Force-dependent vinculin binding to talin in live cells: A crucial step in anchoring the actin cytoskeleton to focal adhesions

American Journal of Physiology - Cell Physiology

Volumn 306, Issue 6, 2014, Pages

  Hirata, Hiroaki ^a,b   Tatsumi, Hitoshi ^c   Lim, Chwee Teck ^a,d   Sokabe, Masahiro ^a,b,c  

^a NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d NATIONAL UNIVERSITY OF SINGAPORE   (Singapore)

Author keywords

Focal adhesion; Mechanotransduction; Molecular clutch; Talin; Vinculin

Indexed keywords

ACTIN; SILICONE; TALIN; VINCULIN; 4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; AMIDE; ENZYME INHIBITOR; MYOSIN ADENOSINE TRIPHOSPHATASE; PYRIDINE DERIVATIVE; TLN1 PROTEIN, HUMAN; VCL PROTEIN, HUMAN;

ACTIN FILAMENT; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; FIBROBLAST CULTURE; FOCAL ADHESION; FORCE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MECHANOTRANSDUCTION; MOLECULAR MECHANICS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN PROTEIN INTERACTION; STRETCHING; CELL ADHESION; CELL LINE; DRUG ANTAGONISM; FIBROBLAST; HELA CELL LINE; MECHANICS; METABOLISM; MOLECULAR CLUTCH; PHYSIOLOGY;

FOCAL ADHESION; MECHANOTRANSDUCTION; MOLECULAR CLUTCH; TALIN; VINCULIN;

ACTIN CYTOSKELETON; ACTOMYOSIN; AMIDES; CELL ADHESION; CELL LINE; ENZYME INHIBITORS; FIBROBLASTS; FOCAL ADHESIONS; HELA CELLS; HUMANS; MECHANICAL PROCESSES; MECHANOTRANSDUCTION, CELLULAR; PYRIDINES; TALIN; VINCULIN;

EID: 84898491914     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00122.2013     Document Type: Article

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