Virulent Mycobacterium bovis Beijing strain activates the NLRP7 inflammasome in THP-1 macrophages

PLoS ONE

Volumn 11, Issue 4, 2016, Pages

  Zhou, Yang ^a   Shah, Syed Zahid Ali ^a   Yang, Lifeng ^a   Zhang, Zhongqiu ^b   Zhou, Xiangmei ^a   Zhao, Deming ^a  

^a CHINA AGRICULTURAL UNIVERSITY   (China)

^b AGRO ENVIRONMENTAL PROTECTION INSTITUTE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; INTERLEUKIN 1BETA CONVERTING ENZYME; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; NLRP7 INFLAMMASOME; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; MESSENGER RNA; NLRP7 PROTEIN, HUMAN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; TUMOR NECROSIS FACTOR;

ANIMAL TISSUE; ARTICLE; BACTERIAL STRAIN; BACTERIAL VIRULENCE; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOKINE RELEASE; ENZYME ACTIVATION; GENE EXPRESSION; MACROPHAGE; MYCOBACTERIUM BOVIS; NONHUMAN; NUCLEOTIDE BINDING SITE; PROTEIN DOMAIN; PROTEIN EXPRESSION; PYROPTOSIS; THP 1 MACROPHAGE; UPREGULATION; BIOSYNTHESIS; CELL CULTURE; CELL LINE; GENE EXPRESSION REGULATION; GENE SILENCING; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; PATHOGENICITY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; CASPASE 1; CELL LINE; CELLS, CULTURED; CHEMOKINE CCL3; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; INFLAMMASOMES; INTERLEUKIN-18; INTERLEUKIN-1BETA; MACROPHAGES; MYCOBACTERIUM BOVIS; PYROPTOSIS; RNA, MESSENGER; RNA, SMALL INTERFERING; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84962858004     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0152853     Document Type: Article

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