-
1
-
-
33746593241
-
Ion and fluid transport properties of small airways in cystic fibrosis
-
S. Blouquit, A. Regnier, L. Dannhoffer, C. Fermanian, E. Naline, R. Boucher, and et al. Ion and fluid transport properties of small airways in cystic fibrosis Am. J. Respir. Crit. Care Med. 174 2006 299 305
-
(2006)
Am. J. Respir. Crit. Care Med.
, vol.174
, pp. 299-305
-
-
Blouquit, S.1
Regnier, A.2
Dannhoffer, L.3
Fermanian, C.4
Naline, E.5
Boucher, R.6
-
2
-
-
84937512484
-
New selective inhibitors of calcium-activated chloride channels-T16A(inh)-A01, CaCC(inh)-A01 and MONNA - What do they inhibit?
-
D.M. Boedtkjer, S. Kim, A.B. Jensen, V.M. Matchkov, and K.E. Andersson New selective inhibitors of calcium-activated chloride channels-T16A(inh)-A01, CaCC(inh)-A01 and MONNA - what do they inhibit? Br. J. Pharmacol. 172 16 2015 4158 4172
-
(2015)
Br. J. Pharmacol.
, vol.172
, Issue.16
, pp. 4158-4172
-
-
Boedtkjer, D.M.1
Kim, S.2
Jensen, A.B.3
Matchkov, V.M.4
Andersson, K.E.5
-
3
-
-
84905864551
-
Pharmacological characterization of TMEM16A currents
-
E. Bradley, S. Fedigan, T. Webb, M.A. Hollywood, K.D. Thornbury, N.G. McHale, and et al. Pharmacological characterization of TMEM16A currents Channels 8 2014 308 320
-
(2014)
Channels
, vol.8
, pp. 308-320
-
-
Bradley, E.1
Fedigan, S.2
Webb, T.3
Hollywood, M.A.4
Thornbury, K.D.5
McHale, N.G.6
-
4
-
-
54949112835
-
TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity
-
A. Caputo, E. Caci, L. Ferrera, N. Pedemonte, C. Barsanti, E. Sondo, and et al. TMEM16A, a membrane protein associated with calcium-dependent chloride channel activity Science 322 2008 590 594
-
(2008)
Science
, vol.322
, pp. 590-594
-
-
Caputo, A.1
Caci, E.2
Ferrera, L.3
Pedemonte, N.4
Barsanti, C.5
Sondo, E.6
-
5
-
-
0029153220
-
Generation and characterization of a deltaF508 cystic fibrosis mousemodel
-
W.H. Colledge, B.S. Abella, K.W. Southern, R. Ratcliff, C. Jiang, S.H. Cheng, and et al. Generation and characterization of a deltaF508 cystic fibrosis mousemodel Nat. Genet. 10 1996 445 452
-
(1996)
Nat. Genet.
, vol.10
, pp. 445-452
-
-
Colledge, W.H.1
Abella, B.S.2
Southern, K.W.3
Ratcliff, R.4
Jiang, C.5
Cheng, S.H.6
-
6
-
-
40849100330
-
Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel
-
R. De La Fuente, W. Namkung, A. Mills, and A.S. Verkman Small-molecule screen identifies inhibitors of a human intestinal calcium-activated chloride channel Mol. Pharmacol. 73 2008 758 768
-
(2008)
Mol. Pharmacol.
, vol.73
, pp. 758-768
-
-
De La Fuente, R.1
Namkung, W.2
Mills, A.3
Verkman, A.S.4
-
7
-
-
77951807670
-
Strain-dependent differences in electrogenic secretion of electrolytes across mouse colon epithelium
-
C.A. Flores, L.P. Cid, and F.V. Sepulveda Strain-dependent differences in electrogenic secretion of electrolytes across mouse colon epithelium Exp. Physiol. 95 2010 686 698
-
(2010)
Exp. Physiol.
, vol.95
, pp. 686-698
-
-
Flores, C.A.1
Cid, L.P.2
Sepulveda, F.V.3
-
8
-
-
0028784412
-
Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein Kinase II
-
P.J. French, J. Bijman, M. Edixhoven, A.B. Vaandrager, B.J. Scholte, S.M. Lohmann, and et al. Isotype-specific activation of cystic fibrosis transmembrane conductance regulator-chloride channels by cGMP-dependent protein Kinase II J. Biol. Chem. 270 44 1995 26626 26631
-
(1995)
J. Biol. Chem.
, vol.270
, Issue.44
, pp. 26626-26631
-
-
French, P.J.1
Bijman, J.2
Edixhoven, M.3
Vaandrager, A.B.4
Scholte, B.J.5
Lohmann, S.M.6
-
9
-
-
75649097760
-
The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function
-
M. Grandoch, S.S. Roscioni, and M. Schmidt The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function Br. J. Pharmacol. 159 2010 265 284
-
(2010)
Br. J. Pharmacol.
, vol.159
, pp. 265-284
-
-
Grandoch, M.1
Roscioni, S.S.2
Schmidt, M.3
-
10
-
-
0028111842
-
Anomalies in ion transport in CF mouse tracheal epithelium
-
B.R. Grubb, A.M. Paradiso, and R.C. Boucher Anomalies in ion transport in CF mouse tracheal epithelium Am. J. Physiol. 267 1994 C293 C300
-
(1994)
Am. J. Physiol.
, vol.267
, pp. C293-C300
-
-
Grubb, B.R.1
Paradiso, A.M.2
Boucher, R.C.3
-
11
-
-
0032962320
-
Pathophysiology of gene-targeted mouse models for cystic fibrosis
-
B.R. Grubb, and R.C. Boucher Pathophysiology of gene-targeted mouse models for cystic fibrosis Physiol. Rev. 79 1999 S193 S214
-
(1999)
Physiol. Rev.
, vol.79
, pp. S193-S214
-
-
Grubb, B.R.1
Boucher, R.C.2
-
13
-
-
73549089880
-
Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion
-
K.M. Hoque, O.M. Woodward, D.B. van Rossum, N.C. Zachos, L. Chen, G.P. Leun, and et al. Epac1 mediates protein kinase A-independent mechanism of forskolin-activated intestinal chloride secretion J. Gen. Physiol. 135 2010 43 58
-
(2010)
J. Gen. Physiol.
, vol.135
, pp. 43-58
-
-
Hoque, K.M.1
Woodward, O.M.2
Van Rossum, D.B.3
Zachos, N.C.4
Chen, L.5
Leun, G.P.6
-
14
-
-
84919624713
-
Hydrogen peroxide stimulation of CFTR reveals an EPAC-mediated, soluble adenylyl cyclase dependent cAMP amplification pathway common to GPCR signaling
-
P. Ivonet, M. Salathe, and G.E. Conner Hydrogen peroxide stimulation of CFTR reveals an EPAC-mediated, soluble adenylyl cyclase dependent cAMP amplification pathway common to GPCR signaling Br. J. Pharmacol. 172 1 2014 173 184
-
(2014)
Br. J. Pharmacol.
, vol.172
, Issue.1
, pp. 173-184
-
-
Ivonet, P.1
Salathe, M.2
Conner, G.E.3
-
15
-
-
77956375693
-
2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways
-
2+ signaling is required for CFTR-mediated serous cell fluid secretion in porcine and human airways J. Clin. Investig. 120 2010 3137 3148
-
(2010)
J. Clin. Investig.
, vol.120
, pp. 3137-3148
-
-
Lee, R.J.1
Foskett, J.K.2
-
17
-
-
0032433707
-
Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease
-
H. Matsui, B.R. Grubb, R. Tarran, S.H. Randell, J.T. Gatzy, C.W. Davis, and et al. Evidence for periciliary liquid layer depletion, not abnormal ion composition, in the pathogenesis of cystic fibrosis airways disease Cell 95 1998 1005 1015
-
(1998)
Cell
, vol.95
, pp. 1005-1015
-
-
Matsui, H.1
Grubb, B.R.2
Tarran, R.3
Randell, S.H.4
Gatzy, J.T.5
Davis, C.W.6
-
18
-
-
78751478642
-
TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells
-
W. Namkung, P.W. Phuan, and A.S. Verkman TMEM16A inhibitors reveal TMEM16A as a minor component of calcium-activated chloride channel conductance in airway and intestinal epithelial cells J. Biol. Chem. 286 2011 2365 2374
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 2365-2374
-
-
Namkung, W.1
Phuan, P.W.2
Verkman, A.S.3
-
20
-
-
84900406113
-
Structure and function of TMEM16 proteins (anoctamins)
-
N. Pedemonte, and L.J. Galietta Structure and function of TMEM16 proteins (anoctamins) Physiol. Rev. 94 2014 419 459
-
(2014)
Physiol. Rev.
, vol.94
, pp. 419-459
-
-
Pedemonte, N.1
Galietta, L.J.2
-
21
-
-
49049118639
-
The transmembrane protein TMEM16A is required for normal development of the murine trachea
-
J.R. Rock, C.R. Futtner, and B.D. Harfe The transmembrane protein TMEM16A is required for normal development of the murine trachea Dev. Biol. 321 2008 141 149
-
(2008)
Dev. Biol.
, vol.321
, pp. 141-149
-
-
Rock, J.R.1
Futtner, C.R.2
Harfe, B.D.3
-
23
-
-
13344282728
-
Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor
-
R. Rozmahel, M. Wilschanski, A. Matin, S. Plyte, M. Oliver, W. Auerbach, and et al. Modulation of disease severity in cystic fibrosis transmembrane conductance regulator deficient mice by a secondary genetic factor Nat. Genet 12 1996 280 287
-
(1996)
Nat. Genet
, vol.12
, pp. 280-287
-
-
Rozmahel, R.1
Wilschanski, M.2
Matin, A.3
Plyte, S.4
Oliver, M.5
Auerbach, W.6
-
25
-
-
51549120559
-
Expression cloning of TMEM16A as a calcium-activated chloride channel subunit
-
B.C. Schroeder, T. Cheng, Y.N. Jan, and L.Y. Jan Expression cloning of TMEM16A as a calcium-activated chloride channel subunit Cell 134 2008 1019 1029
-
(2008)
Cell
, vol.134
, pp. 1019-1029
-
-
Schroeder, B.C.1
Cheng, T.2
Jan, Y.N.3
Jan, L.Y.4
-
26
-
-
84870370950
-
Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia
-
P. Scudieri, E. Caci, S. Bruno, L. Ferrera, M. Schiavon, E. Sondo, and et al. Association of TMEM16A chloride channel overexpression with airway goblet cell metaplasia J. Physiol. 590 2012 6141 6155
-
(2012)
J. Physiol.
, vol.590
, pp. 6141-6155
-
-
Scudieri, P.1
Caci, E.2
Bruno, S.3
Ferrera, L.4
Schiavon, M.5
Sondo, E.6
-
27
-
-
80053198436
-
Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling
-
E. Sondo, V. Tomati, E. Caci, A.I. Esposito, U. Pfeffer, N. Pedemonte, and et al. Rescue of the mutant CFTR chloride channel by pharmacological correctors and low temperature analyzed by gene expression profiling Am. J. Physiol. Cell Physiol. 301 2011 C872 C885
-
(2011)
Am. J. Physiol. Cell Physiol.
, vol.301
, pp. C872-C885
-
-
Sondo, E.1
Tomati, V.2
Caci, E.3
Esposito, A.I.4
Pfeffer, U.5
Pedemonte, N.6
-
28
-
-
84901601728
-
The TMEM16A chloride channel as an alternative therapeutic target in cystic fibrosis
-
E. Sondo, E. Caci, and L.J. Galietta The TMEM16A chloride channel as an alternative therapeutic target in cystic fibrosis Int. J. Biochem Cell Biol. 52 2014 73 76
-
(2014)
Int. J. Biochem Cell Biol.
, vol.52
, pp. 73-76
-
-
Sondo, E.1
Caci, E.2
Galietta, L.J.3
-
30
-
-
27444444705
-
Normal and cystic fibrosis airway surface liquid homeostasis
-
R. Tarran, M.E. Loewen, A.M. Paradiso, C.M. Ribeiro, E.R. Lazaroswy, L. Zhang, and et al. Normal and cystic fibrosis airway surface liquid homeostasis J. Biol. Chem. 280 2005 35751 35759
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 35751-35759
-
-
Tarran, R.1
Loewen, M.E.2
Paradiso, A.M.3
Ribeiro, C.M.4
Lazaroswy, E.R.5
Zhang, L.6
-
31
-
-
0029086350
-
A mouse model for the cystic fibrosis delta F508 mutation
-
J.H. Van Doorninck, P.J. French, E. Verbeek, R.H. Peters, H. Morreau, J. Bijman, and et al. A mouse model for the cystic fibrosis delta F508 mutation EMBO J. 14 1995 4403 4411
-
(1995)
EMBO J.
, vol.14
, pp. 4403-4411
-
-
Van Doorninck, J.H.1
French, P.J.2
Verbeek, E.3
Peters, R.H.4
Morreau, H.5
Bijman, J.6
-
32
-
-
55249091085
-
TMEM16A confers receptor-activated calcium-dependent chloride conductance
-
Y.D. Yang, H. Cho, J.Y. Koo, M.H. Tak, Y. Cho, W.S. Shim, and et al. TMEM16A confers receptor-activated calcium-dependent chloride conductance Nature 455 2008 1210 1215
-
(2008)
Nature
, vol.455
, pp. 1210-1215
-
-
Yang, Y.D.1
Cho, H.2
Koo, J.Y.3
Tak, M.H.4
Cho, Y.5
Shim, W.S.6
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