Sonic hedgehog is a regulator of extracellular glutamate levels and epilepsy

EMBO Reports

Volumn 17, Issue 5, 2016, Pages 682-694

  Feng, Shengjie ^a,b   Ma, Shaorong ^a,b   Jia, Caixia ^a   Su, Yujuan ^a,b   Yang, Shenglian ^a   Zhou, Kechun ^a   Liu, Yani ^c   Cheng, Ju ^a,b   Lu, Dunguo ^a   Fan, Liu ^a   Wang, Yizheng ^a  

^a Chinese Academy of Sciences   (China)

^b UNIVERSITY OF CHINESE ACADEMY OF SCIENCES   (China)

^c BEIJING INSTITUTE OF MICROBIOLOGY AND EPIDEMIOLOGY   (China)

Author keywords

Epilepsy; extracellular glutamate; glutamate transporter; neuronal activity; sonic hedgehog

Indexed keywords

CALCIUM ION; DIAZEPAM; GLUTAMATE TRANSPORTER; GLUTAMIC ACID; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN ALPHA; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PROTEIN PATCHED 1; SMOOTHENED PROTEIN; SONIC HEDGEHOG PROTEIN; TRANSCRIPTION FACTOR GLI1; TRANSCRIPTION FACTOR GLI2; UNCLASSIFIED DRUG; CALCIUM;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BRAIN CORTEX; CALCIUM CELL LEVEL; CONTROLLED STUDY; DOWN REGULATION; EPILEPSY; EPILEPTIC DISCHARGE; EPILEPTIC STATE; EPILEPTOGENESIS; EXTRACELLULAR SPACE; HIPPOCAMPUS; IN VIVO STUDY; KINDLING; MALE; MOUSE; NERVE CELL CULTURE; NERVE EXCITABILITY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN SECRETION; SEIZURE THRESHOLD; SIGNAL TRANSDUCTION; UPREGULATION; ANIMAL; DISEASE MODEL; KNOCKOUT MOUSE; METABOLISM; NERVE CELL; PYRAMIDAL NERVE CELL; RAT;

ANIMALS; CALCIUM; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; EPILEPSY; EXTRACELLULAR SPACE; GLUTAMIC ACID; GTP-BINDING PROTEIN ALPHA SUBUNITS, GI-GO; HEDGEHOG PROTEINS; HIPPOCAMPUS; MALE; MICE; MICE, KNOCKOUT; NEURONS; PYRAMIDAL CELLS; RATS; SIGNAL TRANSDUCTION; ZINC FINGER PROTEIN GLI1;

EID: 84962878674     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.15252/embr.201541569     Document Type: Article

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