Downregulation of the cough reflex by aclidinium and tiotropium in awake and anesthetized rabbits

Pulmonary Pharmacology and Therapeutics

Volumn 38, Issue , 2016, Pages 1-9

  Mutolo, Donatella ^a   Cinelli, Elenia ^a   Iovino, Ludovica ^a   Pantaleo, Tito ^a   Bongianni, Fulvia ^a  

^a UNIVERSITY OF FLORENCE   (Italy)

Author keywords

Aclidinium; Airway mechanoreceptors; ASICs; Long acting muscarinic receptor antagonists; The cough reflex; Tiotropium

Indexed keywords

ACID SENSING ION CHANNEL; ACLIDINIUM BROMIDE; CITRIC ACID; METHACHOLINE; TIOTROPIUM BROMIDE; VANILLOID RECEPTOR 1; ANTITUSSIVE AGENT; BRONCHODILATING AGENT; DELAYED RELEASE FORMULATION; METHACHOLINE CHLORIDE; MUSCARINIC RECEPTOR BLOCKING AGENT; TROPANE DERIVATIVE;

ANESTHESIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRONCHOCONSTRICTION; CONTROLLED STUDY; COUGHING; DOWN REGULATION; DRUG EFFICACY; HYDROLYSIS; INHALATION; MALE; MECHANICAL STIMULATION; MECHANORECEPTOR; NONHUMAN; PRIORITY JOURNAL; STIMULATION; TRACHEOBRONCHIAL TREE; WAKEFULNESS; ANIMAL; COMPARATIVE STUDY; COUGH; DELAYED RELEASE FORMULATION; DISEASE MODEL; DRUG EFFECTS; INHALATIONAL DRUG ADMINISTRATION; PROCEDURES; RABBITS AND HARES;

ADMINISTRATION, INHALATION; ANESTHESIA; ANIMALS; ANTITUSSIVE AGENTS; BRONCHOCONSTRICTION; BRONCHODILATOR AGENTS; COUGH; DELAYED-ACTION PREPARATIONS; DISEASE MODELS, ANIMAL; MALE; METHACHOLINE CHLORIDE; MUSCARINIC ANTAGONISTS; RABBITS; TIOTROPIUM BROMIDE; TROPANES; WAKEFULNESS;

EID: 84963644227     PISSN: 10945539     EISSN: 15229629     Source Type: Journal    
DOI: 10.1016/j.pupt.2016.04.001     Document Type: Article

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