Regulation of epileptiform activity by two distinct subtypes of extrasynaptic GABAA receptors

Molecular Brain

Volumn 6, Issue 1, 2013, Pages

  Sun, Yajie ^a   Wu, Zheng ^a,b   Kong, Shuzhen ^a   Jiang, Dongyun ^b   Pitre, Anar ^b   Wang, Yun ^a   Chen, Gong ^b  

^a FUDAN UNIVERSITY   (China)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

subunit; Epileptiform activity; Epileptogenesis; Extrasynaptic GABAA receptor, 5 subunit; Seizure behavior; THIP; Tonic inhibition

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; GABOXADOL; 4 AMINOBUTYRIC ACID; BENZOTHIADIAZINE DERIVATIVE; CYCLOTHIAZIDE; ISOXAZOLE DERIVATIVE;

ANIMAL CELL; ANIMAL CELL CULTURE; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; DNA TRANSFECTION; EMBRYO; EPILEPTIC DISCHARGE; EPILEPTIFORM BURST ACTIVITY; EPILEPTOGENESIS; GABAERGIC SYNAPTIC TRANSMISSION; GENE OVEREXPRESSION; HIPPOCAMPUS; IN VITRO STUDY; IN VIVO STUDY; MALE; NERVE CELL; NERVE POTENTIAL; NERVOUS SYSTEM ELECTROPHYSIOLOGY; NERVOUS SYSTEM PARAMETERS; NONHUMAN; PRIORITY JOURNAL; RAT; SEIZURE; SYNAPTIC TRANSMISSION; ANIMAL; CELL CULTURE; CHANNEL GATING; DRUG EFFECTS; EPILEPSY; FEMALE; HEK293 CELL LINE; HUMAN; INHIBITORY POSTSYNAPTIC POTENTIAL; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; SPRAGUE DAWLEY RAT; SYNAPSE;

RATTUS;

ANIMALS; BENZOTHIADIAZINES; CELLS, CULTURED; EPILEPSY; FEMALE; GAMMA-AMINOBUTYRIC ACID; HEK293 CELLS; HIPPOCAMPUS; HUMANS; INHIBITORY POSTSYNAPTIC POTENTIALS; ION CHANNEL GATING; ISOXAZOLES; MALE; NEURONS; RATS; RATS, SPRAGUE-DAWLEY; RECEPTORS, GABA-A; SEIZURES; SYNAPSES; SYNAPTIC TRANSMISSION;

EID: 84876793409     PISSN: None     EISSN: 17566606     Source Type: Journal    
DOI: 10.1186/1756-6606-6-21     Document Type: Article

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