The 5-HT6 receptor antagonist idalopirdine potentiates the effects of acetylcholinesterase inhibition on neuronal network oscillations and extracellular acetylcholine levels in the rat dorsal hippocampus

Neuropharmacology

Volumn 107, Issue , 2016, Pages 351-363

  Herrik, Kjartan F ^a   Mørk, Arne ^a   Richard, Nelly ^a   Bundgaard, Christoffer ^a   Bastlund, Jesper F ^a   De Jong, Inge E M ^a  

^a H LUNDBECK A S   (Denmark)

Author keywords

5 HT6 receptor; Acetylcholine; Alzheimer's disease; Donepezil; Idalopirdine; Neuronal oscillations

Indexed keywords

ACETYLCHOLINE; ACETYLCHOLINESTERASE; DONEPEZIL; IDALOPIRDINE; (2-(6-FLUORO-1H-INDOL-3-YL)-ETHYL)-(3-(2,2,3,3-TETRAFLUOROPROPOXY)BENZYL)AMINE; BENZYLAMINE DERIVATIVE; CHOLINESTERASE INHIBITOR; INDOLE DERIVATIVE; SEROTONIN 6 RECEPTOR; SEROTONIN ANTAGONIST; SEROTONIN RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BRAIN ELECTROPHYSIOLOGY; BRAIN FUNCTION; BRAIN LEVEL; BRAIN REGION; BRAIN STEM; CONTROLLED STUDY; DORSAL HIPPOCAMPUS; DOSE RESPONSE; DRUG EFFECT; DRUG MECHANISM; DRUG POTENTIATION; ENZYME INHIBITION; GAMMA RHYTHM; IN VIVO STUDY; LOCAL FIELD POTENTIAL OSCILLATION; MALE; MICRODIALYSIS; MOUSE; NERVE CELL NETWORK; NONHUMAN; NUCLEUS PONTIS ORALIS; OSCILLATION; PRIORITY JOURNAL; RAT; THETA RHYTHM; ANIMAL; BIOLOGICAL RHYTHM; DRUG EFFECTS; ELECTROENCEPHALOGRAM; EXTRACELLULAR FLUID; HIPPOCAMPUS; METABOLISM; PHYSIOLOGY; SPRAGUE DAWLEY RAT;

ACETYLCHOLINE; ANIMALS; BENZYLAMINES; BIOLOGICAL CLOCKS; BRAIN WAVES; CHOLINESTERASE INHIBITORS; EXTRACELLULAR FLUID; HIPPOCAMPUS; INDOLES; MALE; NERVE NET; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, SEROTONIN; SEROTONIN ANTAGONISTS;

EID: 84962911807     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2016.03.043     Document Type: Article

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