Cross-talk between Arg methylation and ser phosphorylation modulates apoptosis signal-regulating kinase 1 activation in endothelial cells

Molecular Biology of the Cell

Volumn 27, Issue 8, 2016, Pages 1358-1366

  Chen, Ming ^a,b   Qu, Xiaosheng ^a   Zhang, Zhiqing ^b   Wu, Huayu ^c   Qin, Xia ^c   Li, Fuji ^c   Liu, Zhenfang ^d   Tian, Liyuan ^e   Miao, Jianhua ^a   Shu, Wei ^c  

^a Guangxi Botanical Garden of Medicinal Plants   (China)

^b INSTITUTE OF HEALTH AND ENVIRONMENTAL MEDICINE   (China)

^c GUANGXI MEDICAL UNIVERSITY   (China)

^d FIRST AFFILIATED HOSPITAL OF GUANGXI MEDICAL UNIVERSITY   (China)

^e AIR FORCE GENERAL HOSPITAL   (China)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; ARGININE; HYDROGEN PEROXIDE; PRMT5 PROTEIN; PROTEIN KINASE B; SERINE; UNCLASSIFIED DRUG; VASCULOTROPIN; MAP3K5 PROTEIN, HUMAN; PRMT5 PROTEIN, HUMAN; PROTEIN ARGININE METHYLTRANSFERASE; VASCULOTROPIN A;

AMINO ACID SEQUENCE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; EXPRESSION VECTOR; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; LIQUID CHROMATOGRAPHY; METHYLATION; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN PROCESSING; SIGNAL TRANSDUCTION; TANDEM MASS SPECTROMETRY; UMBILICAL VEIN ENDOTHELIAL CELL; WESTERN BLOTTING; CELL LINE; DRUG EFFECTS; ENDOTHELIUM CELL; GENETICS; METABOLISM; PHOSPHORYLATION;

ARGININE; CELL LINE; ENDOTHELIAL CELLS; ENZYME ACTIVATION; HUMANS; HYDROGEN PEROXIDE; MAP KINASE KINASE KINASE 5; METHYLATION; PHOSPHORYLATION; PROTEIN INTERACTION MAPPING; PROTEIN-ARGININE N-METHYLTRANSFERASES; PROTO-ONCOGENE PROTEINS C-AKT; SERINE; SIGNAL TRANSDUCTION; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84963500411     PISSN: 10591524     EISSN: 19394586     Source Type: Journal    
DOI: 10.1091/mbc.E15-10-0738     Document Type: Article

References (36)

1. Bunkoczi G, Salah E, Filippakopoulos P, Fedorov O, Muller S, Sobott F, Parker SA, Zhang H, Min W, Turk BE, et al. (2007). Structural and functional characterization of the human protein kinase ASK1. Structure 15, 1215-1226.
2. Chen GI, Gingras AC (2007). Affnity-purifcation mass spectrometry (AP-MS) of serine/threonine phosphatases. Methods 42, 298-305.
3. Chen M, Yi B, Sun J (2014). Inhibition of cardiomyocyte hypertrophy by protein arginine methyltransferase 5. J Biol Chem 289, 24325-24335.
4. Cho JH, Lee MK, Yoon KW, Lee J, Cho SG, Choi EJ (2012). Arginine methylation-dependent regulation of ASK1 signaling by PRMT1. Cell Death Differ 19, 859-870.
5. Daitoku H, Hatta M, Matsuzaki H, Aratani S, Ohshima T, Miyagishi M, Na-kajima T, Fukamizu A (2004). Silent information regulator 2 potentiates Foxo1-mediated transcription through its deacetylase activity. Proc Natl Acad Sci USA 101, 10042-10047.
6. Du J, Cai SH, Shi Z, Nagase F (2004). Binding activity of H-Ras is necessary for in vivo inhibition of ASK1 activity. Cell Res 14, 148-154.
7. Fisk JC, Read LK (2011). Protein arginine methylation in parasitic protozoa. Eukaryotic Cell 10, 1013-1022.
8. Fujii K, Goldman EH, Park HR, Zhang L, Chen J, Fu H (2004). Negative control of apoptosis signal-regulating kinase 1 through phosphorylation of Ser-1034. Oncogene 23, 5099-5104.
9. Fujino G, Noguchi T, Matsuzawa A, Yamauchi S, Saitoh M, Takeda K, Ichijo H (2007). Thioredoxin and TRAF family proteins regulate reactive oxygen species-dependent activation of ASK1 through reciprocal modulation of the N-terminal homophilic interaction of ASK1. Mol Cell Biol 27, 8152-8163.
10. Gu JJ, Wang Z, Reeves R, Magnuson NS (2009). PIM1 phosphorylates and negatively regulates ASK1-mediated apoptosis. Oncogene 28, 4261-4271.
11. Harding SJ, Browne GJ, Miller BW, Prigent SA, Dickens M (2010). Activation of ASK1, downstream MAPKK and MAPK isoforms during cardiac ischaemia. Biochim Biophys Acta 1802, 733-740.
12. Hayakawa T, Matsuzawa A, Noguchi T, Takeda K, Ichijo H (2006). The ASK1-MAP kinase pathways in immune and stress responses. Microbes Infect 8, 1098-1107.
13. Huang Y, Wu L, Wu J, Li Y, Hou L (2014). Cellular FLICE-like inhibitory protein protects against cardiac hypertrophy by blocking ASK1/p38 signaling in mice. Mol Cell Biochem 397, 87-95.
14. Hyun MS, Hur JM, Mun YJ, Kim D, Woo WH (2010). BBR induces apoptosis in HepG2 cell through an Akt-ASK1-ROS-p38MAPKs-linked cascade. J Cell Biochem 109, 329-338.
15. Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, Takagi M, Matsumoto K, Miyazono K (1997). Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 275, 90-94.
16. Kadowaki H, Nishitoh H, Urano F, Sadamitsu C, Matsuzawa A, Takeda K, Masutani H, Yodoi J, Urano Y, Nagano T, et al. (2005). Amyloid beta induces neuronal cell death through ROS-mediated ASK1 activation. Cell Death Differ 12, 19-24.
17. Kim AH, Khursigara G, Sun X, Franke TF, Chao MV (2001). Akt phosphory-lates and negatively regulates apoptosis signal-regulating kinase 1. Mol Cell Biol 21, 893-901.
18. Kim SY, Shim JH, Chun E, Lee KY (2012). Reciprocal inhibition between the transforming growth factor-beta-activated kinase 1 (TAK1) and apoptosis signal-regulating kinase 1 (ASK1) mitogen-activated protein kinase kinase kinases and its suppression by TAK1-binding protein 2 (TAB2), an adapter protein for TAK1. J Biol Chem 287, 3381-3391.
19. Kosek D, Kylarova S, Psenakova K, Rezabkova L, Herman P, Vecer J, Obsilova V, Obsil T (2014). Biophysical and structural characterization of the thioredoxin-binding domain of protein kinase ASK1 and its interaction with reduced thioredoxin. J Biol Chem 289, 24463-24474.
20. 2-induced apoptosis via co-modulatory effects on p38-and p42/p44-CCDPK signaling. Acta Pharmacol Sin 23, 45-49.
21. Lu X, Masic A, Li Y, Shin Y, Liu Q, Zhou Y (2010). The PI3K/Akt pathway inhibits infuenza A virus-induced Bax-mediated apoptosis by negatively regulating the JNK pathway via ASK1. J Gen Virol 91, 1439-1449.
22. Machino T, Hashimoto S, Maruoka S, Gon Y, Hayashi S, Mizumura K, Nishitoh H, Ichijo H, Horie T (2003). Apoptosis signal-regulating kinase 1-mediated signaling pathway regulates hydrogen peroxide-induced apoptosis in human pulmonary vascular endothelial cells. Crit Care Med 31, 2776-2781.
23. Matsuzawa A, Saegusa K, Noguchi T, Sadamitsu C, Nishitoh H, Nagai S, Koyasu S, Matsumoto K, Takeda K, Ichijo H (2005). ROS-dependent activation of the TRAF6-ASK1-p38 pathway is selectively required for TLR4-mediated innate immunity. Nat Immunol 6, 587-592.
24. Nako H, Kataoka K, Koibuchi N, Dong YF, Toyama K, Yamamoto E, Yasuda O, Ichijo H, Ogawa H, Kim-Mitsuyama S (2012). Novel mechanism of angiotensin II-induced cardiac injury in hypertensive rats: the critical role of ASK1 and VEGF. Hypertens Res 35, 194-200.
25. Sakamaki J, Daitoku H, Ueno K, Hagiwara A, Yamagata K, Fukamizu A (2011). Arginine methylation of BCL-2 antagonist of cell death (BAD) counteracts its phosphorylation and inactivation by Akt. Proc Natl Acad Sci USA 108, 6085-6090.
26. Seong HA, Jung H, Ichijo H, Ha H (2010). Reciprocal negative regulation of PDK1 and ASK1 signaling by direct interaction and phosphorylation. J Biol Chem 285, 2397-2414.
27. Soga M, Matsuzawa A, Ichijo H (2012). Oxidative stress-induced diseases via the ASK1 signaling pathway. Int J Cell Biol 2012, 439587.
28. Takeda K, Matsuzawa A, Nishitoh H, Ichijo H (2003). Roles of MAPKKK ASK1 in stress-induced cell death. Cell Struct Funct 28, 23-29.
29. 2, and phosphatase inhibitors activate endo-thelial cell ERK1/2 MAP-kinase. Microvasc Res 69, 36-44.
30. Tobiume K, Saitoh M, Ichijo H (2002). Activation of apoptosis signal-regulating kinase 1 by the stress-induced activating phosphorylation of pre-formed oligomer. J Cell Physiol 191, 95-104.
31. Tzeng HE, Tsai CH, Chang ZL, Su CM, Wang SW, Hwang WL, Tang CH (2013). Interleukin-6 induces vascular endothelial growth factor expression and promotes angiogenesis through apoptosis signal-regulating kinase 1 in human osteosarcoma. Biochem Pharmacol 85, 531-540.
32. Wang XS, Diener K, Tan TH, Yao Z (1998). MAPKKK6, a novel mitogen-activated protein kinase kinase kinase, that associates with MAPKKK5. Biochem Biophys Res Commun 253, 33-37.
33. Xie D, Gore C, Zhou J, Pong RC, Zhang H, Yu L, Vessella RL, Min W, Hsieh JT (2009). DAB2IP coordinates both PI3K-Akt and ASK1 pathways for cell survival and apoptosis. Proc Natl Acad Sci USA 106, 19878-19883.
34. Yamagata K, Daitoku H, Takahashi Y, Namiki K, Hisatake K, Kako K, Mukai H, Kasuya Y, Fukamizu A (2008). Arginine methylation of FOXO transcription factors inhibits their phosphorylation by Akt. Mol Cell 32, 221-231.
35. Yokoi T, Fukuo K, Yasuda O, Hotta M, Miyazaki J, Takemura Y, Kawamoto H, Ichijo H, Ogihara T (2006). Apoptosis signal-regulating kinase 1 mediates cellular senescence induced by high glucose in endothelial cells. Diabetes 55, 1660-1665.
36. 2 but not tumor necrosis factor. J Biol Chem 280, 19036-19044.