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Volumn 355, Issue 3, 2014, Pages 607-619

PECAM-1: Regulator of endothelial junctional integrity

Author keywords

Adhesion molecules; CD31; PECAM 1; Vascular permeability

Indexed keywords

CD31 ANTIGEN;

EID: 84899440750     PISSN: 0302766X     EISSN: 14320878     Source Type: Journal    
DOI: 10.1007/s00441-013-1779-3     Document Type: Review
Times cited : (265)

References (106)
  • 1
    • 0025873304 scopus 로고
    • Molecular and cellular properties of PECAM-1 (endoCAM/CD31): A novel vascular cell-cell adhesion molecule
    • 1874786
    • Albelda SM, Muller WA, Buck CA, Newman PJ (1991) Molecular and cellular properties of PECAM-1 (endoCAM/CD31): a novel vascular cell-cell adhesion molecule. J Cell Biol 114:1059-1068
    • (1991) J Cell Biol , vol.114 , pp. 1059-1068
    • Albelda, S.M.1    Muller, W.A.2    Buck, C.A.3    Newman, P.J.4
  • 2
    • 23244440759 scopus 로고    scopus 로고
    • PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress
    • 15890968
    • Bagi Z, Frangos JA, Yeh JC, White CR, Kaley G, Koller A (2005) PECAM-1 mediates NO-dependent dilation of arterioles to high temporal gradients of shear stress. Arterioscler Thromb Vasc Biol 25:1590-1595
    • (2005) Arterioscler Thromb Vasc Biol , vol.25 , pp. 1590-1595
    • Bagi, Z.1    Frangos, J.A.2    Yeh, J.C.3    White, C.R.4    Kaley, G.5    Koller, A.6
  • 3
    • 0027938406 scopus 로고
    • Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): Alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development
    • 7956830
    • Baldwin HS, Shen HM, Yan HC, Delisser HM, Chung A, Mickanin C, Trask T, Kirschbaum NE, Newman PJ, Albelda SM (1994) Platelet endothelial cell adhesion molecule-1 (PECAM-1/CD31): alternatively spliced, functionally distinct isoforms expressed during mammalian cardiovascular development. Development 120:2539-2553
    • (1994) Development , vol.120 , pp. 2539-2553
    • Baldwin, H.S.1    Shen, H.M.2    Yan, H.C.3    Delisser, H.M.4    Chung, A.5    Mickanin, C.6    Trask, T.7    Kirschbaum, N.E.8    Newman, P.J.9    Albelda, S.M.10
  • 4
    • 3042590902 scopus 로고    scopus 로고
    • Endothelial cell-to-cell junctions: Molecular organization and role in vascular homeostasis
    • 15269339
    • Bazzoni G, Dejana E (2004) Endothelial cell-to-cell junctions: molecular organization and role in vascular homeostasis. Physiol Rev 84:869-901
    • (2004) Physiol Rev , vol.84 , pp. 869-901
    • Bazzoni, G.1    Dejana, E.2
  • 5
    • 44449095569 scopus 로고    scopus 로고
    • An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling
    • 2567807 18388311
    • Bergom C, Paddock C, Gao C, Holyst T, Newman DK, Newman PJ (2008) An alternatively spliced isoform of PECAM-1 is expressed at high levels in human and murine tissues, and suggests a novel role for the C-terminus of PECAM-1 in cytoprotective signaling. J Cell Sci 121:1235-1242
    • (2008) J Cell Sci , vol.121 , pp. 1235-1242
    • Bergom, C.1    Paddock, C.2    Gao, C.3    Holyst, T.4    Newman, D.K.5    Newman, P.J.6
  • 9
    • 0037214449 scopus 로고    scopus 로고
    • Regulation of endothelium-derived vasoactive autacoid production by hemodynamic forces
    • 12498727
    • Busse R, Fleming I (2003) Regulation of endothelium-derived vasoactive autacoid production by hemodynamic forces. Trends Pharmacol Sci 24:24-29
    • (2003) Trends Pharmacol Sci , vol.24 , pp. 24-29
    • Busse, R.1    Fleming, I.2
  • 11
    • 11144226219 scopus 로고    scopus 로고
    • Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice
    • 1602311 15632011
    • Carrithers M, Tandon S, Canosa S, Michaud M, Graesser D, Madri JA (2005) Enhanced susceptibility to endotoxic shock and impaired STAT3 signaling in CD31-deficient mice. Am J Pathol 166:185-196
    • (2005) Am J Pathol , vol.166 , pp. 185-196
    • Carrithers, M.1    Tandon, S.2    Canosa, S.3    Michaud, M.4    Graesser, D.5    Madri, J.A.6
  • 12
    • 0037180768 scopus 로고    scopus 로고
    • The immunopathogenesis of sepsis
    • 12490963
    • Cohen J (2002) The immunopathogenesis of sepsis. Nature 420:885-891
    • (2002) Nature , vol.420 , pp. 885-891
    • Cohen, J.1
  • 13
    • 84869500245 scopus 로고    scopus 로고
    • Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway
    • 3681294 23084990
    • Collins C, Guilluy C, Welch C, O'Brien ET, Hahn K, Superfine R, Burridge K, Tzima E (2012) Localized tensional forces on PECAM-1 elicit a global mechanotransduction response via the integrin-RhoA pathway. Curr Biol 22:2087-2094
    • (2012) Curr Biol , vol.22 , pp. 2087-2094
    • Collins, C.1    Guilluy, C.2    Welch, C.3    O'Brien, E.T.4    Hahn, K.5    Superfine, R.6    Burridge, K.7    Tzima, E.8
  • 14
    • 84878611663 scopus 로고    scopus 로고
    • Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1
    • 23684974
    • Conway DE, Breckenridge MT, Hinde E, Gratton E, Chen CS, Schwartz MA (2013) Fluid shear stress on endothelial cells modulates mechanical tension across VE-cadherin and PECAM-1. Curr Biol 23:1024-1030
    • (2013) Curr Biol , vol.23 , pp. 1024-1030
    • Conway, D.E.1    Breckenridge, M.T.2    Hinde, E.3    Gratton, E.4    Chen, C.S.5    Schwartz, M.A.6
  • 15
    • 65249121523 scopus 로고    scopus 로고
    • A novel and critical role for tyrosine 663 in platelet endothelial cell adhesion molecule-1 trafficking and transendothelial migration
    • 3092787 19342684
    • Dasgupta B, Dufour E, Mamdouh Z, Muller WA (2009) A novel and critical role for tyrosine 663 in platelet endothelial cell adhesion molecule-1 trafficking and transendothelial migration. J Immunol 182:5041-5051
    • (2009) J Immunol , vol.182 , pp. 5041-5051
    • Dasgupta, B.1    Dufour, E.2    Mamdouh, Z.3    Muller, W.A.4
  • 17
    • 1842632667 scopus 로고    scopus 로고
    • Endothelial cell-cell junctions: Happy together
    • 15071551
    • Dejana E (2004) Endothelial cell-cell junctions: happy together. Nat Rev Mol Cell Biol 5:261-270
    • (2004) Nat Rev Mol Cell Biol , vol.5 , pp. 261-270
    • Dejana, E.1
  • 18
    • 48049094159 scopus 로고    scopus 로고
    • The role of adherens junctions and VE-cadherin in the control of vascular permeability
    • 18565824
    • Dejana E, Orsenigo F, Lampugnani MG (2008) The role of adherens junctions and VE-cadherin in the control of vascular permeability. J Cell Sci 121:2115-2122
    • (2008) J Cell Sci , vol.121 , pp. 2115-2122
    • Dejana, E.1    Orsenigo, F.2    Lampugnani, M.G.3
  • 20
    • 0027242126 scopus 로고
    • Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans
    • 8340425
    • Delisser HM, Yan HC, Newman PJ, Muller WA, Buck CA, Albelda SM (1993) Platelet/endothelial cell adhesion molecule-1 (CD31)-mediated cellular aggregation involves cell surface glycosaminoglycans. J Biol Chem 268:16037-16046
    • (1993) J Biol Chem , vol.268 , pp. 16037-16046
    • Delisser, H.M.1    Yan, H.C.2    Newman, P.J.3    Muller, W.A.4    Buck, C.A.5    Albelda, S.M.6
  • 21
    • 39049098612 scopus 로고    scopus 로고
    • PECAM-1 isoform-specific functions in PECAM-1-deficient brain microvascular endothelial cells
    • 2271141 18029285
    • Dimaio TA, Sheibani N (2008) PECAM-1 isoform-specific functions in PECAM-1-deficient brain microvascular endothelial cells. Microvasc Res 75:188-201
    • (2008) Microvasc Res , vol.75 , pp. 188-201
    • Dimaio, T.A.1    Sheibani, N.2
  • 22
    • 39249085138 scopus 로고    scopus 로고
    • Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice
    • 2275901 18206868
    • Dimaio TA, Wang S, Huang Q, Scheef EA, Sorenson CM, Sheibani N (2008) Attenuation of retinal vascular development and neovascularization in PECAM-1-deficient mice. Dev Biol 315:72-88
    • (2008) Dev Biol , vol.315 , pp. 72-88
    • Dimaio, T.A.1    Wang, S.2    Huang, Q.3    Scheef, E.A.4    Sorenson, C.M.5    Sheibani, N.6
  • 24
    • 77953809406 scopus 로고    scopus 로고
    • Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation
    • 2891748 20378855
    • Feaver RE, Gelfand BD, Wang C, Schwartz MA, Blackman BR (2010) Atheroprone hemodynamics regulate fibronectin deposition to create positive feedback that sustains endothelial inflammation. Circ Res 106:1703-1711
    • (2010) Circ Res , vol.106 , pp. 1703-1711
    • Feaver, R.E.1    Gelfand, B.D.2    Wang, C.3    Schwartz, M.A.4    Blackman, B.R.5
  • 26
    • 0028811546 scopus 로고
    • The platelet endothelial cell adhesion molecule-1 (PECAM1) contributes to endothelial barrier function
    • 7589563
    • Ferrero E, Ferrero ME, Pardi R, Zocchi MR (1995) The platelet endothelial cell adhesion molecule-1 (PECAM1) contributes to endothelial barrier function. FEBS Lett 374:323-326
    • (1995) FEBS Lett , vol.374 , pp. 323-326
    • Ferrero, E.1    Ferrero, M.E.2    Pardi, R.3    Zocchi, M.R.4
  • 27
    • 27144465277 scopus 로고    scopus 로고
    • Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells
    • 16118242
    • Fleming I, Fisslthaler B, Dixit M, Busse R (2005) Role of PECAM-1 in the shear-stress-induced activation of Akt and the endothelial nitric oxide synthase (eNOS) in endothelial cells. J Cell Sci 118:4103-4111
    • (2005) J Cell Sci , vol.118 , pp. 4103-4111
    • Fleming, I.1    Fisslthaler, B.2    Dixit, M.3    Busse, R.4
  • 28
    • 84879206867 scopus 로고    scopus 로고
    • CD44 regulates vascular endothelial barrier integrity via a PECAM-1 dependent mechanism
    • (in press)
    • Flynn KM, Michaud M, Canosa S, Madri JA (2013) CD44 regulates vascular endothelial barrier integrity via a PECAM-1 dependent mechanism. Angiogenesis (in press)
    • (2013) Angiogenesis
    • Flynn, K.M.1    Michaud, M.2    Canosa, S.3    Madri, J.A.4
  • 29
    • 84857464676 scopus 로고    scopus 로고
    • Modulation of functional responses of endothelial cells linked to angiogenesis and inflammation by shear stress: Differential effects of the mechanotransducer CD31
    • 21898411
    • Glen K, Luu NT, Ross E, Buckley CD, Rainger GE, Egginton S, Nash GB (2012) Modulation of functional responses of endothelial cells linked to angiogenesis and inflammation by shear stress: differential effects of the mechanotransducer CD31. J Cell Physiol 227:2710-2721
    • (2012) J Cell Physiol , vol.227 , pp. 2710-2721
    • Glen, K.1    Luu, N.T.2    Ross, E.3    Buckley, C.D.4    Rainger, G.E.5    Egginton, S.6    Nash, G.B.7
  • 33
    • 0029090642 scopus 로고
    • Fluid flow and osmotic stress induce tyrosine phosphorylation of an endothelial cell 128 kDa surface glycoprotein
    • 7669054
    • Harada N, Masuda M, Fujiwara K (1995) Fluid flow and osmotic stress induce tyrosine phosphorylation of an endothelial cell 128 kDa surface glycoprotein. Biochem Biophys Res Commun 214:69-74
    • (1995) Biochem Biophys Res Commun , vol.214 , pp. 69-74
    • Harada, N.1    Masuda, M.2    Fujiwara, K.3
  • 34
    • 84875368778 scopus 로고    scopus 로고
    • The role of platelet-endothelial cell adhesion molecule-1 in atheroma formation varies depending on the site-specific hemodynamic environment
    • 23372062
    • Harrison M, Smith E, Ross E, Krams R, Segers D, Buckley CD, Nash GB, Rainger GE (2013) The role of platelet-endothelial cell adhesion molecule-1 in atheroma formation varies depending on the site-specific hemodynamic environment. Arterioscler Thromb Vasc Biol 33:694-701
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 694-701
    • Harrison, M.1    Smith, E.2    Ross, E.3    Krams, R.4    Segers, D.5    Buckley, C.D.6    Nash, G.B.7    Rainger, G.E.8
  • 37
    • 0034647532 scopus 로고    scopus 로고
    • Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation
    • 10801826
    • Ilan N, Cheung L, Pinter E, Madri JA (2000) Platelet-endothelial cell adhesion molecule-1 (CD31), a scaffolding molecule for selected catenin family members whose binding is mediated by different tyrosine and serine/threonine phosphorylation. J Biol Chem 275:21435-21443
    • (2000) J Biol Chem , vol.275 , pp. 21435-21443
    • Ilan, N.1    Cheung, L.2    Pinter, E.3    Madri, J.A.4
  • 38
    • 0030855963 scopus 로고    scopus 로고
    • Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2
    • 9312087
    • Jackson DE, Kupcho KR, Newman PJ (1997a) Characterization of phosphotyrosine binding motifs in the cytoplasmic domain of platelet/endothelial cell adhesion molecule-1 (PECAM-1) that are required for the cellular association and activation of the protein-tyrosine phosphatase, SHP-2. J Biol Chem 272:24868-24875
    • (1997) J Biol Chem , vol.272 , pp. 24868-24875
    • Jackson, D.E.1    Kupcho, K.R.2    Newman, P.J.3
  • 39
    • 0030936012 scopus 로고    scopus 로고
    • The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling
    • 9054388
    • Jackson DE, Ward CM, Wang R, Newman PJ (1997b) The protein-tyrosine phosphatase SHP-2 binds platelet/endothelial cell adhesion molecule-1 (PECAM-1) and forms a distinct signaling complex during platelet aggregation. Evidence for a mechanistic link between PECAM-1- and integrin-mediated cellular signaling. J Biol Chem 272:6986-6993
    • (1997) J Biol Chem , vol.272 , pp. 6986-6993
    • Jackson, D.E.1    Ward, C.M.2    Wang, R.3    Newman, P.J.4
  • 40
    • 0028114122 scopus 로고
    • Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain
    • 7994021
    • Kirschbaum NE, Gumina RJ, Newman PJ (1994) Organization of the gene for human platelet/endothelial cell adhesion molecule-1 shows alternatively spliced isoforms and a functionally complex cytoplasmic domain. Blood 84:4028-4037
    • (1994) Blood , vol.84 , pp. 4028-4037
    • Kirschbaum, N.E.1    Gumina, R.J.2    Newman, P.J.3
  • 41
    • 77949902267 scopus 로고    scopus 로고
    • Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling
    • 2825447 20048157
    • Kitazume S, Imamaki R, Ogawa K, Komi Y, Futakawa S, Kojima S, Hashimoto Y, Marth JD, Paulson JC, Taniguchi N (2010) Alpha2,6-sialic acid on platelet endothelial cell adhesion molecule (PECAM) regulates its homophilic interactions and downstream antiapoptotic signaling. J Biol Chem 285:6515-6521
    • (2010) J Biol Chem , vol.285 , pp. 6515-6521
    • Kitazume, S.1    Imamaki, R.2    Ogawa, K.3    Komi, Y.4    Futakawa, S.5    Kojima, S.6    Hashimoto, Y.7    Marth, J.D.8    Paulson, J.C.9    Taniguchi, N.10
  • 42
    • 34447510033 scopus 로고    scopus 로고
    • PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis
    • 17563397
    • Kondo S, Scheef EA, Sheibani N, Sorenson CM (2007) PECAM-1 isoform-specific regulation of kidney endothelial cell migration and capillary morphogenesis. Am J Physiol Cell Physiol 292:C2070-C2083
    • (2007) Am J Physiol Cell Physiol , vol.292
    • Kondo, S.1    Scheef, E.A.2    Sheibani, N.3    Sorenson, C.M.4
  • 43
    • 84872954594 scopus 로고    scopus 로고
    • Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function
    • 3562705 23202369
    • Kuckleburg CJ, Newman PJ (2013) Neutrophil proteinase 3 acts on protease-activated receptor-2 to enhance vascular endothelial cell barrier function. Arterioscler Thromb Vasc Biol 33:275-284
    • (2013) Arterioscler Thromb Vasc Biol , vol.33 , pp. 275-284
    • Kuckleburg, C.J.1    Newman, P.J.2
  • 45
    • 0028900299 scopus 로고
    • The molecular organization of endothelial cell to cell junctions: Differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin)
    • 7698986
    • Lampugnani MG, Corada M, Caveda L, Breviario F, Ayalon O, Geiger B, Dejana E (1995) The molecular organization of endothelial cell to cell junctions: differential association of plakoglobin, beta-catenin, and alpha-catenin with vascular endothelial cadherin (VE-cadherin). J Cell Biol 129:203-217
    • (1995) J Cell Biol , vol.129 , pp. 203-217
    • Lampugnani, M.G.1    Corada, M.2    Caveda, L.3    Breviario, F.4    Ayalon, O.5    Geiger, B.6    Dejana, E.7
  • 46
    • 84865754557 scopus 로고    scopus 로고
    • ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration
    • 3433096 22806890
    • Liu G, Place AT, Chen Z, Brovkovych VM, Vogel SM, Muller WA, Skidgel RA, Malik AB, Minshall RD (2012) ICAM-1-activated Src and eNOS signaling increase endothelial cell surface PECAM-1 adhesivity and neutrophil transmigration. Blood 120:1942-1952
    • (2012) Blood , vol.120 , pp. 1942-1952
    • Liu, G.1    Place, A.T.2    Chen, Z.3    Brovkovych, V.M.4    Vogel, S.M.5    Muller, W.A.6    Skidgel, R.A.7    Malik, A.B.8    Minshall, R.D.9
  • 47
    • 33644840773 scopus 로고    scopus 로고
    • Peroxynitrite reduces the endothelium derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knock out mice
    • Liu Y, Bubolz AB, Shi Y, Newman PJ, Newman DK, Gutterman DD (2005) Peroxynitrite reduces the endothelium derived hyperpolarizing factor component of coronary flow-mediated dilation in PECAM-1-knock out mice. Am J Physiol Regul Integr Comp Physiol 290:R57-R65
    • (2005) Am J Physiol Regul Integr Comp Physiol , vol.290
    • Liu, Y.1    Bubolz, A.B.2    Shi, Y.3    Newman, P.J.4    Newman, D.K.5    Gutterman, D.D.6
  • 49
    • 0037434714 scopus 로고    scopus 로고
    • Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis
    • 12610627
    • Mamdouh Z, Chen X, Pierini LM, Maxfield FR, Muller WA (2003) Targeted recycling of PECAM from endothelial surface-connected compartments during diapedesis. Nature 421:748-753
    • (2003) Nature , vol.421 , pp. 748-753
    • Mamdouh, Z.1    Chen, X.2    Pierini, L.M.3    Maxfield, F.R.4    Muller, W.A.5
  • 50
    • 42249092270 scopus 로고    scopus 로고
    • Leukocyte transmigration requires kinesin-mediated microtubule-dependent membrane trafficking from the lateral border recycling compartment
    • 2292231 18378793
    • Mamdouh Z, Kreitzer GE, Muller WA (2008) Leukocyte transmigration requires kinesin-mediated microtubule-dependent membrane trafficking from the lateral border recycling compartment. J Exp Med 205:951-966
    • (2008) J Exp Med , vol.205 , pp. 951-966
    • Mamdouh, Z.1    Kreitzer, G.E.2    Muller, W.A.3
  • 51
    • 73349103808 scopus 로고    scopus 로고
    • Transcellular migration of leukocytes is mediated by the endothelial lateral border recycling compartment
    • 2806621 19887395
    • Mamdouh Z, Mikhailov A, Muller WA (2009) Transcellular migration of leukocytes is mediated by the endothelial lateral border recycling compartment. J Exp Med 206:2795-2808
    • (2009) J Exp Med , vol.206 , pp. 2795-2808
    • Mamdouh, Z.1    Mikhailov, A.2    Muller, W.A.3
  • 52
    • 33644839612 scopus 로고    scopus 로고
    • Signaling mechanisms regulating endothelial permeability
    • 16371600
    • Mehta D, Malik AB (2006) Signaling mechanisms regulating endothelial permeability. Physiol Rev 86:279-367
    • (2006) Physiol Rev , vol.86 , pp. 279-367
    • Mehta, D.1    Malik, A.B.2
  • 53
    • 79953835599 scopus 로고    scopus 로고
    • Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation
    • 3083302 21297004
    • Ming Z, Hu Y, Xiang J, Polewski P, Newman PJ, Newman DK (2011) Lyn and PECAM-1 function as interdependent inhibitors of platelet aggregation. Blood 117:3903-3906
    • (2011) Blood , vol.117 , pp. 3903-3906
    • Ming, Z.1    Hu, Y.2    Xiang, J.3    Polewski, P.4    Newman, P.J.5    Newman, D.K.6
  • 54
    • 0027248750 scopus 로고
    • PECAM-1 is required for transendothelial migration of leukocytes
    • 8340753
    • Muller WA, Weigl SA, Deng X, Phillips DM (1993) PECAM-1 is required for transendothelial migration of leukocytes. J Exp Med 178:449-460
    • (1993) J Exp Med , vol.178 , pp. 449-460
    • Muller, W.A.1    Weigl, S.A.2    Deng, X.3    Phillips, D.M.4
  • 55
    • 0031471213 scopus 로고    scopus 로고
    • The biology of PECAM-1
    • 9413397
    • Newman PJ (1997) The biology of PECAM-1. J Clin Invest 100:S25-S29
    • (1997) J Clin Invest , vol.100
    • Newman, P.J.1
  • 56
    • 0032894612 scopus 로고    scopus 로고
    • Switched at birth: A new family for PECAM-1
    • 407871 9884328
    • Newman PJ (1999) Switched at birth: a new family for PECAM-1. J Clin Invest 103:5-9
    • (1999) J Clin Invest , vol.103 , pp. 5-9
    • Newman, P.J.1
  • 57
    • 0025274020 scopus 로고
    • PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily
    • 1690453
    • Newman PJ, Berndt MC, Gorski J, White GC, Lyman S, Paddock C, Muller WA (1990) PECAM-1 (CD31) cloning and relation to adhesion molecules of the immunoglobulin gene superfamily. Science 247:1219-1222
    • (1990) Science , vol.247 , pp. 1219-1222
    • Newman, P.J.1    Berndt, M.C.2    Gorski, J.3    White, G.C.4    Lyman, S.5    Paddock, C.6    Muller, W.A.7
  • 59
    • 0038120892 scopus 로고    scopus 로고
    • Signal transduction pathways mediated by PECAM-1: New roles for an old molecule in platelet and vascular cell biology
    • 12689916
    • Newman PJ, Newman DK (2003) Signal transduction pathways mediated by PECAM-1: new roles for an old molecule in platelet and vascular cell biology. Arterioscler Thromb Vasc Biol 23:953-964
    • (2003) Arterioscler Thromb Vasc Biol , vol.23 , pp. 953-964
    • Newman, P.J.1    Newman, D.K.2
  • 60
    • 0030838730 scopus 로고    scopus 로고
    • Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites of PECAM-1/CD31
    • 9252369
    • Newton JP, Buckley CD, Jones EY, Simmons DL (1997) Residues on both faces of the first immunoglobulin fold contribute to homophilic binding sites of PECAM-1/CD31. J Biol Chem 272:20555-20563
    • (1997) J Biol Chem , vol.272 , pp. 20555-20563
    • Newton, J.P.1    Buckley, C.D.2    Jones, E.Y.3    Simmons, D.L.4
  • 62
    • 33751534762 scopus 로고    scopus 로고
    • The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues
    • 16857733
    • Nourshargh S, Krombach F, Dejana E (2006) The role of JAM-A and PECAM-1 in modulating leukocyte infiltration in inflamed and ischemic tissues. J Leukoc Biol 80:714-718
    • (2006) J Leukoc Biol , vol.80 , pp. 714-718
    • Nourshargh, S.1    Krombach, F.2    Dejana, E.3
  • 63
    • 4544292278 scopus 로고    scopus 로고
    • Role of immunoreceptor tyrosine-based inhibitory motifs of PECAM-1 in PECAM-1-dependent cell migration
    • 15201144
    • O'Brien CD, Cao G, Makrigiannakis A, Delisser HM (2004) Role of immunoreceptor tyrosine-based inhibitory motifs of PECAM-1 in PECAM-1-dependent cell migration. Am J Physiol Cell Physiol 287:C1103-C1113
    • (2004) Am J Physiol Cell Physiol , vol.287
    • O'Brien, C.D.1    Cao, G.2    Makrigiannakis, A.3    Delisser, H.M.4
  • 64
    • 0030933717 scopus 로고    scopus 로고
    • Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells
    • 9084985
    • Osawa M, Masuda M, Harada N, Lopes RB, Fujiwara K (1997) Tyrosine phosphorylation of platelet endothelial cell adhesion molecule-1 (PECAM-1, CD31) in mechanically stimulated vascular endothelial cells. Eur J Cell Biol 72:229-237
    • (1997) Eur J Cell Biol , vol.72 , pp. 229-237
    • Osawa, M.1    Masuda, M.2    Harada, N.3    Lopes, R.B.4    Fujiwara, K.5
  • 65
    • 0037135988 scopus 로고    scopus 로고
    • Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: Is it a mechanoresponsive molecule?
    • 2174013 12177047
    • Osawa M, Masuda M, Kusano K, Fujiwara K (2002) Evidence for a role of platelet endothelial cell adhesion molecule-1 in endothelial cell mechanosignal transduction: is it a mechanoresponsive molecule? J Cell Biol 158:773-785
    • (2002) J Cell Biol , vol.158 , pp. 773-785
    • Osawa, M.1    Masuda, M.2    Kusano, K.3    Fujiwara, K.4
  • 67
    • 79958011812 scopus 로고    scopus 로고
    • Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation
    • 3112045 21464369
    • Paddock C, Lytle BL, Peterson FC, Holyst T, Newman PJ, Volkman BF, Newman DK (2011) Residues within a lipid-associated segment of the PECAM-1 cytoplasmic domain are susceptible to inducible, sequential phosphorylation. Blood 117:6012-6023
    • (2011) Blood , vol.117 , pp. 6012-6023
    • Paddock, C.1    Lytle, B.L.2    Peterson, F.C.3    Holyst, T.4    Newman, P.J.5    Volkman, B.F.6    Newman, D.K.7
  • 68
    • 78649649463 scopus 로고    scopus 로고
    • PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions
    • 3006334 20810911
    • Park S, Dimaio TA, Scheef EA, Sorenson CM, Sheibani N (2010) PECAM-1 regulates proangiogenic properties of endothelial cells through modulation of cell-cell and cell-matrix interactions. Am J Physiol Cell Physiol 299:C1468-C1484
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Park, S.1    Dimaio, T.A.2    Scheef, E.A.3    Sorenson, C.M.4    Sheibani, N.5
  • 69
    • 0029081442 scopus 로고
    • CD31/PECAM-1 is a ligand for αvβ3 integrin involved in adhesion of leukocytes to endothelium
    • 7542249
    • Piali L, Hammel P, Uherek C, Bachmann F, Gisler RH, Dunon D, Imhof BA (1995) CD31/PECAM-1 is a ligand for αvβ3 integrin involved in adhesion of leukocytes to endothelium. J Cell Biol 130:451-460
    • (1995) J Cell Biol , vol.130 , pp. 451-460
    • Piali, L.1    Hammel, P.2    Uherek, C.3    Bachmann, F.4    Gisler, R.H.5    Dunon, D.6    Imhof, B.A.7
  • 70
    • 34748914299 scopus 로고    scopus 로고
    • Evolving functions of endothelial cells in inflammation
    • 17893694
    • Pober JS, Sessa WC (2007) Evolving functions of endothelial cells in inflammation. Nat Rev Immunol 7:803-815
    • (2007) Nat Rev Immunol , vol.7 , pp. 803-815
    • Pober, J.S.1    Sessa, W.C.2
  • 71
    • 79955525883 scopus 로고    scopus 로고
    • Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity
    • 3078814 21486942
    • Privratsky JR, Paddock CM, Florey O, Newman DK, Muller WA, Newman PJ (2011) Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity. J Cell Sci 124:1477-1485
    • (2011) J Cell Sci , vol.124 , pp. 1477-1485
    • Privratsky, J.R.1    Paddock, C.M.2    Florey, O.3    Newman, D.K.4    Muller, W.A.5    Newman, P.J.6
  • 72
    • 0034942713 scopus 로고    scopus 로고
    • Regulation of PECAM-1 in endothelial cells during cell growth and migration
    • RayChaudhury A, Elkins M, Kozien D, Nakada MT (2001) Regulation of PECAM-1 in endothelial cells during cell growth and migration. Exp Biol Med (Maywood) 226:686-691
    • (2001) Exp Biol Med (Maywood) , vol.226 , pp. 686-691
    • Raychaudhury, A.1    Elkins, M.2    Kozien, D.3    Nakada, M.T.4
  • 73
    • 0035876123 scopus 로고    scopus 로고
    • Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst
    • 11397002
    • Robson P, Stein P, Zhou B, Schultz RM, Baldwin HS (2001) Inner cell mass-specific expression of a cell adhesion molecule (PECAM-1/CD31) in the mouse blastocyst. Dev Biol 234:317-329
    • (2001) Dev Biol , vol.234 , pp. 317-329
    • Robson, P.1    Stein, P.2    Zhou, B.3    Schultz, R.M.4    Baldwin, H.S.5
  • 75
    • 8444224950 scopus 로고    scopus 로고
    • Platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strains
    • 15528380
    • Schenkel AR, Chew TW, Muller WA (2004) Platelet endothelial cell adhesion molecule deficiency or blockade significantly reduces leukocyte emigration in a majority of mouse strains. J Immunol 173:6403-6408
    • (2004) J Immunol , vol.173 , pp. 6403-6408
    • Schenkel, A.R.1    Chew, T.W.2    Muller, W.A.3
  • 76
    • 84873706089 scopus 로고    scopus 로고
    • Short term effects of gamma radiation on endothelial barrier function: Uncoupling of PECAM-1
    • 23220351
    • Sharma P, Templin T, Grabham P (2013) Short term effects of gamma radiation on endothelial barrier function: uncoupling of PECAM-1. Microvasc Res 86:11-20
    • (2013) Microvasc Res , vol.86 , pp. 11-20
    • Sharma, P.1    Templin, T.2    Grabham, P.3
  • 77
    • 0030836503 scopus 로고    scopus 로고
    • Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis
    • 276156 9243511
    • Sheibani N, Newman PJ, Frazier WA (1997) Thrombospondin-1, a natural inhibitor of angiogenesis, regulates platelet-endothelial cell adhesion molecule-1 expression and endothelial cell morphogenesis. Mol Biol Cell 8:1329-1341
    • (1997) Mol Biol Cell , vol.8 , pp. 1329-1341
    • Sheibani, N.1    Newman, P.J.2    Frazier, W.A.3
  • 78
    • 0032959158 scopus 로고    scopus 로고
    • Tissue specific expression of alternatively spliced murine PECAM-1 isoforms
    • 9915575
    • Sheibani N, Sorenson CM, Frazier WA (1999) Tissue specific expression of alternatively spliced murine PECAM-1 isoforms. Dev Dyn 214:44-54
    • (1999) Dev Dyn , vol.214 , pp. 44-54
    • Sheibani, N.1    Sorenson, C.M.2    Frazier, W.A.3
  • 79
    • 0033840776 scopus 로고    scopus 로고
    • Differential modulation of cadherin-mediated cell-cell adhesion by platelet endothelial cell adhesion molecule-1 isoforms through activation of extracellular regulated kinases
    • 14956 10930470
    • Sheibani N, Sorenson CM, Frazier WA (2000) Differential modulation of cadherin-mediated cell-cell adhesion by platelet endothelial cell adhesion molecule-1 isoforms through activation of extracellular regulated kinases. Mol Biol Cell 11:2793-2802
    • (2000) Mol Biol Cell , vol.11 , pp. 2793-2802
    • Sheibani, N.1    Sorenson, C.M.2    Frazier, W.A.3
  • 81
    • 0025365578 scopus 로고
    • Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen
    • 2351935
    • Simmons DL, Walker C, Power C, Pigott R (1990) Molecular cloning of CD31, a putative intercellular adhesion molecule closely related to carcinoembryonic antigen. J Exp Med 171:2147-2152
    • (1990) J Exp Med , vol.171 , pp. 2147-2152
    • Simmons, D.L.1    Walker, C.2    Power, C.3    Pigott, R.4
  • 84
    • 84874533343 scopus 로고    scopus 로고
    • Poliovirus Receptor (CD155) Regulates a Step in Transendothelial Migration between PECAM and CD99
    • 3586692 23333754
    • Sullivan DP, Seidman MA, Muller WA (2013) Poliovirus Receptor (CD155) Regulates a Step in Transendothelial Migration between PECAM and CD99. Am J Pathol 182:1031-1042
    • (2013) Am J Pathol , vol.182 , pp. 1031-1042
    • Sullivan, D.P.1    Seidman, M.A.2    Muller, W.A.3
  • 85
    • 0034050584 scopus 로고    scopus 로고
    • Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization
    • 10725228
    • Sun J, Paddock C, Shubert J, Zhang HB, Amin K, Newman PJ, Albelda SM (2000) Contributions of the extracellular and cytoplasmic domains of platelet-endothelial cell adhesion molecule-1 (PECAM-1/CD31) in regulating cell-cell localization. J Cell Sci 113(Pt 8):1459-1469
    • (2000) J Cell Sci , vol.113 , Issue.PART 8 , pp. 1459-1469
    • Sun, J.1    Paddock, C.2    Shubert, J.3    Zhang, H.B.4    Amin, K.5    Newman, P.J.6    Albelda, S.M.7
  • 86
    • 0029780520 scopus 로고    scopus 로고
    • Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression
    • 8702505
    • Sun J, Williams J, Yan HC, Amin KM, Albelda SM, Delisser HM (1996a) Platelet endothelial cell adhesion molecule-1 (PECAM-1) homophilic adhesion is mediated by immunoglobulin-like domains 1 and 2 and depends on the cytoplasmic domain and the level of surface expression. J Biol Chem 271:18561-18570
    • (1996) J Biol Chem , vol.271 , pp. 18561-18570
    • Sun, J.1    Williams, J.2    Yan, H.C.3    Amin, K.M.4    Albelda, S.M.5    Delisser, H.M.6
  • 87
    • 0030013876 scopus 로고    scopus 로고
    • Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity
    • 8626652
    • Sun QH, Delisser HM, Zukowski MM, Paddock C, Albelda SM, Newman PJ (1996b) Individually distinct Ig homology domains in PECAM-1 regulate homophilic binding and modulate receptor affinity. J Biol Chem 271:11090-11098
    • (1996) J Biol Chem , vol.271 , pp. 11090-11098
    • Sun, Q.H.1    Delisser, H.M.2    Zukowski, M.M.3    Paddock, C.4    Albelda, S.M.5    Newman, P.J.6
  • 88
    • 0032496166 scopus 로고    scopus 로고
    • Cell surface glycosaminoglycans do not serve as ligands for PECAM-1. PECAM-1 is not a heparin-binding protein
    • 9565561
    • Sun QH, Paddock C, Visentin GP, Zukowski MM, Muller WA, Newman PJ (1998) Cell surface glycosaminoglycans do not serve as ligands for PECAM-1. PECAM-1 is not a heparin-binding protein. J Biol Chem 273:11483-11490
    • (1998) J Biol Chem , vol.273 , pp. 11483-11490
    • Sun, Q.H.1    Paddock, C.2    Visentin, G.P.3    Zukowski, M.M.4    Muller, W.A.5    Newman, P.J.6
  • 90
    • 23844499088 scopus 로고    scopus 로고
    • Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2
    • 15985432
    • Tai LK, Zheng Q, Pan S, Jin ZG, Berk BC (2005) Flow activates ERK1/2 and endothelial nitric oxide synthase via a pathway involving PECAM1, SHP2, and Tie2. J Biol Chem 280:29620-29624
    • (2005) J Biol Chem , vol.280 , pp. 29620-29624
    • Tai, L.K.1    Zheng, Q.2    Pan, S.3    Jin, Z.G.4    Berk, B.C.5
  • 91
    • 0035869397 scopus 로고    scopus 로고
    • Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane
    • 11238129
    • Thompson RD, Noble KE, Larbi KY, Dewar A, Duncan GS, Mak TW, Nourshargh S (2001) Platelet-endothelial cell adhesion molecule-1 (PECAM-1)-deficient mice demonstrate a transient and cytokine-specific role for PECAM-1 in leukocyte migration through the perivascular basement membrane. Blood 97:1854-1860
    • (2001) Blood , vol.97 , pp. 1854-1860
    • Thompson, R.D.1    Noble, K.E.2    Larbi, K.Y.3    Dewar, A.4    Duncan, G.S.5    Mak, T.W.6    Nourshargh, S.7
  • 92
    • 84876268989 scopus 로고    scopus 로고
    • Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: A case study involving PECAM-1
    • 23418871
    • Tourdot BE, Brenner MK, Keough KC, Holyst T, Newman PJ, Newman DK (2013) Immunoreceptor tyrosine-based inhibitory motif (ITIM)-mediated inhibitory signaling is regulated by sequential phosphorylation mediated by distinct nonreceptor tyrosine kinases: a case study involving PECAM-1. Biochemistry 52:2597-2608
    • (2013) Biochemistry , vol.52 , pp. 2597-2608
    • Tourdot, B.E.1    Brenner, M.K.2    Keough, K.C.3    Holyst, T.4    Newman, P.J.5    Newman, D.K.6
  • 95
    • 19444370975 scopus 로고    scopus 로고
    • PECAM-1, alpha6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration
    • 15840647
    • Wang S, Dangerfield JP, Young RE, Nourshargh S (2005) PECAM-1, alpha6 integrins and neutrophil elastase cooperate in mediating neutrophil transmigration. J Cell Sci 118:2067-2076
    • (2005) J Cell Sci , vol.118 , pp. 2067-2076
    • Wang, S.1    Dangerfield, J.P.2    Young, R.E.3    Nourshargh, S.4
  • 96
    • 1442354183 scopus 로고    scopus 로고
    • Expression pattern of alternatively spliced PECAM-1 isoforms in retinal vasculature
    • 14978479
    • Wang Y, Repyak K, Sheibani N (2004) Expression pattern of alternatively spliced PECAM-1 isoforms in retinal vasculature. Mol Vis 10:103-111
    • (2004) Mol Vis , vol.10 , pp. 103-111
    • Wang, Y.1    Repyak, K.2    Sheibani, N.3
  • 97
    • 0036031889 scopus 로고    scopus 로고
    • Expression pattern of alternatively spliced PECAM-1 isoforms in hematopoietic cells and platelets
    • 12397602
    • Wang Y, Sheibani N (2002) Expression pattern of alternatively spliced PECAM-1 isoforms in hematopoietic cells and platelets. J Cell Biochem 87:424-438
    • (2002) J Cell Biochem , vol.87 , pp. 424-438
    • Wang, Y.1    Sheibani, N.2
  • 98
    • 33646136466 scopus 로고    scopus 로고
    • PECAM-1 isoform-specific activation of MAPK/ERKs and small GTPases: Implications in inflammation and angiogenesis
    • 16440301
    • Wang Y, Sheibani N (2006) PECAM-1 isoform-specific activation of MAPK/ERKs and small GTPases: implications in inflammation and angiogenesis. J Cell Biochem 98:451-468
    • (2006) J Cell Biochem , vol.98 , pp. 451-468
    • Wang, Y.1    Sheibani, N.2
  • 99
    • 0037376250 scopus 로고    scopus 로고
    • Modulation of PECAM-1 expression and alternative splicing during differentiation and activation of hematopoietic cells
    • 12616538
    • Wang Y, Su X, Sorenson CM, Sheibani N (2003a) Modulation of PECAM-1 expression and alternative splicing during differentiation and activation of hematopoietic cells. J Cell Biochem 88:1012-1024
    • (2003) J Cell Biochem , vol.88 , pp. 1012-1024
    • Wang, Y.1    Su, X.2    Sorenson, C.M.3    Sheibani, N.4
  • 100
    • 0037370638 scopus 로고    scopus 로고
    • Tissue-specific distributions of alternatively spliced human PECAM-1 isoforms
    • 12433657
    • Wang Y, Su X, Sorenson CM, Sheibani N (2003b) Tissue-specific distributions of alternatively spliced human PECAM-1 isoforms. Am J Physiol Heart Circ Physiol 284:H1008-H1017
    • (2003) Am J Physiol Heart Circ Physiol , vol.284
    • Wang, Y.1    Su, X.2    Sorenson, C.M.3    Sheibani, N.4
  • 101
    • 67650413623 scopus 로고    scopus 로고
    • Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1
    • 2699241 19211506
    • Woodfin A, Voisin MB, Imhof BA, Dejana E, Engelhardt B, Nourshargh S (2009) Endothelial cell activation leads to neutrophil transmigration as supported by the sequential roles of ICAM-2, JAM-A, and PECAM-1. Blood 113:6246-6257
    • (2009) Blood , vol.113 , pp. 6246-6257
    • Woodfin, A.1    Voisin, M.B.2    Imhof, B.A.3    Dejana, E.4    Engelhardt, B.5    Nourshargh, S.6
  • 102
    • 36348941771 scopus 로고    scopus 로고
    • PECAM-1: A multi-functional molecule in inflammation and vascular biology
    • 17872453
    • Woodfin A, Voisin MB, Nourshargh S (2007) PECAM-1: a multi-functional molecule in inflammation and vascular biology. Arterioscler Thromb Vasc Biol 27:2514-2523
    • (2007) Arterioscler Thromb Vasc Biol , vol.27 , pp. 2514-2523
    • Woodfin, A.1    Voisin, M.B.2    Nourshargh, S.3
  • 103
    • 0042320953 scopus 로고    scopus 로고
    • Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases
    • 12938162
    • Wu J, Sheibani N (2003) Modulation of VE-cadherin and PECAM-1 mediated cell-cell adhesions by mitogen-activated protein kinases. J Cell Biochem 90:121-137
    • (2003) J Cell Biochem , vol.90 , pp. 121-137
    • Wu, J.1    Sheibani, N.2
  • 104
    • 0028865256 scopus 로고
    • Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1)
    • 7559536
    • Yan HC, Baldwin HS, Sun J, Buck CA, Albelda SM, Delisser HM (1995) Alternative splicing of a specific cytoplasmic exon alters the binding characteristics of murine platelet/endothelial cell adhesion molecule-1 (PECAM-1). J Biol Chem 270:23672-23680
    • (1995) J Biol Chem , vol.270 , pp. 23672-23680
    • Yan, H.C.1    Baldwin, H.S.2    Sun, J.3    Buck, C.A.4    Albelda, S.M.5    Delisser, H.M.6
  • 106
    • 77957661937 scopus 로고    scopus 로고
    • SHP-2 phosphatase activity is required for PECAM-1-dependent cell motility
    • 2957272 20631249
    • Zhu JX, Cao G, Williams JT, Delisser HM (2010) SHP-2 phosphatase activity is required for PECAM-1-dependent cell motility. Am J Physiol Cell Physiol 299:C854-C865
    • (2010) Am J Physiol Cell Physiol , vol.299
    • Zhu, J.X.1    Cao, G.2    Williams, J.T.3    Delisser, H.M.4


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