-
1
-
-
84867637631
-
The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells
-
Šemeláková M., Mikeš J., Jendželovský R., Fedoročko P. The pro-apoptotic and anti-invasive effects of hypericin-mediated photodynamic therapy are enhanced by hyperforin or aristoforin in HT-29 colon adenocarcinoma cells. J. Photochem. Photobiol. B: Biol. 2012, 117:115-125.
-
(2012)
J. Photochem. Photobiol. B: Biol.
, vol.117
, pp. 115-125
-
-
Šemeláková, M.1
Mikeš, J.2
Jendželovský, R.3
Fedoročko, P.4
-
2
-
-
0034093844
-
Apoptotic and anti-apoptotic signaling pathways induced by photodynamic therapy with hypericin
-
Agostinis P., Assefa Z., Vantieghem A., Vandenheede J.R., Merlevede W., De Witte P. Apoptotic and anti-apoptotic signaling pathways induced by photodynamic therapy with hypericin. Adv. Enzyme Regul. 2000, 40:157-182.
-
(2000)
Adv. Enzyme Regul.
, vol.40
, pp. 157-182
-
-
Agostinis, P.1
Assefa, Z.2
Vantieghem, A.3
Vandenheede, J.R.4
Merlevede, W.5
De Witte, P.6
-
3
-
-
33750697260
-
Hypericin-induced photocytotoxicity is connected with G2/M arrest in HT-29 and S-phase arrest in U937 cells
-
Sacková V., Fedorocko P., Szilárdiová B., Mikes J., Kleban J. Hypericin-induced photocytotoxicity is connected with G2/M arrest in HT-29 and S-phase arrest in U937 cells. Photochem. Photobiol. 2006, 82:1285-1291.
-
(2006)
Photochem. Photobiol.
, vol.82
, pp. 1285-1291
-
-
Sacková, V.1
Fedorocko, P.2
Szilárdiová, B.3
Mikes, J.4
Kleban, J.5
-
4
-
-
34447121986
-
Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin
-
Mikes J., Kleban J., Sacková V., Horváth V., Jamborová E., Vaculová A., Kozubík A., Hofmanová J., Fedorocko P. Necrosis predominates in the cell death of human colon adenocarcinoma HT-29 cells treated under variable conditions of photodynamic therapy with hypericin. Photochem. Photobiol. Sci. 2007, 6:758-766.
-
(2007)
Photochem. Photobiol. Sci.
, vol.6
, pp. 758-766
-
-
Mikes, J.1
Kleban, J.2
Sacková, V.3
Horváth, V.4
Jamborová, E.5
Vaculová, A.6
Kozubík, A.7
Hofmanová, J.8
Fedorocko, P.9
-
5
-
-
84941744911
-
Alterations in dysadherin expression and F-actin reorganization: a possible mechanism of hypericin-mediated photodynamic therapy in colon adenocarcinoma cells
-
Süloğlu A.K., Selmanoğlu G., Akay M.T. Alterations in dysadherin expression and F-actin reorganization: a possible mechanism of hypericin-mediated photodynamic therapy in colon adenocarcinoma cells. Cytotechnology 2015, 67:311-330.
-
(2015)
Cytotechnology
, vol.67
, pp. 311-330
-
-
Süloğlu, A.K.1
Selmanoğlu, G.2
Akay, M.T.3
-
6
-
-
4644237392
-
Hypericin as a potential phototherapeutic agent in superficial transitional cell carcinoma of the bladder
-
Kamuhabwa A., Agostinis P., Ahmed B., Landuyt W., van Cleynenbreugel B., van Poppel H., de Witte P. Hypericin as a potential phototherapeutic agent in superficial transitional cell carcinoma of the bladder. Photochem. Photobiol. Sci. 2004, 3:772-780.
-
(2004)
Photochem. Photobiol. Sci.
, vol.3
, pp. 772-780
-
-
Kamuhabwa, A.1
Agostinis, P.2
Ahmed, B.3
Landuyt, W.4
van Cleynenbreugel, B.5
van Poppel, H.6
de Witte, P.7
-
7
-
-
84855927363
-
Low dose hypericin-pDT induces complete tumor regression in BALB/c mice bearing CT26 colon carcinoma
-
Sanovic R., Verwanger T., Hartl A., Krammer B. Low dose hypericin-pDT induces complete tumor regression in BALB/c mice bearing CT26 colon carcinoma. Photodiagnosis Photodyn. Ther. 2011, 8:291-296.
-
(2011)
Photodiagnosis Photodyn. Ther.
, vol.8
, pp. 291-296
-
-
Sanovic, R.1
Verwanger, T.2
Hartl, A.3
Krammer, B.4
-
8
-
-
0031778665
-
Hyperforin possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L
-
Erdelmeier C.A. Hyperforin possibly the major non-nitrogenous secondary metabolite of Hypericum perforatum L. Pharmacopsychiatry 1998, 31:2-6.
-
(1998)
Pharmacopsychiatry
, vol.31
, pp. 2-6
-
-
Erdelmeier, C.A.1
-
9
-
-
12344280271
-
Aristoforin a novel stable derivative of hyperforin, is a potent anticancer agent
-
Gartner M., Muller T., Simon J.C., Giannis A., Sleeman J.P. Aristoforin a novel stable derivative of hyperforin, is a potent anticancer agent. Chembiochem 2005, 6:171-177.
-
(2005)
Chembiochem
, vol.6
, pp. 171-177
-
-
Gartner, M.1
Muller, T.2
Simon, J.C.3
Giannis, A.4
Sleeman, J.P.5
-
10
-
-
0037427379
-
Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier
-
Eisenblätter T., Hüwel S., Galla H.J. Characterisation of the brain multidrug resistance protein (BMDP/ABCG2/BCRP) expressed at the blood-brain barrier. Brain Res. 2003, 971:221-231.
-
(2003)
Brain Res.
, vol.971
, pp. 221-231
-
-
Eisenblätter, T.1
Hüwel, S.2
Galla, H.J.3
-
11
-
-
0037501542
-
A crystal structure of human PXR in complex with the St. John's wort compound hyperforin
-
Watkins R.E., Maglich J.M., Moore L.B., Wisely G.B., Noble S.M., Davis-Searles P.R., Lambert M.H., Kliewer S.A., Redinbo M.R. A crystal structure of human PXR in complex with the St. John's wort compound hyperforin. Biochemistry 2003, 42:1430-1438.
-
(2003)
Biochemistry
, vol.42
, pp. 1430-1438
-
-
Watkins, R.E.1
Maglich, J.M.2
Moore, L.B.3
Wisely, G.B.4
Noble, S.M.5
Davis-Searles, P.R.6
Lambert, M.H.7
Kliewer, S.A.8
Redinbo, M.R.9
-
12
-
-
0034917716
-
The human ATP-binding cassette (ABC) transporter superfamily
-
Dean M., Rzhetsky A., Allikmets R. The human ATP-binding cassette (ABC) transporter superfamily. Genome Res. 2001, 11:1156-1166.
-
(2001)
Genome Res.
, vol.11
, pp. 1156-1166
-
-
Dean, M.1
Rzhetsky, A.2
Allikmets, R.3
-
13
-
-
1042304296
-
Quantitative characterization of direct P-glycoprotein inhibition by St John's wort constituents hypericin and hyperforin
-
Wang E.J., Barecki-Roach M., Johnson W.W. Quantitative characterization of direct P-glycoprotein inhibition by St John's wort constituents hypericin and hyperforin. Pharm. Pharmacol. 2004, 56:123-128.
-
(2004)
Pharm. Pharmacol.
, vol.56
, pp. 123-128
-
-
Wang, E.J.1
Barecki-Roach, M.2
Johnson, W.W.3
-
14
-
-
11144355476
-
Induction and inhibition of cytochromes p450 by the St. John's wort constituent hyperforin in human hepatocyte cultures
-
Komoroski B.J., Zhang S., Cai H., Hutzler J.M., Frye R., Tracy T.S., Strom S.C., Lehmann T., Ang C.Y.W., Cui Y.Yan, Venkataramanan R. Induction and inhibition of cytochromes p450 by the St. John's wort constituent hyperforin in human hepatocyte cultures. Drug Metabol. Disp. 2004, 32:512-518.
-
(2004)
Drug Metabol. Disp.
, vol.32
, pp. 512-518
-
-
Komoroski, B.J.1
Zhang, S.2
Cai, H.3
Hutzler, J.M.4
Frye, R.5
Tracy, T.S.6
Strom, S.C.7
Lehmann, T.8
Ang, C.Y.W.9
Cui, Y.10
Venkataramanan, R.11
-
15
-
-
0033917295
-
Inhibition of human cytochrome P450 enzymes by constituents of St. John's wort, an herbal preparation used in the treatment of depression
-
Obach R.S. Inhibition of human cytochrome P450 enzymes by constituents of St. John's wort, an herbal preparation used in the treatment of depression. J. Pharmacol. Exp. Ther. 2000, 294:88-95.
-
(2000)
J. Pharmacol. Exp. Ther.
, vol.294
, pp. 88-95
-
-
Obach, R.S.1
-
16
-
-
1642579693
-
In vitro metabolism of hyperforin in rat liver microsomal systems
-
Cui Y., Ang C.Y., Beger R.D., Heinze T.M., Hu L., Leakey J. In vitro metabolism of hyperforin in rat liver microsomal systems. Drug Metab. Dispos. 2004, 32:28-34.
-
(2004)
Drug Metab. Dispos.
, vol.32
, pp. 28-34
-
-
Cui, Y.1
Ang, C.Y.2
Beger, R.D.3
Heinze, T.M.4
Hu, L.5
Leakey, J.6
-
17
-
-
84904385632
-
Single pre-treatment with hypericin a St. John's wort secondary metabolite, attenuates cisplatin- and mitoxantrone-induced cell death in A2780, A2780cis and HL-60 cells
-
Jendželovská Z., Jendželovský R., Hiľovská L., Kovaľ J., Mikeš J., Fedoročko P. Single pre-treatment with hypericin a St. John's wort secondary metabolite, attenuates cisplatin- and mitoxantrone-induced cell death in A2780, A2780cis and HL-60 cells. Toxicol. In Vitro 2014, 28:1259-1273.
-
(2014)
Toxicol. In Vitro
, vol.28
, pp. 1259-1273
-
-
Jendželovská, Z.1
Jendželovský, R.2
Hiľovská, L.3
Kovaľ, J.4
Mikeš, J.5
Fedoročko, P.6
-
18
-
-
26244444545
-
Cytochrome P450 mRNA expression
-
Haas C.E., Brazeau Ć.D., Cloen Ć.D., Booker B.M., Frerichs Ć.V., Zaranek Ć.C., Frye R.F., Kufel Ć.T. Cytochrome P450 mRNA expression. Eur. J. Clin. Pharmacol. 2005, 61:583-593.
-
(2005)
Eur. J. Clin. Pharmacol.
, vol.61
, pp. 583-593
-
-
Haas, C.E.1
Brazeau Ć, D.2
Cloen Ć, D.3
Booker, B.M.4
Frerichs Ć, V.5
Zaranek Ć, C.6
Frye, R.F.7
Kufel Ć, T.8
-
21
-
-
84962701136
-
Drug-induced photosensitivity
-
Zhang A.Y., Elmets C.A. Drug-induced photosensitivity. Medscape 2014, 16:325-332.
-
(2014)
Medscape
, vol.16
, pp. 325-332
-
-
Zhang, A.Y.1
Elmets, C.A.2
-
22
-
-
74049162078
-
Drug efflux transporters MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells
-
Jendzelovsky R., Mikes J., Koval J., Soucek K., Prochazkova J., Kello M., Sackova V., Hofmanova J., Kozubik A., Fedorocko P. Drug efflux transporters MRP1 and BCRP, affect the outcome of hypericin-mediated photodynamic therapy in HT-29 adenocarcinoma cells. Photochem. Photobiol. Sci. 2009, 8:1716-1723.
-
(2009)
Photochem. Photobiol. Sci.
, vol.8
, pp. 1716-1723
-
-
Jendzelovsky, R.1
Mikes, J.2
Koval, J.3
Soucek, K.4
Prochazkova, J.5
Kello, M.6
Sackova, V.7
Hofmanova, J.8
Kozubik, A.9
Fedorocko, P.10
-
23
-
-
34247122660
-
Hypericin lights up the way for the potential treatment of nasopharyngeal cancer by photodynamic therapy
-
Olivo M., Du H.Y., Bay B.H. Hypericin lights up the way for the potential treatment of nasopharyngeal cancer by photodynamic therapy. Curr. Clin. Pharmacol. 2006, 1:217-222.
-
(2006)
Curr. Clin. Pharmacol.
, vol.1
, pp. 217-222
-
-
Olivo, M.1
Du, H.Y.2
Bay, B.H.3
-
24
-
-
0036090988
-
Aqueous ethanolic extract of St. John's wort (Hypericum perforatum L.) induces growth inhibition and apoptosis in human malignant cells in vitro
-
Hostanska K., Reichling J., Bommer S., Weber M., Saller R. Aqueous ethanolic extract of St. John's wort (Hypericum perforatum L.) induces growth inhibition and apoptosis in human malignant cells in vitro. Pharmazie 2002, 57:323-331.
-
(2002)
Pharmazie
, vol.57
, pp. 323-331
-
-
Hostanska, K.1
Reichling, J.2
Bommer, S.3
Weber, M.4
Saller, R.5
-
25
-
-
84861588982
-
In vivo photoprotective and anti-inflammatory effect of hyperforin is associated with high antioxidant activity in vitro and ex vivo
-
Meinke M.C., Schanzer S., Haag S.F., Casetti F., Müller M.L., Wölfle U., Kleemann A., Lademann J., Schempp C.M. In vivo photoprotective and anti-inflammatory effect of hyperforin is associated with high antioxidant activity in vitro and ex vivo. Eur. J. Pharm. Biopharm. 2012, 81:346-350.
-
(2012)
Eur. J. Pharm. Biopharm.
, vol.81
, pp. 346-350
-
-
Meinke, M.C.1
Schanzer, S.2
Haag, S.F.3
Casetti, F.4
Müller, M.L.5
Wölfle, U.6
Kleemann, A.7
Lademann, J.8
Schempp, C.M.9
-
26
-
-
84923313188
-
DNA-protective activities of hyperforin and aristoforin
-
Ševčovičová A., Šemeláková M., Plšíková J., Loderer D., Imreová P., Gálová E., Kožurková M., Miadoková E., Fedoročko P. DNA-protective activities of hyperforin and aristoforin. Toxicol. In Vitro 2015, 29:631-637.
-
(2015)
Toxicol. In Vitro
, vol.29
, pp. 631-637
-
-
Ševčovičová, A.1
Šemeláková, M.2
Plšíková, J.3
Loderer, D.4
Imreová, P.5
Gálová, E.6
Kožurková, M.7
Miadoková, E.8
Fedoročko, P.9
-
27
-
-
84858439862
-
Insights into the regulation of protein abundance from proteomic and transcriptomic analyses
-
Vogel Ch., Marcotte E.M. Insights into the regulation of protein abundance from proteomic and transcriptomic analyses. Nat. Rev. Genet. 2013, 13:227-232.
-
(2013)
Nat. Rev. Genet.
, vol.13
, pp. 227-232
-
-
Vogel, C.1
Marcotte, E.M.2
-
28
-
-
84859487429
-
Gene Expression Atlas update - a value added database of microarray and sequencing-based functional genomics experiments
-
Kapushesky M. Gene Expression Atlas update - a value added database of microarray and sequencing-based functional genomics experiments. Nucleic Acids Res. 2012, 40:1077-1081.
-
(2012)
Nucleic Acids Res.
, vol.40
, pp. 1077-1081
-
-
Kapushesky, M.1
-
29
-
-
13644254794
-
Molecular mechanisms of drug resistance
-
Longley D.B., Johnston P.G. Molecular mechanisms of drug resistance. J. Pathol. 2005, 205:275-292.
-
(2005)
J. Pathol.
, vol.205
, pp. 275-292
-
-
Longley, D.B.1
Johnston, P.G.2
-
30
-
-
0037453894
-
Multidrug resistance: can new drugs help chemotherapy score against cancer?
-
Goldman B. Multidrug resistance: can new drugs help chemotherapy score against cancer?. J. Natl. Cancer. Inst. 2003, 95:255-257.
-
(2003)
J. Natl. Cancer. Inst.
, vol.95
, pp. 255-257
-
-
Goldman, B.1
-
31
-
-
0033609355
-
Multidrug-resistant phenotype influences the differentiation of a human colon carcinoma cell line
-
Rimet O., Mirrione A., Barra Y. Multidrug-resistant phenotype influences the differentiation of a human colon carcinoma cell line. Biochem. Biophys. Res. Commun. 1999, 259:43-49.
-
(1999)
Biochem. Biophys. Res. Commun.
, vol.259
, pp. 43-49
-
-
Rimet, O.1
Mirrione, A.2
Barra, Y.3
-
32
-
-
34250795145
-
Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines
-
Gómez-Martínez A., García-Morales P., Carrato Alfredo, Castro-Galache M.D., Soto J.L., Carrasco-García E., García-Bautista M., Guaraz P., Ferragut J.A., Saceda M. Post-transcriptional regulation of P-glycoprotein expression in cancer cell lines. Mol. Cancer Res. 2007, 5:641-653.
-
(2007)
Mol. Cancer Res.
, vol.5
, pp. 641-653
-
-
Gómez-Martínez, A.1
García-Morales, P.2
Carrato, A.3
Castro-Galache, M.D.4
Soto, J.L.5
Carrasco-García, E.6
García-Bautista, M.7
Guaraz, P.8
Ferragut, J.A.9
Saceda, M.10
-
33
-
-
23044472581
-
Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract
-
Gutmann H., Hruz P., Zimmermann C., Beglinger C., Drewe J. Distribution of breast cancer resistance protein (BCRP/ABCG2) mRNA expression along the human GI tract. Biochem. Pharmacol. 2005, 70:695-699.
-
(2005)
Biochem. Pharmacol.
, vol.70
, pp. 695-699
-
-
Gutmann, H.1
Hruz, P.2
Zimmermann, C.3
Beglinger, C.4
Drewe, J.5
-
34
-
-
20144389498
-
-
Xie R., Tan L.H., Polasek E.C., Hong C., Teillol-Foo M., Gordi T., Sharma A., Nickens D.J., Arakawa T., Knuth D.W., Antal E.J. J. Clin. Pharmacol. 2005, 45:352-356.
-
(2005)
J. Clin. Pharmacol.
, vol.45
, pp. 352-356
-
-
Xie, R.1
Tan, L.H.2
Polasek, E.C.3
Hong, C.4
Teillol-Foo, M.5
Gordi, T.6
Sharma, A.7
Nickens, D.J.8
Arakawa, T.9
Knuth, D.W.10
Antal, E.J.11
-
35
-
-
55249095031
-
Cytochrome P450-activated prodrugs: targeted drug delivery
-
Huttunen K.M., Mahonen N., Raunio H., Rautio J. Cytochrome P450-activated prodrugs: targeted drug delivery. Curr. Med. Chem. 2008, 15:2346-2365.
-
(2008)
Curr. Med. Chem.
, vol.15
, pp. 2346-2365
-
-
Huttunen, K.M.1
Mahonen, N.2
Raunio, H.3
Rautio, J.4
-
36
-
-
2442679411
-
Expression of cytochrome P450 in tumor tissues and its association with cancer development
-
Oyama T., Kagawa N., Kunugita N., Kitagawa K., Ogawa M., Yamaguchi T., Suzuki R., Kinaga T., Yashima Y., Ozaki S., Isse T., Kim Y.D., Kim H., Kawamoto T. Expression of cytochrome P450 in tumor tissues and its association with cancer development. Front. Biosci. 2004, 9:1967-1976.
-
(2004)
Front. Biosci.
, vol.9
, pp. 1967-1976
-
-
Oyama, T.1
Kagawa, N.2
Kunugita, N.3
Kitagawa, K.4
Ogawa, M.5
Yamaguchi, T.6
Suzuki, R.7
Kinaga, T.8
Yashima, Y.9
Ozaki, S.10
Isse, T.11
Kim, Y.D.12
Kim, H.13
Kawamoto, T.14
-
37
-
-
4444223732
-
Cytochrome P450 enzymes: novel options for cancer therapeutics
-
McFadyen M.C., Melvin W.T., Murray G.I. Cytochrome P450 enzymes: novel options for cancer therapeutics. Mol. Cancer Ther. 2004, 3:363-371.
-
(2004)
Mol. Cancer Ther.
, vol.3
, pp. 363-371
-
-
McFadyen, M.C.1
Melvin, W.T.2
Murray, G.I.3
-
38
-
-
23344450788
-
Induction of phase I, II and III drug metabolism/transport by xenobiotics
-
Xu C., Li C.Y., Kong A.N. Induction of phase I, II and III drug metabolism/transport by xenobiotics. Arch. Pharm. Res. 2005, 28:249-268.
-
(2005)
Arch. Pharm. Res.
, vol.28
, pp. 249-268
-
-
Xu, C.1
Li, C.Y.2
Kong, A.N.3
-
39
-
-
79959868909
-
Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells
-
Basseville A., Preisser L., de Carné Trécesson S., Boisdron-Celle M., Gamelin E., Coqueret O., Morel A. Irinotecan induces steroid and xenobiotic receptor (SXR) signaling to detoxification pathway in colon cancer cells. Mol. Cancer 2011, 10:80-92.
-
(2011)
Mol. Cancer
, vol.10
, pp. 80-92
-
-
Basseville, A.1
Preisser, L.2
De Carné Trécesson, S.3
Boisdron-Celle, M.4
Gamelin, E.5
Coqueret, O.6
Morel, A.7
-
40
-
-
36148958996
-
Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas
-
Rodriguez-Antona C., Leskela S., Zajac M., Cuadros M., Alves J., Moneo M.V., Martín C., Cigudosa J.C., Carnero A., Robledo M., Benitez J., Martinez-Delgado B. Expression of CYP3A4 as a predictor of response to chemotherapy in peripheral T-cell lymphomas. Blood 2007, 110:3345-3351.
-
(2007)
Blood
, vol.110
, pp. 3345-3351
-
-
Rodriguez-Antona, C.1
Leskela, S.2
Zajac, M.3
Cuadros, M.4
Alves, J.5
Moneo, M.V.6
Martín, C.7
Cigudosa, J.C.8
Carnero, A.9
Robledo, M.10
Benitez, J.11
Martinez-Delgado, B.12
-
41
-
-
0036176510
-
Mechanisms of cancer drug resistance
-
Gottesman M.M. Mechanisms of cancer drug resistance. Annu. Rev. Med. 2002, 53:615-627.
-
(2002)
Annu. Rev. Med.
, vol.53
, pp. 615-627
-
-
Gottesman, M.M.1
|