-
1
-
-
0034537290
-
Autophagy as a regulated pathway of cellular degradation
-
Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation. Science 2000;290:1717–21.
-
(2000)
Science
, vol.290
, pp. 1717-1721
-
-
Klionsky, D.J.1
Emr, S.D.2
-
2
-
-
23644443068
-
The significance of autophagy in cancer
-
Ng G, Huang J. The significance of autophagy in cancer. Mol Carcinog 2005;43:183–7.
-
(2005)
Mol Carcinog
, vol.43
, pp. 183-187
-
-
Ng, G.1
Huang, J.2
-
3
-
-
77951228508
-
Hypoxia-induced autophagy: cell death or cell survival?
-
Mazure NM, Pouysségur J. Hypoxia-induced autophagy: cell death or cell survival? Curr Opin Cell Biol 2010;22:177–80.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 177-180
-
-
Mazure, N.M.1
Pouysségur, J.2
-
4
-
-
84903128568
-
Autophagy inhibits chemotherapy-induced apoptosis through downregulating Bad and Bim in hepatocellular carcinoma cells
-
Zhou Y, Sun K, Ma Y, Yang H, Zhang Y, Kong X, Wei L. Autophagy inhibits chemotherapy-induced apoptosis through downregulating Bad and Bim in hepatocellular carcinoma cells. Sci Rep 2014;4:5382.
-
(2014)
Sci Rep
, vol.4
, pp. 5382
-
-
Zhou, Y.1
Sun, K.2
Ma, Y.3
Yang, H.4
Zhang, Y.5
Kong, X.6
Wei, L.7
-
5
-
-
57449121645
-
The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells
-
Lu Z, Luo RZ, Lu Y, et al. The tumor suppressor gene ARHI regulates autophagy and tumor dormancy in human ovarian cancer cells. J Clin Invest 2008;118:3917–29.
-
(2008)
J Clin Invest
, vol.118
, pp. 3917-3929
-
-
Lu, Z.1
Luo, R.Z.2
Lu, Y.3
-
6
-
-
84892380757
-
Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases
-
Choi EJ, Cho BJ, Lee DJ, Hwang YH, Chun SH, Kim HH, Kim IA. Enhanced cytotoxic effect of radiation and temozolomide in malignant glioma cells: targeting PI3K-AKT-mTOR signaling, HSP90 and histone deacetylases. BMC Cancer 2014;14:17.
-
(2014)
BMC Cancer
, vol.14
, pp. 17
-
-
Choi, E.J.1
Cho, B.J.2
Lee, D.J.3
Hwang, Y.H.4
Chun, S.H.5
Kim, H.H.6
Kim, I.A.7
-
7
-
-
84864334967
-
Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo
-
Botta G, Passaro C, Libertini S, Abagnale A, Barbato S, Maione AS, Hallden G, Beguinot F, Formisano P, Portella G. Inhibition of autophagy enhances the effects of E1A-defective oncolytic adenovirus dl922-947 against glioma cells in vitro and in vivo. Hum Gene Ther 2012;23:623–34.
-
(2012)
Hum Gene Ther
, vol.23
, pp. 623-634
-
-
Botta, G.1
Passaro, C.2
Libertini, S.3
Abagnale, A.4
Barbato, S.5
Maione, A.S.6
Hallden, G.7
Beguinot, F.8
Formisano, P.9
Portella, G.10
-
8
-
-
77951214016
-
Mammalian autophagy: core molecular machinery and signaling regulation
-
Yang Z, Klionsky DJ. Mammalian autophagy: core molecular machinery and signaling regulation. Curr Opin Cell Biol 2010;22:124–31.
-
(2010)
Curr Opin Cell Biol
, vol.22
, pp. 124-131
-
-
Yang, Z.1
Klionsky, D.J.2
-
9
-
-
48649098125
-
Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia
-
Cario G, Fetz A, Bretscher C, Möricke A, Schrauder A, Stanulla M, Schrappe M. Initial leukemic gene expression profiles of patients with poor in vivo prednisone response are similar to those of blasts persisting under prednisone treatment in childhood acute lymphoblastic leukemia. Ann Hematol 2008;87:709–16.
-
(2008)
Ann Hematol
, vol.87
, pp. 709-716
-
-
Cario, G.1
Fetz, A.2
Bretscher, C.3
Möricke, A.4
Schrauder, A.5
Stanulla, M.6
Schrappe, M.7
-
10
-
-
84882239458
-
User-friendly solution for microarray quality control and pre-processing on ArrayAnalysis.org
-
(Published online)
-
Eijssen LM, Jaillard M, Adriaens ME, Gaj S, de Groot PJ, Müller M, Evelo CT. User-friendly solution for microarray quality control and pre-processing on ArrayAnalysis.org. Nucleic Acids Res 2013;41:W71–76 (Published online).
-
(2013)
Nucleic Acids Res
, vol.41
, pp. 71-76
-
-
Eijssen, L.M.1
Jaillard, M.2
Adriaens, M.E.3
Gaj, S.4
de Groot, P.J.5
Müller, M.6
Evelo, C.T.7
-
11
-
-
84896390397
-
Autophagy and apoptosis: where do they meet?
-
Mukhopadhyay S, Panda PK, Sinha N, Das DN, Bhutia SK. Autophagy and apoptosis: where do they meet? Apoptosis 2014;19:555–66.
-
(2014)
Apoptosis
, vol.19
, pp. 555-566
-
-
Mukhopadhyay, S.1
Panda, P.K.2
Sinha, N.3
Das, D.N.4
Bhutia, S.K.5
-
12
-
-
67549135481
-
Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy
-
Laane E, Tamm KP, Buentke E, et al. Cell death induced by dexamethasone in lymphoid leukemia is mediated through initiation of autophagy. Cell Death Differ 2009;16:1018–29.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1018-1029
-
-
Laane, E.1
Tamm, K.P.2
Buentke, E.3
-
13
-
-
84859778293
-
mTOR signaling in growth control and disease
-
Laplante M, Sabatini DM. mTOR signaling in growth control and disease. Cell 2012;149:274–93.
-
(2012)
Cell
, vol.149
, pp. 274-293
-
-
Laplante, M.1
Sabatini, D.M.2
-
14
-
-
84891851458
-
MEK in cancer and cancer therapy
-
Neuzillet C, Tijeras-Raballand A, de Mestier L, Cros J, Faivre S, Raymond E. MEK in cancer and cancer therapy. Pharmacol Ther 2014;141:160–71.
-
(2014)
Pharmacol Ther
, vol.141
, pp. 160-171
-
-
Neuzillet, C.1
Tijeras-Raballand, A.2
de Mestier, L.3
Cros, J.4
Faivre, S.5
Raymond, E.6
-
15
-
-
34249995742
-
ERK1/2 phosphorylation is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia
-
Gregorj C, Ricciardi MR, Petrucci MT, et al. ERK1/2 phosphorylation is an independent predictor of complete remission in newly diagnosed adult acute lymphoblastic leukemia. Blood 2007;109:5473–6.
-
(2007)
Blood
, vol.109
, pp. 5473-5476
-
-
Gregorj, C.1
Ricciardi, M.R.2
Petrucci, M.T.3
-
16
-
-
17444431201
-
Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis
-
Ma L, Chen Z, Erdjument-Bromage H, Tempst P, Pandolfi PP. Phosphorylation and functional inactivation of TSC2 by Erk implications for tuberous sclerosis and cancer pathogenesis. Cell 2005;121:179–93.
-
(2005)
Cell
, vol.121
, pp. 179-193
-
-
Ma, L.1
Chen, Z.2
Erdjument-Bromage, H.3
Tempst, P.4
Pandolfi, P.P.5
-
17
-
-
0043127125
-
Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling
-
Inoki K, Li Y, Xu T, Guan KL. Rheb GTPase is a direct target of TSC2 GAP activity and regulates mTOR signaling. Genes Dev 2003;17:1829–34.
-
(2003)
Genes Dev
, vol.17
, pp. 1829-1834
-
-
Inoki, K.1
Li, Y.2
Xu, T.3
Guan, K.L.4
-
18
-
-
67349217986
-
Molecular mechanisms of mTOR-mediated translational control
-
Ma XM, Blenis J. Molecular mechanisms of mTOR-mediated translational control. Nat Rev Mol Cell Biol 2009;10:307–18.
-
(2009)
Nat Rev Mol Cell Biol
, vol.10
, pp. 307-318
-
-
Ma, X.M.1
Blenis, J.2
-
19
-
-
0037236662
-
Regulation of channels by the serum and glucocorticoid-inducible kinase - implications for transport, excitability and cell proliferation
-
Lang F, Henke G, Embark HM, Waldegger S, Palmada M, Böhmer C, Vallon V. Regulation of channels by the serum and glucocorticoid-inducible kinase - implications for transport, excitability and cell proliferation. Cell Physiol Biochem 2003;13:41–50.
-
(2003)
Cell Physiol Biochem
, vol.13
, pp. 41-50
-
-
Lang, F.1
Henke, G.2
Embark, H.M.3
Waldegger, S.4
Palmada, M.5
Böhmer, C.6
Vallon, V.7
-
20
-
-
84895867327
-
The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase
-
(Published online)
-
Mori S, Nada S, Kimura H, Tajima S, Takahashi Y, Kitamura A, Oneyama C, Okada M. The mTOR pathway controls cell proliferation by regulating the FoxO3a transcription factor via SGK1 kinase. PLoS ONE 2014;9:e88891 (Published online).
-
(2014)
PLoS ONE
, vol.9
-
-
Mori, S.1
Nada, S.2
Kimura, H.3
Tajima, S.4
Takahashi, Y.5
Kitamura, A.6
Oneyama, C.7
Okada, M.8
-
21
-
-
84871997810
-
Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy
-
Andres-Mateos E, Brinkmeier H, Burks TN, et al. Activation of serum/glucocorticoid-induced kinase 1 (SGK1) is important to maintain skeletal muscle homeostasis and prevent atrophy. EMBO Mol Med 2013;5:80–91.
-
(2013)
EMBO Mol Med
, vol.5
, pp. 80-91
-
-
Andres-Mateos, E.1
Brinkmeier, H.2
Burks, T.N.3
-
22
-
-
65249176304
-
ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery
-
Jung CH, Jun CB, Ro SH, Kim YM, Otto NM, Cao J, Kundu M, Kim DH. ULK-Atg13-FIP200 complexes mediate mTOR signaling to the autophagy machinery. Mol Biol Cell 2009;20:1992–2003.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1992-2003
-
-
Jung, C.H.1
Jun, C.B.2
Ro, S.H.3
Kim, Y.M.4
Otto, N.M.5
Cao, J.6
Kundu, M.7
Kim, D.H.8
-
23
-
-
65249119430
-
Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy
-
Hosokawa N, Hara T, Kaizuka T, et al. Nutrient-dependent mTORC1 association with the ULK1-Atg13-FIP200 complex required for autophagy. Mol Biol Cell 2009;20:1981–91.
-
(2009)
Mol Biol Cell
, vol.20
, pp. 1981-1991
-
-
Hosokawa, N.1
Hara, T.2
Kaizuka, T.3
-
24
-
-
67650745428
-
PUMA- and Bax-induced autophagy contributes to apoptosis
-
Yee KS, Wilkinson S, James J, Ryan KM, Vousden KH. PUMA- and Bax-induced autophagy contributes to apoptosis. Cell Death Differ 2009;16:1135–45.
-
(2009)
Cell Death Differ
, vol.16
, pp. 1135-1145
-
-
Yee, K.S.1
Wilkinson, S.2
James, J.3
Ryan, K.M.4
Vousden, K.H.5
-
25
-
-
79952102958
-
Bfl-1/A1 acts as a negative regulator of autophagy in mycobacteria infected macrophages
-
Kathania M, Raje CI, Raje M, Dutta RK, Majumdar S. Bfl-1/A1 acts as a negative regulator of autophagy in mycobacteria infected macrophages. Int J Biochem Cell Biol 2011;43:573–85.
-
(2011)
Int J Biochem Cell Biol
, vol.43
, pp. 573-585
-
-
Kathania, M.1
Raje, C.I.2
Raje, M.3
Dutta, R.K.4
Majumdar, S.5
-
26
-
-
77649213702
-
Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia
-
Stam RW, Den Boer ML, Schneider P, et al. Association of high-level MCL-1 expression with in vitro and in vivo prednisone resistance in MLL-rearranged infant acute lymphoblastic leukemia. Blood 2010;115:1018–25.
-
(2010)
Blood
, vol.115
, pp. 1018-1025
-
-
Stam, R.W.1
Den Boer, M.L.2
Schneider, P.3
-
27
-
-
78751621004
-
MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner
-
Germain M, Nguyen AP, Le Grand JN, Arbour N, Vanderluit JL, Park DS, Opferman JT, Slack RS. MCL-1 is a stress sensor that regulates autophagy in a developmentally regulated manner. EMBO J 2011;30:395–407.
-
(2011)
EMBO J
, vol.30
, pp. 395-407
-
-
Germain, M.1
Nguyen, A.P.2
Le Grand, J.N.3
Arbour, N.4
Vanderluit, J.L.5
Park, D.S.6
Opferman, J.T.7
Slack, R.S.8
-
28
-
-
77949270765
-
S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3
-
Ghavami S, Eshragi M, Ande SR, Chazin WJ, Klonisch T, Halayako AJ, McNeill KD, Hashemi M, Kerkhoff C, Los M. S100A8/A9 induces autophagy and apoptosis via ROS-mediated cross-talk between mitochondria and lysosomes that involves BNIP3. Cell Res 2010;20:314–31.
-
(2010)
Cell Res
, vol.20
, pp. 314-331
-
-
Ghavami, S.1
Eshragi, M.2
Ande, S.R.3
Chazin, W.J.4
Klonisch, T.5
Halayako, A.J.6
McNeill, K.D.7
Hashemi, M.8
Kerkhoff, C.9
Los, M.10
-
29
-
-
84901356565
-
S100A8 contributes to drug resistance by promoting autophagy in leukemia cells
-
Yang M, Zeng P, Kang R, Yu Y, Yang L, Tang D, Cao L. S100A8 contributes to drug resistance by promoting autophagy in leukemia cells. PLoS ONE 2010;9:e97242.
-
(2010)
PLoS ONE
, vol.9
-
-
Yang, M.1
Zeng, P.2
Kang, R.3
Yu, Y.4
Yang, L.5
Tang, D.6
Cao, L.7
-
30
-
-
84880331368
-
ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase
-
Russell RC, Tian Y, Yuan H, Park HW, Chang YY, Kim J, Kim H, Neufeld TP, Dilin A, Guan KL. ULK1 induces autophagy by phosphorylating Beclin-1 and activating VPS34 lipid kinase. Nat Cell Biol 2013;15:741–50.
-
(2013)
Nat Cell Biol
, vol.15
, pp. 741-750
-
-
Russell, R.C.1
Tian, Y.2
Yuan, H.3
Park, H.W.4
Chang, Y.Y.5
Kim, J.6
Kim, H.7
Neufeld, T.P.8
Dilin, A.9
Guan, K.L.10
-
31
-
-
0033978633
-
Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells
-
Petiot A, Ogier-Denis E, Blommaart EF, Meijer AJ, Codogno P. Distinct classes of phosphatidylinositol 3′-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells. J Biol Chem 2000;275:992–8.
-
(2000)
J Biol Chem
, vol.275
, pp. 992-998
-
-
Petiot, A.1
Ogier-Denis, E.2
Blommaart, E.F.3
Meijer, A.J.4
Codogno, P.5
-
32
-
-
83455225635
-
The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis
-
Rubinstein AD, Eisenstein M, Ber Y, Bialik S, Kimchi A. The autophagy protein Atg12 associates with antiapoptotic Bcl-2 family members to promote mitochondrial apoptosis. Mol Cell 2011;44:698–709.
-
(2011)
Mol Cell
, vol.44
, pp. 698-709
-
-
Rubinstein, A.D.1
Eisenstein, M.2
Ber, Y.3
Bialik, S.4
Kimchi, A.5
-
33
-
-
77957189194
-
α-Synuclein impairs macroautophagy: implications for Parkinson's disease
-
Winslow AR, Chen CW, Corrochano S, et al. α-Synuclein impairs macroautophagy: implications for Parkinson's disease. J Cell Biol 2010;190:1023–37.
-
(2010)
J Cell Biol
, vol.190
, pp. 1023-1037
-
-
Winslow, A.R.1
Chen, C.W.2
Corrochano, S.3
-
34
-
-
82555187810
-
Image-based genome-wide siRNA screen identifies selective autophagy factors
-
Orvedahl A, Sumpter R Jr, Xiao G, et al. Image-based genome-wide siRNA screen identifies selective autophagy factors. Nature 2011;480:113–7.
-
(2011)
Nature
, vol.480
, pp. 113-117
-
-
Orvedahl, A.1
Sumpter, R.2
Xiao, G.3
-
35
-
-
80054758176
-
Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation
-
Chua CE, Gan BQ, Tang BL. Involvement of members of the Rab family and related small GTPases in autophagosome formation and maturation. Cell Mol Life Sci 2011;68:3349–58.
-
(2011)
Cell Mol Life Sci
, vol.68
, pp. 3349-3358
-
-
Chua, C.E.1
Gan, B.Q.2
Tang, B.L.3
-
36
-
-
77951171023
-
Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance
-
Bonapace L, Bornhauser BC, Schmitz M, Cario G, Ziegler U, Niggli FK, Schafer BW, Schrappe M, Stanulla M, Bourguin JP. Induction of autophagy-dependent necroptosis is required for childhood acute lymphoblastic leukemia cells to overcome glucocorticoid resistance. J Clin Invest 2010;120:1310–23.
-
(2010)
J Clin Invest
, vol.120
, pp. 1310-1323
-
-
Bonapace, L.1
Bornhauser, B.C.2
Schmitz, M.3
Cario, G.4
Ziegler, U.5
Niggli, F.K.6
Schafer, B.W.7
Schrappe, M.8
Stanulla, M.9
Bourguin, J.P.10
-
37
-
-
65349114832
-
Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia
-
Carazzola M, Cisterne A, Thien M, Hewson J, Baraz R, Bradstock KF, Bendall LJ. Potentiating effects of RAD001 (Everolimus) on vincristine therapy in childhood acute lymphoblastic leukemia. Blood 2009;113:3297–306.
-
(2009)
Blood
, vol.113
, pp. 3297-3306
-
-
Carazzola, M.1
Cisterne, A.2
Thien, M.3
Hewson, J.4
Baraz, R.5
Bradstock, K.F.6
Bendall, L.J.7
|