Pregnancy and lactation differentially modify the transcriptional regulation of steroidogenic enzymes through DNA methylation mechanisms in the hippocampus of aged rats

Molecular and Cellular Endocrinology

Volumn 429, Issue , 2016, Pages 73-83

  Rossetti, María F ^a   Varayoud, Jorgelina ^a   Lazzarino, Gisela P ^a   Luque, Enrique H ^a   Ramos, Jorge G ^a  

^a UNIVERSIDAD NACIONAL DEL LITORAL   (Argentina)

Author keywords

Aging; DNA methylation; Hippocampus; Maternal experience; Neurosteroidogenic enzymes

Indexed keywords

ALDOSTERONE SYNTHASE; AROMATASE; BRAIN DERIVED NEUROTROPHIC FACTOR; CHOLESTEROL MONOOXYGENASE (SIDE CHAIN CLEAVING); SPINOPHILIN; STEROID 5ALPHA REDUCTASE 1; SYNAPTOPHYSIN; ACTIN BINDING PROTEIN; MESSENGER RNA; NERVE PROTEIN; NEURABIN; STEROID;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DNA METHYLATION; ENZYME MECHANISM; FEMALE; HIPPOCAMPAL CA1 REGION; LACTATION; MIDDLE AGED; MULTIPARA; NONHUMAN; NULLIPARA; PREGNANCY; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN EXPRESSION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; STEROIDOGENESIS; TRANSCRIPTION REGULATION; YOUNG ADULT; ANIMAL; BIOSYNTHESIS; COMPUTER SIMULATION; ENZYMOLOGY; GENE EXPRESSION REGULATION; GENETICS; HIPPOCAMPUS; METABOLISM; REAL TIME POLYMERASE CHAIN REACTION; WISTAR RAT;

AGING; ANIMALS; AROMATASE; BIOSYNTHETIC PATHWAYS; BRAIN-DERIVED NEUROTROPHIC FACTOR; CHOLESTEROL SIDE-CHAIN CLEAVAGE ENZYME; COMPUTER SIMULATION; DNA METHYLATION; FEMALE; GENE EXPRESSION REGULATION; HIPPOCAMPUS; LACTATION; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; PREGNANCY; PROMOTER REGIONS, GENETIC; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; RNA, MESSENGER; STEROIDS; SYNAPTOPHYSIN;

EID: 84962748653     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2016.03.037     Document Type: Article

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