Core Circadian Clock Genes Regulate Leukemia Stem Cells in AML

Cell

Volumn 165, Issue 2, 2016, Pages 303-316

  Puram, Rishi V ^a,b   Kowalczyk, Monika S ^b   De Boer, Carl G ^b   Schneider, Rebekka K ^a   Miller, Peter G ^a   McConkey, Marie ^a   Tothova, Zuzana ^a,b   Tejero, Héctor ^c   Heckl, Dirk ^a,d   Järås, Marcus ^a,e   Chen, Michelle C ^a   Li, Hubo ^a   Tamayo, Alfred ^a   Cowley, Glenn S ^b   Rozenblatt Rosen, Orit ^b   Al Shahrour, Fatima ^a,c   Regev, Aviv ^b,f,g   Ebert, Benjamin L ^a,b  

^a HARVARD MEDICAL SCHOOL   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c Centro Nacional de Investigaciones Oncológicas   (Spain)

^d HANNOVER MEDICAL SCHOOL   (Germany)

^e LUND UNIVERSITY   (Sweden)

^f MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^g HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TRANSCRIPTION FACTOR ARNTL; TRANSCRIPTION FACTOR CLOCK; ARNTL PROTEIN, HUMAN; ARNTL PROTEIN, MOUSE; CLOCK PROTEIN, HUMAN; SMALL INTERFERING RNA;

ACUTE MYELOBLASTIC LEUKEMIA; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER STEM CELL; CELL CYCLE PROGRESSION; CELL DIFFERENTIATION; CELL GROWTH; CELL PROLIFERATION; CIRCADIAN RHYTHM; CONTROLLED STUDY; GENE CONTROL; HEMATOPOIESIS; IN VITRO STUDY; IN VIVO STUDY; KNOCKOUT GENE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RNA INTERFERENCE; ACUTE MYELOID LEUKEMIA; ANIMAL; C57BL MOUSE; DISEASE MODEL; GENE INACTIVATION; GENETICS; HUMAN; METABOLISM; PATHOLOGY;

ANIMALS; ARNTL TRANSCRIPTION FACTORS; CIRCADIAN RHYTHM; CLOCK PROTEINS; DISEASE MODELS, ANIMAL; GENE KNOCKOUT TECHNIQUES; HEMATOPOIESIS; HUMANS; LEUKEMIA, MYELOID, ACUTE; MICE; MICE, INBRED C57BL; NEOPLASTIC STEM CELLS; RNA INTERFERENCE; RNA, SMALL INTERFERING;

EID: 84962852337     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2016.03.015     Document Type: Article

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