Interleukin-6 induces vascular endothelial growth factor expression and promotes angiogenesis through apoptosis signal-regulating kinase 1 in human osteosarcoma

Biochemical Pharmacology

Volumn 85, Issue 4, 2013, Pages 531-540

  Tzeng, Huey En ^a,b   Tsai, Chun Hao ^a,c   Chang, Zi Ling ^a   Su, Chen Ming ^a   Wang, Shih Wei ^d   Hwang, Wen Li ^b   Tang, Chih Hsin ^a,e  

^a CHINA MEDICAL UNIVERSITY   (Taiwan)

^b TAICHUNG VETERANS GENERAL HOSPITAL   (Taiwan)

^c CHINA MEDICAL UNIVERSITY HOSPITAL   (Taiwan)

^d MACKAY MEDICAL COLLEGE   (Taiwan)

^e CHINA MEDICAL UNIVERSITY   (Taiwan)

Author keywords

Angiogenesis; ASK1; IL 6; Osteosarcoma; VEGF

Indexed keywords

APOPTOSIS SIGNAL REGULATING KINASE 1; INTERLEUKIN 6; INTERLEUKIN 6 RECEPTOR; MITOGEN ACTIVATED PROTEIN KINASE P38; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR AP 1; VASCULOTROPIN;

ARTICLE; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMAN TISSUE; OSTEOSARCOMA; OSTEOSARCOMA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; TRANSACTIVATION; TUMOR VASCULARIZATION;

ANTIBODIES, MONOCLONAL; BONE NEOPLASMS; CELL DIFFERENTIATION; CELL LINE, TUMOR; ENDOTHELIAL CELLS; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HUMANS; INTERLEUKIN-6; MAP KINASE KINASE KINASE 5; MAP KINASE SIGNALING SYSTEM; NEOVASCULARIZATION, PATHOLOGIC; OSTEOSARCOMA; REAL-TIME POLYMERASE CHAIN REACTION; RECEPTORS, INTERLEUKIN-6; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; STEM CELLS; VASCULAR ENDOTHELIAL GROWTH FACTOR A;

EID: 84872681084     PISSN: 00062952     EISSN: 18732968     Source Type: Journal    
DOI: 10.1016/j.bcp.2012.11.021     Document Type: Article

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