Switched at birth: A new family for PECAM-1

Journal of Clinical Investigation

Volumn 103, Issue 1, 1999, Pages 5-9

  Newman, Peter J ^a  

^a BLOOD RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARCINOEMBRYONIC ANTIGEN; CD22 ANTIGEN; CD31 ANTIGEN; COMPLEMENTARY DNA; CYTOTOXIC T LYMPHOCYTE ANTIGEN 4; FC RECEPTOR; GLYCOPROTEIN; IMMUNOGLOBULIN; IMMUNOGLOBULIN G; INTERCELLULAR ADHESION MOLECULE 1; INTERLEUKIN 4; MAJOR HISTOCOMPATIBILITY ANTIGEN; NERVE CELL ADHESION MOLECULE; PERVANADATE; PROTEIN TYROSINE PHOSPHATASE; SCLEROPROTEIN; T LYMPHOCYTE RECEPTOR; VASCULAR CELL ADHESION MOLECULE 1;

ENDOTHELIUM CELL; NONHUMAN; PRIORITY JOURNAL; REVIEW; T LYMPHOCYTE; THROMBOCYTE;

EID: 0032894612     PISSN: 00219738     EISSN: None     Source Type: Journal    
DOI: 10.1172/JCI5928     Document Type: Review

References (53)

1. Newman, P.J. 1997. The biology of PECAM-1 j. Clin. Invest. 99:3-8.
2. Newman, P.J., et al. 1990. PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science. 247:1219-1222.
3. Vivier, E. and Daeron, M. 1997. Immunoreceptor tyrosine-based inhibition motifs. Immunol.Today. 18:286-291.
4. Cambier, J.C. 1997. Inhibitory receptors abound? [comment]. Proc. Natl. Acad. Sci. USA. 94:5993-5995.
5. Hof, P., Pluskey, S., Dhe-Paganon, S., Eck, M.J., and Shoelson, S.E. 1998. Crystal structure of the tyrosine phosphatase SHP-2. Cell. 92:441-450.
6. Cambier, J.C. 1995. Antigen and Fc receptor signaling. The awesome power of the immunoreceptor tyrosine-based activation motif (ITAM). J. Immunol. 155:3281-3285.
7. Isakov, N. 1997. ITIMs and ITAMs. The Yin and Yang of antigen and Fc receptor-linked signaling machinery. Immunol. Res. 16:85-100.
8. Ottinger, E.A., Botfield, M.C., and Shoelson, S.E. 1998 Tandem SH2 domains confer high specificity in tyrosine kinase signaling. J. Biol. Chem. 273:729-735.
9. Ohnishi, H., Kubota, M., Ohtake, A., Sato, A., and Sano, S. 1996. Activation of protein-tyrosine phosphatase SH-PTP2 by a tyrosine-based activation motif of a novel brain molecule. J. Biol. Chem. 271:25569-25574.
10. Lu, T.T., Barreuther, M., Davis, S., and Madri, J.A. 1997. Platelet endothelial cell adhesion molecule-1 is phosphorylatable by c-Src, binds Src-Src homology 2 domain, and exhibits immunoreceptor tyrosine-based activation motif-like properties. J. Biol. Chem. 272:14442-14446.
11. Beauchemin, N., et al. 1997. Association of biliary glycoprotein with protein tyrosine phosphatase SHP-1 in malignant colon epithelial cells. Oncogene. 14:783-790.
12. 60c-stc. Biochem. J. 299:613-621.
13. Jackson, D.E., Ward, C.M., Wang, R., and Newman, P.J. 1997. The protein-tyrosine phosphatase SHP-2 binds PECAM-1 and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1 and integrin-mediated cellular signaling. J. Biol. Chem. 272:6986-6993.
14. Jackson, D.E., Kupcho, K.R., and Newman, P.J. 1997. Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2. J. Biol. Chem. 272:24868-24875.
15. Masuda, M., Osawa, M., Shigematsu, H., Harada, N., and Fujiwara, K. 1997. Platelet endothelial cell adhesion molecule-1 is a major SH-PTP2 binding protein in vascular endothelial cells. FEBS Lett 408:331-336.
16. Sagawa, K., Kimura, T., Swieter, M., and Siraganian, R.P. 1997. The protein-tyrosine phosphatase SHP-2 associates with tyrosine-phosphorylated adhesion molecule PECAM-1 (CD31). J. Biol. Chem. 272:31086-31091.
17. Osawa, M., Masuda, M., Harada, N., Lopes, R.B., and Fujiwara, K. 1997. Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells. Eur. J. Cell Biol. 72:229-237.
18. Wang, R., Paddock, C., Augustine, J.A., and Newman, P.J. 1998. Oxidative stress triggers PECAM-1-mediated signaling pathways. Blood. In press. 92:548a (Abstr.)
19. Ochi, H., et al. 1998. Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 induced by lysophosphatidyl choline in cultured cells. Biochem. Biophys. Res. Commun. 243:862-868.
20. Sagawa, K., Swaim, W., Xhang, J., Unsworth, E., and Siraganian, R.P. 1997. Aggregation of the high affinity IgE receptor results in the tyrosine phosphorylation of the surface adhesion protein PECAM-1 (CD31). J. Biol. Chem. 272:13412-13418.
21. Varon, D., et al. 1998. Platelet/endothelial cell adhesion molecule-1 serves as a co-stimulatory agonist receptor that modulates integrin-dependent adhesion and aggregation of human platelets. Blood. 91:500-507.
22. Williams, A.F., and Barclay, A.N. 1988. The immunoglobulin superfamily. Domains for cell surface recognition. Ann. Rev. Immunol. 6:381-405.
23. Cunningham, B.A., et al. 1987. Neural cell adhesion molecule: structure, immunoglobulin-like domains, cell surface modulation, and alternative RNA splicing. Science. 236:799-806.
24. Kirschbaum, N.E., Gumina, R.J., and Newman, P.J. 1994. Organization of the gene for human platelet/endothelial cell adhesion molecule-1 (PECAM-1) reveals alternatively spliced isoforms and a functionally complex cytoplasmic domain. Blood. 84:4028-4037.
25. Baldwin, H.S. et al. 1994. Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during early mammalian cardiovascular development. Development. 120:2539-2553.
26. Alley, T.L., Cooper, M.D., Chen, M., and Kubagawa, H. 1998 Genomic structure of PIR-B, the inhibitory member of the paired immunoglobulin-like receptor genes in mice. Tissue Antigens. 51:224-231.
27. Schimmenti, L.A., Van, H.-C., Madri, J.A., and Albelda, S.M. 1992. Platelet endothelial cell adhesion molecule, PECAM-1, modulates cell migration. J. Cell. Physiol. 153:417-428.
28. Lu, T.T., Yan, L.G., and Madri, J.A. 1996. Integrin engagement mediates tyrosine dephosphorylation on platelet-endothelial cell adhesion molecule I. Proc. Natl. Acad. Sci. USA. 93:11808-11813.
29. Kim, C.S., Wang, T., and Madri, J.A. 1998. Platelet endothelial cell adhesion molecule-1 expression modulates endothelial cell migration in vitro. Lab. Invest. 78:583-590.
30. Tanaka, Y., et al. 1992. CD31 expressed on distinctive T cell subsets is a preferential amplifier of β1 integrin-mediated adhesion. J. Exp. Med. 176:245-253.
31. Stockinger, H., et al. 1992. Phenotype of human T cells expressing CD31, a molecule of the immunoglobulin supergene family. Immunology. 75:53-58.
32. Ashman, L.K., and Aylett, G.W. 1991. Expression of CD31-epitopes on human lymphocytes. CD31-monoclonal antibodies differentiate between naive (CD45RA+) and memory (CD45RA-) CD4-positive T-cells. Tissue Antigens. 38:208-212.
33. Torimoto, Y., Rothstein, D.M., Dang, N.H., Schlossman, S.F., and Morimoto, C. 1992. CD31, a novel cell surface marker for CD4 cells of suppressor lineage, unaltered by state of activation. J. Immunol. 148:388-396.
34. + hemopoietic progenitor cells. J. Immunol. 153:4673-4683.
35. Piali, L., et al. 1993. Murine platelet enbdothelial cell adhesion molecule (PECAM-1/CD31) modulates β2 integrins on lymphokine-activated killer cells. Eur. J. Immunol. 23:2464-2471.
36. Berman, M.E., and Muller, W.A. 1995. Ligation of platelet/endothelial cell adhesion molecule 1 (PECAM-1/CD31) on monocytes and neutrophils increases binding capacity of leukocyte CR3 (CD11b/CD18). J. Immunol. 154:299-307.
37. 2 integrin activation. J. Immunol. 156:1515-1524.
38. Neel, B.G. 1997. Role of phosphatases in lymphocyte activation. Curr. Opin. Immunol. 9:405-420.
39. Newton-Nash, D., Oza, S., and Newman, P.J. 1998. A new role for PECAM-1 (CD31): inhibition of T-cell receptor-mediated signal transduction. Blood. In press. 92:338a (Abstr.)
40. Ravetch, J.V. 1997. Fc receptors. Curr. Opin. Immunol. 9:121-125.
41. Watson, S.P., and Gibbins, J. 1998. Collagen receptor signalling in platelets: extending the role of the ITAM. Immunol. Today. 19:260-264.
42. Sun, Q.-H., et al. 1996. Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J. Biol. Chem. 271:11090-11098.
43. Sun, J., et al. 1996. Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J. Biol. Chem. 271:18561-18570.
44. Tivol, E.A., et al. 1995. Loss of CTLA-4 leads to a massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity. 3:541-547.
45. Waterhouse, P., et a. 1995. Lymphoproliferative disorders with early lethality in mice deficient in CTLA-4. Science. 270:985-988.
46. Albelda, S.M., Muller, W.A., Buck, C.A., and Newman, P.J. 1991. Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J. Cell. Biol. 114:1059-1068.
47. Wang, R., et al. 1998. PECAM-1-mediated signal transduction can be initiated by cell adhesion to extracellular matrix. Blood. In press. 92:29a Abstr.)
48. Vely, F., and Vivier, E. 1997. Conservation of structural features reveals the existence of a large family of inhibitory cell surface receptors and noninhibitory/activatory counterparts. J. Immunol. 159:2075-2077.
49. Colonna, M. 1998. Unmasking the killer's accomplice. Nature. 43:642-643.
50. Steffens, U., Vyas, V., Dupont, B., and Selvakumar, A. 1998. Nucleotide and amino acid sequence alignment for human killer cell inhibitory receptors. 1998. Tissue Antigens. 51:398-413.
51. Kharitonenkov, A., et al. 1997. A family of proteins that inhibit signalling through tyrosine kinase receptors. Nature. 386:181-186.
52. Zimmermann, U., Grunert, F., and Zimmerman, W. 1991. Carcinoembryonic antigen family: molecular biology and clinical perspectives. J. Clin. Lab. Anal. 5:344-366.
53. Kubagawa, H., Burrows, P.D., and Cooper, M.D. 1997. A novel pair of immunoglobulm-like receptors expressed by B cells and myeloid cells. Proc. Natl. Acad. Sci. USA. 94:5261-5266.