메뉴 건너뛰기




Volumn 172, Issue 1, 2015, Pages 173-184

Hydrogen peroxide stimulation of CFTR reveals an Epac-mediated, soluble AC-dependent cAMP amplification pathway common to GPCR signalling

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; ANION; ANTIPORTER; BETA ADRENERGIC RECEPTOR; CALCIUM; CHLORINE; CYCLIC AMP; CYSTIC FIBROSIS TRANSMEMBRANE CONDUCTANCE REGULATOR; FORSKOLIN; FURA 2; G PROTEIN COUPLED RECEPTOR; HYDROGEN PEROXIDE; POTASSIUM CHANNEL; PROSTAGLANDIN E RECEPTOR 4;

EID: 84919624713     PISSN: 00071188     EISSN: 14765381     Source Type: Journal    
DOI: 10.1111/bph.12934     Document Type: Article
Times cited : (29)

References (62)
  • 6
    • 84871563190 scopus 로고    scopus 로고
    • A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion
    • Almahariq M, Tsalkova T, Mei FC, Chen H, Zhou J, Sastry SK, et al. (2013). A novel EPAC-specific inhibitor suppresses pancreatic cancer cell migration and invasion. Mol Pharmacol 83: 122-128.
    • (2013) Mol Pharmacol , vol.83 , pp. 122-128
    • Almahariq, M.1    Tsalkova, T.2    Mei, F.C.3    Chen, H.4    Zhou, J.5    Sastry, S.K.6
  • 7
    • 84886802427 scopus 로고    scopus 로고
    • The secret life of CFTR as a calcium-activated chloride channel
    • Billet A, Hanrahan JW, (2013). The secret life of CFTR as a calcium-activated chloride channel. J Physiol 591 (Pt 21): 5273-5278.
    • (2013) J Physiol , vol.591 , pp. 5273-5278
    • Billet, A.1    Hanrahan, J.W.2
  • 8
    • 84881253530 scopus 로고    scopus 로고
    • Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR)
    • Billet A, Luo Y, Balghi H, Hanrahan JW, (2013). Role of tyrosine phosphorylation in the muscarinic activation of the cystic fibrosis transmembrane conductance regulator (CFTR). J Biol Chem 288: 21815-21823.
    • (2013) J Biol Chem , vol.288 , pp. 21815-21823
    • Billet, A.1    Luo, Y.2    Balghi, H.3    Hanrahan, J.W.4
  • 10
    • 34047166052 scopus 로고    scopus 로고
    • Airway surface dehydration in cystic fibrosis: Pathogenesis and therapy
    • Boucher RC, (2007). Airway surface dehydration in cystic fibrosis: pathogenesis and therapy. Annu Rev Med 58: 157-170.
    • (2007) Annu Rev Med , vol.58 , pp. 157-170
    • Boucher, R.C.1
  • 11
    • 0017624192 scopus 로고
    • Mn2+-sensitive, soluble adenylate cyclase in rat testis. Differentiation from other testicular nucleotide cyclases
    • Braun T, Frank H, Dods R, Sepsenwol S, (1977). Mn2+-sensitive, soluble adenylate cyclase in rat testis. Differentiation from other testicular nucleotide cyclases. Biochim Biophys Acta 481: 227-235.
    • (1977) Biochim Biophys Acta , vol.481 , pp. 227-235
    • Braun, T.1    Frank, H.2    Dods, R.3    Sepsenwol, S.4
  • 13
    • 0037383783 scopus 로고    scopus 로고
    • Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA
    • Chappe V, Hinkson DA, Zhu T, Chang XB, Riordan JR, Hanrahan JW, (2003). Phosphorylation of protein kinase C sites in NBD1 and the R domain control CFTR channel activation by PKA. J Physiol 548 (Pt 1): 39-52.
    • (2003) J Physiol , vol.548 , pp. 39-52
    • Chappe, V.1    Hinkson, D.A.2    Zhu, T.3    Chang, X.B.4    Riordan, J.R.5    Hanrahan, J.W.6
  • 14
    • 84918811577 scopus 로고    scopus 로고
    • A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in sAC knockout mice
    • Chen X, Baumlin N, Buck J, Levin LR, Fregien N, Salathe M, (2014). A soluble adenylyl cyclase form targets to axonemes and rescues beat regulation in sAC knockout mice. Am J Respir Cell Mol Biol. doi: 10.1165/rcmb.2013-0542OC.
    • (2014) Am J Respir Cell Mol Biol
    • Chen, X.1    Baumlin, N.2    Buck, J.3    Levin, L.R.4    Fregien, N.5    Salathe, M.6
  • 15
    • 0037115169 scopus 로고    scopus 로고
    • Lactoperoxidase and hydrogen peroxide metabolism in the airway
    • Conner GE, Salathe M, Forteza R, (2002). Lactoperoxidase and hydrogen peroxide metabolism in the airway. Am J Respir Crit Care Med 166 (12 Pt 2): S57-S61.
    • (2002) Am J Respir Crit Care Med , vol.166 , Issue.12 , pp. S57-S61
    • Conner, G.E.1    Salathe, M.2    Forteza, R.3
  • 16
    • 84919701844 scopus 로고    scopus 로고
    • Hydrogen peroxide activates prostanoid receptors to increase anion secretion by human bronchial epithelial cells
    • Conner GE, Ivonnet P, Salathe M, (2010). Hydrogen peroxide activates prostanoid receptors to increase anion secretion by human bronchial epithelial cells. Am J Respir Crit Care Med 181: A4227.
    • (2010) Am J Respir Crit Care Med , vol.181 , pp. A4227
    • Conner, G.E.1    Ivonnet, P.2    Salathe, M.3
  • 17
    • 84886564112 scopus 로고    scopus 로고
    • H2O2 stimulates cystic fibrosis transmembrane conductance regulator through an autocrine prostaglandin pathway, using multidrug-resistant protein-4
    • Conner GE, Ivonnet P, Gelin M, Whitney P, Salathe M, (2013). H2O2 stimulates cystic fibrosis transmembrane conductance regulator through an autocrine prostaglandin pathway, using multidrug-resistant protein-4. Am J Respir Cell Mol Biol 49: 672-679.
    • (2013) Am J Respir Cell Mol Biol , vol.49 , pp. 672-679
    • Conner, G.E.1    Ivonnet, P.2    Gelin, M.3    Whitney, P.4    Salathe, M.5
  • 18
    • 0036462593 scopus 로고    scopus 로고
    • Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3
    • Cowley EA, Linsdell P, (2002a). Characterization of basolateral K+ channels underlying anion secretion in the human airway cell line Calu-3. J Physiol 538: 747-757.
    • (2002) J Physiol , vol.538 , pp. 747-757
    • Cowley, E.A.1    Linsdell, P.2
  • 19
    • 0037101920 scopus 로고    scopus 로고
    • Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3: Implications for cystic fibrosis lung disease
    • Cowley EA, Linsdell P, (2002b). Oxidant stress stimulates anion secretion from the human airway epithelial cell line Calu-3: implications for cystic fibrosis lung disease. J Physiol 543: 201-209.
    • (2002) J Physiol , vol.543 , pp. 201-209
    • Cowley, E.A.1    Linsdell, P.2
  • 20
    • 84875409974 scopus 로고    scopus 로고
    • H2O2 regulates lung epithelial sodium channel (ENaC) via ubiquitin-like protein Nedd8
    • Downs CA, Kumar A, Kreiner LH, Johnson NM, Helms MN, (2013). H2O2 regulates lung epithelial sodium channel (ENaC) via ubiquitin-like protein Nedd8. J Biol Chem 288: 8136-8145.
    • (2013) J Biol Chem , vol.288 , pp. 8136-8145
    • Downs, C.A.1    Kumar, A.2    Kreiner, L.H.3    Johnson, N.M.4    Helms, M.N.5
  • 22
    • 46749102562 scopus 로고    scopus 로고
    • Beta-oestradiol rescues DeltaF508CFTR functional expression in human cystic fibrosis airway CFBE41o- cells through the up-regulation of NHERF1
    • Fanelli T, Cardone RA, Favia M, Guerra L, Zaccolo M, Monterisi S, et al. (2008). Beta-oestradiol rescues DeltaF508CFTR functional expression in human cystic fibrosis airway CFBE41o- cells through the up-regulation of NHERF1. Biol Cell 100: 399-412.
    • (2008) Biol Cell , vol.100 , pp. 399-412
    • Fanelli, T.1    Cardone, R.A.2    Favia, M.3    Guerra, L.4    Zaccolo, M.5    Monterisi, S.6
  • 25
    • 0042203535 scopus 로고    scopus 로고
    • Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense
    • Geiszt M, Witta J, Baffi J, Lekstrom K, Leto TL, (2003). Dual oxidases represent novel hydrogen peroxide sources supporting mucosal surface host defense. FASEB J 17: 1502-1504.
    • (2003) FASEB J , vol.17 , pp. 1502-1504
    • Geiszt, M.1    Witta, J.2    Baffi, J.3    Lekstrom, K.4    Leto, T.L.5
  • 26
    • 77954352048 scopus 로고    scopus 로고
    • Beta-Adrenergic activation of electrogenic K+ and Cl- secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways
    • Halm ST, Zhang J, Halm DR, (2010). beta-Adrenergic activation of electrogenic K+ and Cl- secretion in guinea pig distal colonic epithelium proceeds via separate cAMP signaling pathways. Am J Physiol Gastrointest Liver Physiol 299: G81-G95.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.299 , pp. G81-G95
    • Halm, S.T.1    Zhang, J.2    Halm, D.R.3
  • 27
    • 24044451233 scopus 로고    scopus 로고
    • Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium
    • Harper RW, Xu C, Eiserich JP, Chen Y, Kao CY, Thai P, et al. (2005). Differential regulation of dual NADPH oxidases/peroxidases, Duox1 and Duox2, by Th1 and Th2 cytokines in respiratory tract epithelium. FEBS Lett 579: 4911-4917.
    • (2005) FEBS Lett , vol.579 , pp. 4911-4917
    • Harper, R.W.1    Xu, C.2    Eiserich, J.P.3    Chen, Y.4    Kao, C.Y.5    Thai, P.6
  • 28
    • 85047678863 scopus 로고
    • Effects of hydrogen peroxide on action potentials and intracellular Ca2+ concentration of guinea pig heart
    • Hayashi H, Miyata H, Watanabe H, Kobayashi A, Yamazaki N, (1989). Effects of hydrogen peroxide on action potentials and intracellular Ca2+ concentration of guinea pig heart. Cardiovasc Res 23: 767-773.
    • (1989) Cardiovasc Res , vol.23 , pp. 767-773
    • Hayashi, H.1    Miyata, H.2    Watanabe, H.3    Kobayashi, A.4    Yamazaki, N.5
  • 29
    • 22944450343 scopus 로고    scopus 로고
    • The 'soluble' adenylyl cyclase in sperm mediates multiple signaling events required for fertilization
    • Hess KC, Jones BH, Marquez B, Chen Y, Ord TS, Kamenetsky M, et al. (2005). The 'soluble' adenylyl cyclase in sperm mediates multiple signaling events required for fertilization. Dev Cell 9: 249-259.
    • (2005) Dev Cell , vol.9 , pp. 249-259
    • Hess, K.C.1    Jones, B.H.2    Marquez, B.3    Chen, Y.4    Ord, T.S.5    Kamenetsky, M.6
  • 30
    • 24344475560 scopus 로고    scopus 로고
    • Phospholipase C in living cells: Activation, inhibition, Ca2+ requirement, and regulation of M current
    • Horowitz LF, Hirdes W, Suh BC, Hilgemann DW, Mackie K, Hille B, (2005). Phospholipase C in living cells: activation, inhibition, Ca2+ requirement, and regulation of M current. J Gen Physiol 126: 243-262.
    • (2005) J Gen Physiol , vol.126 , pp. 243-262
    • Horowitz, L.F.1    Hirdes, W.2    Suh, B.C.3    Hilgemann, D.W.4    Mackie, K.5    Hille, B.6
  • 31
    • 84859972423 scopus 로고    scopus 로고
    • The prostaglandin E(2) type 4 receptor participates in the response to acute oxidant stress in airway epithelial cells
    • Jones CL, Li T, Cowley EA, (2012). The prostaglandin E(2) type 4 receptor participates in the response to acute oxidant stress in airway epithelial cells. J Pharmacol Exp Ther 341: 552-563.
    • (2012) J Pharmacol Exp Ther , vol.341 , pp. 552-563
    • Jones, C.L.1    Li, T.2    Cowley, E.A.3
  • 32
    • 38549117714 scopus 로고    scopus 로고
    • 8-iso-PGE2 stimulates anion efflux from airway epithelial cells via the EP4 prostanoid receptor
    • Joy AP, Cowley EA, (2008). 8-iso-PGE2 stimulates anion efflux from airway epithelial cells via the EP4 prostanoid receptor. Am J Respir Cell Mol Biol 38: 143-152.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , pp. 143-152
    • Joy, A.P.1    Cowley, E.A.2
  • 34
    • 0037082217 scopus 로고    scopus 로고
    • Prolonged increase in ciliary beat frequency after short-term purinergic stimulation in human airway epithelial cells
    • Lieb T, Frei CW, Frohock JI, Bookman RJ, Salathe M, (2002). Prolonged increase in ciliary beat frequency after short-term purinergic stimulation in human airway epithelial cells. J Physiol 538 (Pt 2): 633-646.
    • (2002) J Physiol , vol.538 , pp. 633-646
    • Lieb, T.1    Frei, C.W.2    Frohock, J.I.3    Bookman, R.J.4    Salathe, M.5
  • 35
    • 0037844844 scopus 로고    scopus 로고
    • Kinetic properties of 'soluble' adenylyl cyclase. Synergism between calcium and bicarbonate
    • Litvin TN, Kamenetsky M, Zarifyan A, Buck J, Levin LR, (2003). Kinetic properties of 'soluble' adenylyl cyclase. Synergism between calcium and bicarbonate. J Biol Chem 278: 15922-15926.
    • (2003) J Biol Chem , vol.278 , pp. 15922-15926
    • Litvin, T.N.1    Kamenetsky, M.2    Zarifyan, A.3    Buck, J.4    Levin, L.R.5
  • 36
    • 70349507172 scopus 로고    scopus 로고
    • Enhancement of BK(Ca) channel activity induced by hydrogen peroxide: Involvement of lipid phosphatase activity of PTEN
    • Liu B, Gan L, Sun X, Zhu Y, Tong Z, Xu H, et al. (2009). Enhancement of BK(Ca) channel activity induced by hydrogen peroxide: involvement of lipid phosphatase activity of PTEN. Biochim Biophys Acta 1788: 2174-2182.
    • (2009) Biochim Biophys Acta , vol.1788 , pp. 2174-2182
    • Liu, B.1    Gan, L.2    Sun, X.3    Zhu, Y.4    Tong, Z.5    Xu, H.6
  • 37
    • 77956363227 scopus 로고    scopus 로고
    • Biphasic effects of H(2)O(2) on BK(Ca) channels
    • Liu B, Sun X, Zhu Y, Gan L, Xu H, Yang X, (2010). Biphasic effects of H(2)O(2) on BK(Ca) channels. Free Radic Res 44: 1004-1012.
    • (2010) Free Radic Res , vol.44 , pp. 1004-1012
    • Liu, B.1    Sun, X.2    Zhu, Y.3    Gan, L.4    Xu, H.5    Yang, X.6
  • 38
    • 80052780146 scopus 로고    scopus 로고
    • Hydrogen peroxide stimulates the epithelial sodium channel through a phosphatidylinositide 3-kinase-dependent pathway
    • Ma HP, (2011). Hydrogen peroxide stimulates the epithelial sodium channel through a phosphatidylinositide 3-kinase-dependent pathway. J Biol Chem 286: 32444-32453.
    • (2011) J Biol Chem , vol.286 , pp. 32444-32453
    • Ma, H.P.1
  • 39
    • 0033831564 scopus 로고    scopus 로고
    • Role of K(V)LQT1 in cyclic adenosine monophosphate-mediated Cl(-) secretion in human airway epithelia
    • Mall M, Wissner A, Schreiber R, Kuehr J, Seydewitz HH, Brandis M, et al. (2000). Role of K(V)LQT1 in cyclic adenosine monophosphate-mediated Cl(-) secretion in human airway epithelia. Am J Respir Cell Mol Biol 23: 283-289.
    • (2000) Am J Respir Cell Mol Biol , vol.23 , pp. 283-289
    • Mall, M.1    Wissner, A.2    Schreiber, R.3    Kuehr, J.4    Seydewitz, H.H.5    Brandis, M.6
  • 40
    • 79957592464 scopus 로고    scopus 로고
    • Functional apical large conductance, Ca2+-activated, and voltage-dependent K+ channels are required for maintenance of airway surface liquid volume
    • Manzanares D, Gonzalez C, Ivonnet P, Chen RS, Valencia-Gattas M, Conner GE, et al. (2011). Functional apical large conductance, Ca2+-activated, and voltage-dependent K+ channels are required for maintenance of airway surface liquid volume. J Biol Chem 286: 19830-19839.
    • (2011) J Biol Chem , vol.286 , pp. 19830-19839
    • Manzanares, D.1    Gonzalez, C.2    Ivonnet, P.3    Chen, R.S.4    Valencia-Gattas, M.5    Conner, G.E.6
  • 41
    • 0030034284 scopus 로고    scopus 로고
    • Hydrogen peroxide increases the intracellular calcium activity in rat mesangial cells in primary culture
    • Meyer TN, Gloy J, Hug MJ, Greger R, Schollmeyer P, Pavenstadt H, (1996). Hydrogen peroxide increases the intracellular calcium activity in rat mesangial cells in primary culture. Kidney Int 49: 388-395.
    • (1996) Kidney Int , vol.49 , pp. 388-395
    • Meyer, T.N.1    Gloy, J.2    Hug, M.J.3    Greger, R.4    Schollmeyer, P.5    Pavenstadt, H.6
  • 42
    • 0023506099 scopus 로고
    • Coupling of voltage-dependent gating and Ba++ block in the high-conductance, Ca++-activated K+ channel
    • Miller C, Latorre R, Reisin I, (1987). Coupling of voltage-dependent gating and Ba++ block in the high-conductance, Ca++-activated K+ channel. J Gen Physiol 90: 427-449.
    • (1987) J Gen Physiol , vol.90 , pp. 427-449
    • Miller, C.1    Latorre, R.2    Reisin, I.3
  • 43
    • 0033811032 scopus 로고    scopus 로고
    • Diverse effects of hydrogen peroxide on cytosolic Ca2+ homeostasis in rat pancreatic beta-cells
    • Nakazaki M, Kakei M, Yaekura K, Koriyama N, Morimitsu S, Ichinari K, et al. (2000). Diverse effects of hydrogen peroxide on cytosolic Ca2+ homeostasis in rat pancreatic beta-cells. Cell Struct Funct 25: 187-193.
    • (2000) Cell Struct Funct , vol.25 , pp. 187-193
    • Nakazaki, M.1    Kakei, M.2    Yaekura, K.3    Koriyama, N.4    Morimitsu, S.5    Ichinari, K.6
  • 44
    • 77955113473 scopus 로고    scopus 로고
    • CFTR-adenylyl cyclase i association responsible for UTP activation of CFTR in well-differentiated primary human bronchial cell cultures
    • Namkung W, Finkbeiner WE, Verkman AS, (2010). CFTR-adenylyl cyclase I association responsible for UTP activation of CFTR in well-differentiated primary human bronchial cell cultures. Mol Biol Cell 21: 2639-2648.
    • (2010) Mol Biol Cell , vol.21 , pp. 2639-2648
    • Namkung, W.1    Finkbeiner, W.E.2    Verkman, A.S.3
  • 45
    • 0023823843 scopus 로고
    • Discrete Ba2+ block as a probe of ion occupancy and pore structure in the high-conductance Ca2+-activated K+ channel
    • Neyton J, Miller C, (1988). Discrete Ba2+ block as a probe of ion occupancy and pore structure in the high-conductance Ca2+-activated K+ channel. J Gen Physiol 92: 569-586.
    • (1988) J Gen Physiol , vol.92 , pp. 569-586
    • Neyton, J.1    Miller, C.2
  • 46
    • 0036788754 scopus 로고    scopus 로고
    • Regulator of G-protein signaling protein 2 modulates purinergic calcium and ciliary beat frequency responses in airway epithelia
    • Nlend MC, Bookman RJ, Conner GE, Salathe M, (2002). Regulator of G-protein signaling protein 2 modulates purinergic calcium and ciliary beat frequency responses in airway epithelia. Am J Respir Cell Mol Biol 27: 436-445.
    • (2002) Am J Respir Cell Mol Biol , vol.27 , pp. 436-445
    • Nlend, M.C.1    Bookman, R.J.2    Conner, G.E.3    Salathe, M.4
  • 47
    • 84891791940 scopus 로고    scopus 로고
    • The IUPHAR/BPS Guide to PHARMACOLOGY: An expert-driven knowledgebase of drug targets and their ligands
    • NC-IUPHAR. (Database Issue)
    • Pawson AJ, Sharman JL, Benson HE, Faccenda E, Alexander SP, Buneman OP, et al.; NC-IUPHAR (2014). The IUPHAR/BPS Guide to PHARMACOLOGY: an expert-driven knowledgebase of drug targets and their ligands. Nucl. Acids Res 42 (Database Issue): D1098-1106.
    • (2014) Nucl. Acids Res , vol.42 , pp. D1098-D1106
    • Pawson, A.J.1    Sharman, J.L.2    Benson, H.E.3    Faccenda, E.4    Alexander, S.P.5    Buneman, O.P.6
  • 48
    • 84889581761 scopus 로고    scopus 로고
    • Epac-inhibitors: Facts and artefacts
    • Rehmann H, (2013). Epac-inhibitors: facts and artefacts. Sci Rep 3: 3032-3037.
    • (2013) Sci Rep , vol.3 , pp. 3032-3037
    • Rehmann, H.1
  • 49
    • 0037303854 scopus 로고    scopus 로고
    • Inhibition of oral peroxidase activity by cigarette smoke: In vivo and in vitro studies
    • Reznick AZ, Klein I, Eiserich JP, Cross CE, Nagler RM, (2003). Inhibition of oral peroxidase activity by cigarette smoke: in vivo and in vitro studies. Free Radic Biol Med 34: 377-384.
    • (2003) Free Radic Biol Med , vol.34 , pp. 377-384
    • Reznick, A.Z.1    Klein, I.2    Eiserich, J.P.3    Cross, C.E.4    Nagler, R.M.5
  • 50
    • 0026940030 scopus 로고
    • H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells
    • Rice KL, Duane PG, Archer SL, Gilboe DP, Niewoehner DE, (1992). H2O2 injury causes Ca(2+)-dependent and -independent hydrolysis of phosphatidylcholine in alveolar epithelial cells. Am J Physiol 263 (4 Pt 1): L430-L438.
    • (1992) Am J Physiol , vol.263 , Issue.4 , pp. L430-L438
    • Rice, K.L.1    Duane, P.G.2    Archer, S.L.3    Gilboe, D.P.4    Niewoehner, D.E.5
  • 51
  • 52
    • 33751185518 scopus 로고    scopus 로고
    • Real-time analysis of cAMP-mediated regulation of ciliary motility in single primary human airway epithelial cells
    • Schmid A, Bai G, Schmid N, Zaccolo M, Ostrowski LE, Conner GE, et al. (2006). Real-time analysis of cAMP-mediated regulation of ciliary motility in single primary human airway epithelial cells. J Cell Sci 119 (Pt 20): 4176-4186.
    • (2006) J Cell Sci , vol.119 , pp. 4176-4186
    • Schmid, A.1    Bai, G.2    Schmid, N.3    Zaccolo, M.4    Ostrowski, L.E.5    Conner, G.E.6
  • 53
    • 77956936528 scopus 로고    scopus 로고
    • Decreased soluble adenylyl cyclase activity in cystic fibrosis is related to defective apical bicarbonate exchange and affects ciliary beat frequency regulation
    • Schmid A, Sutto Z, Schmid N, Novak L, Ivonnet P, Horvath G, et al. (2010). Decreased soluble adenylyl cyclase activity in cystic fibrosis is related to defective apical bicarbonate exchange and affects ciliary beat frequency regulation. J Biol Chem 285: 29998-30007.
    • (2010) J Biol Chem , vol.285 , pp. 29998-30007
    • Schmid, A.1    Sutto, Z.2    Schmid, N.3    Novak, L.4    Ivonnet, P.5    Horvath, G.6
  • 55
    • 77951243499 scopus 로고    scopus 로고
    • Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization
    • Speirs CK, Jernigan KK, Kim SH, Cha YI, Lin F, Sepich DS, et al. (2010). Prostaglandin Gbetagamma signaling stimulates gastrulation movements by limiting cell adhesion through Snai1a stabilization. Development 137: 1327-1337.
    • (2010) Development , vol.137 , pp. 1327-1337
    • Speirs, C.K.1    Jernigan, K.K.2    Kim, S.H.3    Cha, Y.I.4    Lin, F.5    Sepich, D.S.6
  • 56
    • 84901025723 scopus 로고    scopus 로고
    • Mucosal reactive oxygen species are required for antiviral response: Role of Duox in influenza a virus infection
    • Strengert M, Jennings R, Davanture S, Hayes P, Gabriel G, Knaus UG, (2014). Mucosal reactive oxygen species are required for antiviral response: role of Duox in influenza a virus infection. Antioxid Redox Signal 20: 2695-2709.
    • (2014) Antioxid Redox Signal , vol.20 , pp. 2695-2709
    • Strengert, M.1    Jennings, R.2    Davanture, S.3    Hayes, P.4    Gabriel, G.5    Knaus, U.G.6
  • 57
    • 0034640510 scopus 로고    scopus 로고
    • Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin
    • Sun F, Hug MJ, Bradbury NA, Frizzell RA, (2000). Protein kinase A associates with cystic fibrosis transmembrane conductance regulator via an interaction with ezrin. J Biol Chem 275: 14360-14366.
    • (2000) J Biol Chem , vol.275 , pp. 14360-14366
    • Sun, F.1    Hug, M.J.2    Bradbury, N.A.3    Frizzell, R.A.4
  • 58
    • 0036080451 scopus 로고    scopus 로고
    • Expression, localization, and functional evaluation of CFTR in bovine corneal endothelial cells
    • Sun XC, Bonanno JA, (2002). Expression, localization, and functional evaluation of CFTR in bovine corneal endothelial cells. Am J Physiol Cell Physiol 282: C673-C683.
    • (2002) Am J Physiol Cell Physiol , vol.282 , pp. C673-C683
    • Sun, X.C.1    Bonanno, J.A.2
  • 59
    • 26844503126 scopus 로고    scopus 로고
    • Regulation of CFTR channels by HCO(3) - Sensitive soluble adenylyl cyclase in human airway epithelial cells
    • Wang Y, Lam CS, Wu F, Wang W, Duan Y, Huang P, (2005). Regulation of CFTR channels by HCO(3)-sensitive soluble adenylyl cyclase in human airway epithelial cells. Am J Physiol Cell Physiol 289: C1145-C1151.
    • (2005) Am J Physiol Cell Physiol , vol.289 , pp. C1145-C1151
    • Wang, Y.1    Lam, C.S.2    Wu, F.3    Wang, W.4    Duan, Y.5    Huang, P.6
  • 60
    • 57649120773 scopus 로고    scopus 로고
    • Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A
    • Yokoyama U, Minamisawa S, Quan H, Akaike T, Suzuki S, Jin M, et al. (2008). Prostaglandin E2-activated Epac promotes neointimal formation of the rat ductus arteriosus by a process distinct from that of cAMP-dependent protein kinase A. J Biol Chem 283: 28702-28709.
    • (2008) J Biol Chem , vol.283 , pp. 28702-28709
    • Yokoyama, U.1    Minamisawa, S.2    Quan, H.3    Akaike, T.4    Suzuki, S.5    Jin, M.6
  • 61
    • 0036500494 scopus 로고    scopus 로고
    • Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes
    • Zaccolo M, Pozzan T, (2002). Discrete microdomains with high concentration of cAMP in stimulated rat neonatal cardiac myocytes. Science 295: 1711-1715.
    • (2002) Science , vol.295 , pp. 1711-1715
    • Zaccolo, M.1    Pozzan, T.2
  • 62
    • 27644495213 scopus 로고    scopus 로고
    • H2O2 directly activates inositol 1,4,5-trisphosphate receptors in endothelial cells
    • Zheng Y, Shen X, (2005). H2O2 directly activates inositol 1,4,5-trisphosphate receptors in endothelial cells. Redox Rep 10: 29-36.
    • (2005) Redox Rep , vol.10 , pp. 29-36
    • Zheng, Y.1    Shen, X.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.