메뉴 건너뛰기




Volumn 46, Issue 1, 1998, Pages 7-12

Pharmacokinetic and pharmacodynamic profile of donepezil HCl following multiple oral doses

Author keywords

Alzheimer's disease; Donepezil; Pharmacodynamics; Pharmacokinetics; Selective acetylcholinesterase inhibitor

Indexed keywords

ACETYLCHOLINESTERASE; CHOLINESTERASE INHIBITOR; DONEPEZIL;

EID: 0032406418     PISSN: 02643774     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2125.1998.0460s1007.x     Document Type: Article
Times cited : (95)

References (17)
  • 2
    • 0025911018 scopus 로고
    • Advances in Alzheimer's disease
    • Katzman R, Saitoh T. Advances in Alzheimer's disease. FASEB J 1991; 5: 278-286.
    • (1991) FASEB J , vol.5 , pp. 278-286
    • Katzman, R.1    Saitoh, T.2
  • 3
    • 0002445652 scopus 로고
    • Therapy of the cognitive deficit in Alzheimer's disease: The cholinergic system
    • eds Becker R, Giacobini E. Boston: Birkhäuser
    • Becker RE. Therapy of the cognitive deficit in Alzheimer's disease: the cholinergic system. In Cholinergic Basis for Alzheimer Therapy, eds Becker R, Giacobini E. Boston: Birkhäuser, 1991: 1-30.
    • (1991) Cholinergic Basis for Alzheimer Therapy , pp. 1-30
    • Becker, R.E.1
  • 4
    • 0000605095 scopus 로고
    • Anticholinesterase agents
    • eds Gilman AG, Rall TW, Nies AS, Taylor P. New York: McGraw-Hill
    • Taylor P. Anticholinesterase agents. In The Pharmacological Basis of Therapeutics, Eighth Edition, eds Gilman AG, Rall TW, Nies AS, Taylor P. New York: McGraw-Hill, 1993: 131-149.
    • (1993) The Pharmacological Basis of Therapeutics, Eighth Edition , pp. 131-149
    • Taylor, P.1
  • 5
    • 0022899577 scopus 로고
    • Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type
    • Summers WK, Majovski LV, Marsh GM, Tachiki K, Kling A. Oral tetrahydroaminoacridine in long-term treatment of senile dementia, Alzheimer type. N Engl J Med 1986; 315: 1241-1245.
    • (1986) N Engl J Med , vol.315 , pp. 1241-1245
    • Summers, W.K.1    Majovski, L.V.2    Marsh, G.M.3    Tachiki, K.4    Kling, A.5
  • 6
    • 0026756286 scopus 로고
    • A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease
    • Davis KL, Thal LJ, Gamzu ER et al. A double-blind, placebo-controlled multicenter study of tacrine for Alzheimer's disease. N Engl J Med 1992; 327: 1253-1259.
    • (1992) N Engl J Med , vol.327 , pp. 1253-1259
    • Davis, K.L.1    Thal, L.J.2    Gamzu, E.R.3
  • 7
    • 0024253376 scopus 로고
    • Long-term administration of oral physostigmine in Alzheimer's disease
    • Stern Y, Sano M, Mayeux R. Long-term administration of oral physostigmine in Alzheimer's disease. Neurology 1988; 38: 1837-1841.
    • (1988) Neurology , vol.38 , pp. 1837-1841
    • Stern, Y.1    Sano, M.2    Mayeux, R.3
  • 8
    • 0028316959 scopus 로고
    • Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease
    • Watkins PB, Zimmerman HJ, Knapp MJ et al. Hepatotoxic effects of tacrine administration in patients with Alzheimer's disease. JAMA 1994; 271: 992-998.
    • (1994) JAMA , vol.271 , pp. 992-998
    • Watkins, P.B.1    Zimmerman, H.J.2    Knapp, M.J.3
  • 9
    • 0026551055 scopus 로고
    • QSAR analysis of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of actylcholinesterase
    • Cardozo MG, Iimura Y, Sugimoto Y, Yamanishi Y, Hopfinger AJ. QSAR analysis of the substituted indanone and benzylpiperidine rings of a series of indanone-benzylpiperidine inhibitors of actylcholinesterase. J Med Chem 1992; 35: 584-589.
    • (1992) J Med Chem , vol.35 , pp. 584-589
    • Cardozo, M.G.1    Iimura, Y.2    Sugimoto, Y.3    Yamanishi, Y.4    Hopfinger, A.J.5
  • 10
    • 0026539070 scopus 로고
    • Conformational analysis and molecular shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase
    • Cardozo MG, Kawai T, Iimura Y, Sugimoto H, Yamanishi Y, Hopfinger AJ. Conformational analysis and molecular shape comparisons of a series of indanone-benzylpiperidine inhibitors of acetylcholinesterase. J Med Chem 1992; 35: 590-601.
    • (1992) J Med Chem , vol.35 , pp. 590-601
    • Cardozo, M.G.1    Kawai, T.2    Iimura, Y.3    Sugimoto, H.4    Yamanishi, Y.5    Hopfinger, A.J.6
  • 11
    • 0026757043 scopus 로고
    • Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride (E2020) and related compounds
    • Sugimoto H, Iimura Y, Yamanishi Y, Yamatsu K. Synthesis and anti-acetylcholinesterase activity of 1-benzyl-4-[(5,6-dimethoxy-1-indanon-2-yl)methyl]piperidine hydrochloride (E2020) and related compounds. Biorg Med Chem Lett 1992; 2: 871-876.
    • (1992) Biorg Med Chem Lett , vol.2 , pp. 871-876
    • Sugimoto, H.1    Iimura, Y.2    Yamanishi, Y.3    Yamatsu, K.4
  • 12
    • 0000396248 scopus 로고
    • Inhibitory action of donepezil, a novel acetylcholinesterase inhibitor, on cholinesterase. Comparison with other inhibitors
    • eds Nagatsu T, Fisher A, Yoshida M. New York: Plenum Press
    • Yamanishi Y, Ogura H, Kosasa T, Araki S, Sawa Y, Yamatsu K. Inhibitory action of donepezil, a novel acetylcholinesterase inhibitor, on cholinesterase. Comparison with other inhibitors. In Basic, Clinical, and Therapeuntic Aspects of Alzheimer's and Parkinson's Diseases, Volume 2, eds Nagatsu T, Fisher A, Yoshida M. New York: Plenum Press, 1990: 409-413.
    • (1990) Basic, Clinical, and Therapeuntic Aspects of Alzheimer's and Parkinson's Diseases , vol.2 , pp. 409-413
    • Yamanishi, Y.1    Ogura, H.2    Kosasa, T.3    Araki, S.4    Sawa, Y.5    Yamatsu, K.6
  • 13
    • 0000557157 scopus 로고
    • E2020 - The pharmacology of a piperidine cholinesterase inhibitor
    • eds Becker R, Giacobini E. Boston: Birkhäuser
    • Rogers SL, Yamansihi Y, Yamatsu K. E2020 - the pharmacology of a piperidine cholinesterase inhibitor. In Cholinergic Basis for Alzheimer Therapy, eds Becker R, Giacobini E. Boston: Birkhäuser, 1991: 314-320.
    • (1991) Cholinergic Basis for Alzheimer Therapy , pp. 314-320
    • Rogers, S.L.1    Yamansihi, Y.2    Yamatsu, K.3
  • 14
    • 0009490250 scopus 로고
    • Behavioral study of E2020, a novel centrally acting acetylcholinesterase inhibitor
    • 27.21
    • Ogura H, Kosasa T, Araki S, Yamanishi Y, Yamatsu K. Behavioral study of E2020, a novel centrally acting acetylcholinesterase inhibitor. Soc Neurosci Abstr 1988; 14: 60 (27.21).
    • (1988) Soc Neurosci Abstr , vol.14 , pp. 60
    • Ogura, H.1    Kosasa, T.2    Araki, S.3    Yamanishi, Y.4    Yamatsu, K.5
  • 15
    • 0032424680 scopus 로고    scopus 로고
    • Pharmacokinetic and pharmacodynamic profile of donepezil HCl following single oral doses
    • Rogers SL, Friedhoff LT. Pharmacokinetic and pharmacodynamic profile of donepezil HCl following single oral doses. Br J Clin Pharmacol 1998; 46 (Suppl. 1): 1-6.
    • (1998) Br J Clin Pharmacol , vol.46 , Issue.SUPPL. 1 , pp. 1-6
    • Rogers, S.L.1    Friedhoff, L.T.2
  • 16
    • 0001346349 scopus 로고
    • Validation and application of an HPLC method for the determination of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine HCl (E2020) in human plasma
    • Lee JW, Rogers SL, Friedhoff IT, Stiles MR, Cooper NM. Validation and application of an HPLC method for the determination of 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine HCl (E2020) in human plasma. Pharm Res 1992; 9: S350.
    • (1992) Pharm Res , vol.9
    • Lee, J.W.1    Rogers, S.L.2    Friedhoff, I.T.3    Stiles, M.R.4    Cooper, N.M.5
  • 17
    • 0344847655 scopus 로고
    • A radioenzyme assay of acetylcholinesterase activity in red blood cells and its correlation with 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine HCl (E2020)
    • Hulse JD, Rogers SL, Friedhorff LT, Sukovaty R, Pedersen JE, Lee JW. A radioenzyme assay of acetylcholinesterase activity in red blood cells and its correlation with 1-benzyl-4-[(5,6-dimethoxy-1-indanon)-2-yl] methyl piperidine HCl (E2020). Pharm Res 1992; 9: S338.
    • (1992) Pharm Res , vol.9
    • Hulse, J.D.1    Rogers, S.L.2    Friedhorff, L.T.3    Sukovaty, R.4    Pedersen, J.E.5    Lee, J.W.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.