The role of endothelial cell apoptosis in inflammatory and immune diseases. J Thromb Haemost 2005; 3:1815-1824.
    • (2005) J Thromb Haemost , vol.3 , pp. 1815-1824
    • Winn, R.K.1    Harlan, J.M.2
  • 61
    • 0032806934 scopus 로고    scopus 로고
    • Homophilic PECAM-1(CD31) interactions prevent endothelial cell apoptosis but do not support cell spreading or migration
    • Bird IN, Taylor V, Newton JP, et al. Homophilic PECAM-1(CD31) interactions prevent endothelial cell apoptosis but do not support cell spreading or migration. J Cell Sci 1999; 112:1989-1997.
    • (1999) J Cell Sci , vol.112 , pp. 1989-1997
    • Bird, I.N.1    Taylor, V.2    Newton, J.P.3
  • 62
    • 0033082523 scopus 로고    scopus 로고
    • Monocytes stimulate expression of the Bcl-2 family member, A1, in endothelial cells and confer protection against apoptosis
    • Noble KE, Wickremasinghe RG, DeCornet C, et al. Monocytes stimulate expression of the Bcl-2 family member, A1, in endothelial cells and confer protection against apoptosis. J Immunol 1999; 162:1376-1383.
    • (1999) J Immunol , vol.162 , pp. 1376-1383
    • Noble, K.E.1    Wickremasinghe, R.G.2    DeCornet, C.3
  • 63
    • 0035865125 scopus 로고    scopus 로고
    • Signaling through CD31 protects endothelial cells from apoptosis
    • Evans PC, Taylor ER, Kilshaw PJ. Signaling through CD31 protects endothelial cells from apoptosis. Transplantation 2001; 71:457-460.
    • (2001) Transplantation , vol.71 , pp. 457-460
    • Evans, P.C.1    Taylor, E.R.2    Kilshaw, P.J.3
  • 64
    • 0038508862 scopus 로고    scopus 로고
    • PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis
    • Gao C, Sun W, Christofidou-Solomidou M, et al. PECAM-1 functions as a specific and potent inhibitor of mitochondrial-dependent apoptosis. Blood 2003; 102:169-179.
    • (2003) Blood , vol.102 , pp. 169-179
    • Gao, C.1    Sun, W.2    Christofidou-Solomidou, M.3
  • 65
    • 33846947172 scopus 로고    scopus 로고
    • The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy
    • Bergom C, Goel R, Paddock C, et al. The cell-adhesion and signaling molecule PECAM-1 is a molecular mediator of resistance to genotoxic chemotherapy. Cancer Biol Ther 2006; 5:1699-1707.
    • (2006) Cancer Biol Ther , vol.5 , pp. 1699-1707
    • Bergom, C.1    Goel, R.2    Paddock, C.3
  • 66
    • 84945562073 scopus 로고    scopus 로고
    • CD31 signals confer immune privilege to the vascular endothelium
    • Cheung K, Ma L, Wang G, et al. CD31 signals confer immune privilege to the vascular endothelium. Proc Natl Acad Sci U S A 2015; 112:E5815-5824.
    • (2015) Proc Natl Acad Sci U S A , vol.112 , pp. E5815-5824
    • Cheung, K.1    Ma, L.2    Wang, G.3
  • 67
    • 34248377676 scopus 로고    scopus 로고
    • The endothelial glycocalyx: Composition, functions, and visualization
    • Reitsma S, Slaaf DW, Vink H, et al. The endothelial glycocalyx: composition, functions, and visualization. Pflugers Arch 2007; 454:345-359.
    • (2007) Pflugers Arch , vol.454 , pp. 345-359
    • Reitsma, S.1    Slaaf, D.W.2    Vink, H.3
  • 68
    • 0029809310 scopus 로고    scopus 로고
    • Role of GTP hydrolysis in fission of caveolae directly from plasma membranes
    • Schnitzer JE, Oh P, McIntosh DP. Role of GTP hydrolysis in fission of caveolae directly from plasma membranes. Science 1996; 274:239-242.
    • (1996) Science , vol.274 , pp. 239-242
    • Schnitzer, J.E.1    Oh, P.2    McIntosh, D.P.3
  • 69
    • 1842632667 scopus 로고    scopus 로고
    • Endothelial cell-cell junctions: Happy together
    • Dejana E. Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol 2004; 5:261-270.
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 261-270
    • Dejana, E.1
  • 70
    • 0036627211 scopus 로고    scopus 로고
    • Tight junctions of the blood-brain barrier: Development, composition and regulation
    • Wolburg H, Lippoldt A. Tight junctions of the blood-brain barrier: development, composition and regulation. Vascul Pharmacol 2002; 38:323-337.
    • (2002) Vascul Pharmacol , vol.38 , pp. 323-337
    • Wolburg, H.1    Lippoldt, A.2
  • 71
    • 0031471110 scopus 로고    scopus 로고
    • Endothelial adherens junctions: Implications in the control of vascular permeability and angiogenesis
    • Dejana E. Endothelial adherens junctions: implications in the control of vascular permeability and angiogenesis. J Clin Invest 1996; 100:S7-S10.
    • (1996) J Clin Invest , vol.100 , pp. S7-S10
    • Dejana, E.1
  • 72
    • 13044264471 scopus 로고    scopus 로고
    • Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo
    • Corada M, Mariotti M, Thurston G, et al. Vascular endothelial-cadherin is an important determinant of microvascular integrity in vivo. Proc Natl Acad Sci U S A 1999; 96:9815-9820.
    • (1999) Proc Natl Acad Sci U S A , vol.96 , pp. 9815-9820
    • Corada, M.1    Mariotti, M.2    Thurston, G.3
  • 73
    • 0028238580 scopus 로고
    • Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells
    • Ayalon O, Sabanai H, Lampugnani MG, et al. Spatial and temporal relationships between cadherins and PECAM-1 in cell-cell junctions of human endothelial cells. J Cell Biol 1994; 126:247-258.
    • (1994) J Cell Biol , vol.126 , pp. 247-258
    • Ayalon, O.1    Sabanai, H.2    Lampugnani, M.G.3
  • 74
    • 0028811546 scopus 로고
    • The platelet endothelial cell adhesion molecule-1 (PECAM1) contributes to endothelial barrier function
    • Ferrero E, Ferrero ME, Pardi R, Zocchi MR. The platelet endothelial cell adhesion molecule-1 (PECAM1) contributes to endothelial barrier function. Febs Lett 1995; 374:323-326.
    • (1995) Febs Lett , vol.374 , pp. 323-326
    • Ferrero, E.1    Ferrero, M.E.2    Pardi, R.3    Zocchi, M.R.4
  • 75
    • 0036167828 scopus 로고    scopus 로고
    • Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice
    • Graesser D, Solowiej A, Bruckner M, et al. Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1-deficient mice. J Clin Invest 2002; 109:383-392.
    • (2002) J Clin Invest , vol.109 , pp. 383-392
    • Graesser, D.1    Solowiej, A.2    Bruckner, M.3
  • 76
    • 11144278572 scopus 로고    scopus 로고
    • Endothelial cell PECAM-1 confers protection against endotoxic shock
    • Maas M, Stapleton M, Bergom C, et al. Endothelial cell PECAM-1 confers protection against endotoxic shock. Am J Physiol Heart Circ Physiol 2005; 288:H159-H164.
    • (2005) Am J Physiol Heart Circ Physiol , vol.288 , pp. H159-H164
    • Maas, M.1    Stapleton, M.2    Bergom, C.3
  • 77
    • 11144226219 scopus 로고    scopus 로고
    • Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice
    • Carrithers M, Tandon S, Canosa S, et al. Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice. Am J Pathol 2005; 166:185-196.
    • (2005) Am J Pathol , vol.166 , pp. 185-196
    • Carrithers, M.1    Tandon, S.2    Canosa, S.3
  • 78
    • 0033870599 scopus 로고    scopus 로고
    • PECAM-1 (CD31) expression modulates bleeding time in vivo
    • Mahooti S, Graesser D, Patil S, et al. PECAM-1 (CD31) expression modulates bleeding time in vivo. Am J Pathol 2000; 157:75-81.
    • (2000) Am J Pathol , vol.157 , pp. 75-81
    • Mahooti, S.1    Graesser, D.2    Patil, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.