-
1
-
-
84861116448
-
Tumor microenvironment complexity: emerging roles in cancer therapy
-
Swartz MA, Iida N, Roberts EW, et al. Tumor microenvironment complexity: emerging roles in cancer therapy. Cancer Res 2012;72:2473-80.
-
(2012)
Cancer Res
, vol.72
, pp. 2473-2480
-
-
Swartz, M.A.1
Iida, N.2
Roberts, E.W.3
-
2
-
-
0021867338
-
Cancer as a dynamic developmental disorder
-
Rubin H. Cancer as a dynamic developmental disorder. Cancer Res 1985;45:2935-42.
-
(1985)
Cancer Res
, vol.45
, pp. 2935-2942
-
-
Rubin, H.1
-
3
-
-
0035902141
-
The microenvironment of the tumour-host interface
-
Liotta LA, Kohn EC. The microenvironment of the tumour-host interface. Nature 2001;411:375-9.
-
(2001)
Nature
, vol.411
, pp. 375-379
-
-
Liotta, L.A.1
Kohn, E.C.2
-
4
-
-
33748967069
-
Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer
-
Nelson CM, Bissell MJ. Of extracellular matrix, scaffolds, and signaling: tissue architecture regulates development, homeostasis, and cancer. Annu Rev Cell Dev Biol 2006;22:287-309.
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 287-309
-
-
Nelson, C.M.1
Bissell, M.J.2
-
5
-
-
84987992717
-
Unveiling the role of tumor reactive stroma in cholangiocarcinoma: an opportunity for new therapeutic strategies
-
Cadamuro M, Morton SD, Strazzabosco M, et al. Unveiling the role of tumor reactive stroma in cholangiocarcinoma: an opportunity for new therapeutic strategies. Transl Gastrointest Cancer 2013;2:130-44.
-
(2013)
Transl Gastrointest Cancer
, vol.2
, pp. 130-144
-
-
Cadamuro, M.1
Morton, S.D.2
Strazzabosco, M.3
-
6
-
-
84871821241
-
Stimulus-responsive nanopreparations for tumor targeting
-
Zhu L, Torchilin VP. Stimulus-responsive nanopreparations for tumor targeting. Integr Biol (Camb) 2013;5:96-107.
-
(2013)
Integr Biol (Camb)
, vol.5
, pp. 96-107
-
-
Zhu, L.1
Torchilin, V.P.2
-
7
-
-
84875272580
-
Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery
-
Cheng R, Meng F, Deng C, et al. Dual and multi-stimuli responsive polymeric nanoparticles for programmed site-specific drug delivery. Biomaterials 2013;34:3647-57.
-
(2013)
Biomaterials
, vol.34
, pp. 3647-3657
-
-
Cheng, R.1
Meng, F.2
Deng, C.3
-
8
-
-
14644439267
-
Cancer nanotechnology: opportunities and challenges
-
Ferrari M. Cancer nanotechnology: opportunities and challenges. Nat Rev Cancer 2005;5:161-71.
-
(2005)
Nat Rev Cancer
, vol.5
, pp. 161-171
-
-
Ferrari, M.1
-
9
-
-
40949127319
-
Therapeutic nanoparticles for drug delivery in cancer
-
Cho K, Wang X, Nie S, et al. Therapeutic nanoparticles for drug delivery in cancer. Clin Cancer Res 2008;14:1310-6.
-
(2008)
Clin Cancer Res
, vol.14
, pp. 1310-1316
-
-
Cho, K.1
Wang, X.2
Nie, S.3
-
10
-
-
84865264928
-
Combinatorial nanoparticles for cancer diagnosis and therapy
-
Mukerjee A, Ranjan AP, Vishwanatha JK. Combinatorial nanoparticles for cancer diagnosis and therapy. Curr Med Chem 2012;19:3714-21.
-
(2012)
Curr Med Chem
, vol.19
, pp. 3714-3721
-
-
Mukerjee, A.1
Ranjan, A.P.2
Vishwanatha, J.K.3
-
11
-
-
79952284127
-
Hallmarks of cancer: the next generation
-
Hanahan D, Weinberg RA. Hallmarks of cancer: the next generation. Cell 2011;144:646-74.
-
(2011)
Cell
, vol.144
, pp. 646-674
-
-
Hanahan, D.1
Weinberg, R.A.2
-
12
-
-
0034614637
-
The hallmarks of cancer
-
Hanahan D, Weinberg RA. The hallmarks of cancer. Cell 2000;100:57-70.
-
(2000)
Cell
, vol.100
, pp. 57-70
-
-
Hanahan, D.1
Weinberg, R.A.2
-
13
-
-
77956903803
-
Tumor-host interactions: a far-reaching relationship
-
McAllister SS, Weinberg RA. Tumor-host interactions: a far-reaching relationship. J Clin Oncol 2010;28:4022-8.
-
(2010)
J Clin Oncol
, vol.28
, pp. 4022-4028
-
-
McAllister, S.S.1
Weinberg, R.A.2
-
15
-
-
12344312042
-
Cellular abnormalities of blood vessels as targets in cancer
-
Baluk P, Hashizume H, McDonald DM. Cellular abnormalities of blood vessels as targets in cancer. Curr Opin Genet Dev 2005;15:102-11.
-
(2005)
Curr Opin Genet Dev
, vol.15
, pp. 102-111
-
-
Baluk, P.1
Hashizume, H.2
McDonald, D.M.3
-
16
-
-
0034648765
-
Angiogenesis in cancer and other diseases
-
Carmeliet P, Jain RK. Angiogenesis in cancer and other diseases. Nature 2000;407:249-57.
-
(2000)
Nature
, vol.407
, pp. 249-257
-
-
Carmeliet, P.1
Jain, R.K.2
-
17
-
-
0023219734
-
Transport of molecules in the tumor interstitium: a review
-
Jain RK. Transport of molecules in the tumor interstitium: a review. Cancer Res 1987;47:3039-51.
-
(1987)
Cancer Res
, vol.47
, pp. 3039-3051
-
-
Jain, R.K.1
-
18
-
-
55849099605
-
Active targeting schemes for nanoparticle systems in cancer therapeutics
-
Byrne JD, Betancourt T, Brannon-Peppas L. Active targeting schemes for nanoparticle systems in cancer therapeutics. Adv Drug Deliv Rev 2008;60:1615-26.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 1615-1626
-
-
Byrne, J.D.1
Betancourt, T.2
Brannon-Peppas, L.3
-
19
-
-
77953457158
-
Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting
-
Greish K. Enhanced permeability and retention (EPR) effect for anticancer nanomedicine drug targeting. Methods Mol Biol 2010;624:25-37.
-
(2010)
Methods Mol Biol
, vol.624
, pp. 25-37
-
-
Greish, K.1
-
20
-
-
77951690744
-
Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic
-
Puri A, Loomis K, Smith B, et al. Lipid-based nanoparticles as pharmaceutical drug carriers: from concepts to clinic. Crit Rev Ther Drug Carrier Syst 2009;26:523-80.
-
(2009)
Crit Rev Ther Drug Carrier Syst
, vol.26
, pp. 523-580
-
-
Puri, A.1
Loomis, K.2
Smith, B.3
-
21
-
-
0029551759
-
Microvascular corrosion casting in the study of tumor vascularity: a review
-
discussion 1243-4.
-
Konerding MA, Miodonski AJ, Lametschwandtner A. Microvascular corrosion casting in the study of tumor vascularity: a review. Scanning Microsc 1995;9:1233-43; discussion 1243-4.
-
(1995)
Scanning Microsc
, vol.9
, pp. 1233-1243
-
-
Konerding, M.A.1
Miodonski, A.J.2
Lametschwandtner, A.3
-
22
-
-
0038376001
-
Imaging of angiogenesis: from microscope to clinic
-
McDonald DM, Choyke PL. Imaging of angiogenesis: from microscope to clinic. Nat Med 2003;9:713-25.
-
(2003)
Nat Med
, vol.9
, pp. 713-725
-
-
McDonald, D.M.1
Choyke, P.L.2
-
23
-
-
0036359548
-
Hypoxia-a key regulatory factor in tumour growth
-
Harris AL. Hypoxia-a key regulatory factor in tumour growth. Nat Rev Cancer 2002;2:38-47.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 38-47
-
-
Harris, A.L.1
-
24
-
-
66249108601
-
Understanding the Warburg effect: the metabolic requirements of cell proliferation
-
Vander Heiden MG, Cantley LC, Thompson CB. Understanding the Warburg effect: the metabolic requirements of cell proliferation. Science 2009;324:1029-33.
-
(2009)
Science
, vol.324
, pp. 1029-1033
-
-
Vander Heiden, M.G.1
Cantley, L.C.2
Thompson, C.B.3
-
25
-
-
77955552155
-
Can inhibition of angiogenesis and stimulation of immune response be combined into a more effective antitumor therapy?
-
Szala S, Mitrus I, Sochanik A. Can inhibition of angiogenesis and stimulation of immune response be combined into a more effective antitumor therapy? Cancer Immunol Immunother 2010;59:1449-55.
-
(2010)
Cancer Immunol Immunother
, vol.59
, pp. 1449-1455
-
-
Szala, S.1
Mitrus, I.2
Sochanik, A.3
-
26
-
-
0019202568
-
pH-sensitive liposomes: possible clinical implications
-
Yatvin MB, Kreutz W, Horwitz BA, et al. pH-sensitive liposomes: possible clinical implications. Science 1980;210:1253-5.
-
(1980)
Science
, vol.210
, pp. 1253-1255
-
-
Yatvin, M.B.1
Kreutz, W.2
Horwitz, B.A.3
-
27
-
-
77954735171
-
A novel nanoparticulate formulation of arsenic trioxide with enhanced therapeutic efficacy in a murine model of breast cancer
-
Ahn RW, Chen F, Chen H, et al. A novel nanoparticulate formulation of arsenic trioxide with enhanced therapeutic efficacy in a murine model of breast cancer. Clin Cancer Res 2010;16:3607-17.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 3607-3617
-
-
Ahn, R.W.1
Chen, F.2
Chen, H.3
-
28
-
-
80052575055
-
Rapid dissolution of ZnO nanocrystals in acidic cancer microenvironment leading to preferential apoptosis
-
Sasidharan A, Chandran P, Menon D, et al. Rapid dissolution of ZnO nanocrystals in acidic cancer microenvironment leading to preferential apoptosis. Nanoscale 2011;3:3657-69.
-
(2011)
Nanoscale
, vol.3
, pp. 3657-3669
-
-
Sasidharan, A.1
Chandran, P.2
Menon, D.3
-
29
-
-
77955175216
-
Strategies in the design of nanoparticles for therapeutic applications
-
Petros RA, DeSimone JM. Strategies in the design of nanoparticles for therapeutic applications. Nat Rev Drug Discov 2010;9:615-27.
-
(2010)
Nat Rev Drug Discov
, vol.9
, pp. 615-627
-
-
Petros, R.A.1
DeSimone, J.M.2
-
30
-
-
78650077255
-
Polymer-caged nanobins for synergistic cisplatin-doxorubicin combination chemotherapy
-
Lee SM, O'Halloran TV, Nguyen ST. Polymer-caged nanobins for synergistic cisplatin-doxorubicin combination chemotherapy. J Am Chem Soc 2010;132:17130-8.
-
(2010)
J Am Chem Soc
, vol.132
, pp. 17130-17138
-
-
Lee, S.M.1
O'Halloran, T.V.2
Nguyen, S.T.3
-
31
-
-
84885104211
-
"pH phoresis": A new concept that can be used for improving drug delivery to tumor cells
-
Won YY, Lee H. "pH phoresis": A new concept that can be used for improving drug delivery to tumor cells. J Control Release 2013;170:396-400.
-
(2013)
J Control Release
, vol.170
, pp. 396-400
-
-
Won, Y.Y.1
Lee, H.2
-
32
-
-
84865065431
-
Maximum-tolerated dose, optimum biologic dose, or optimum clinical value: dosing determination of cancer therapies
-
Marshall JL. Maximum-tolerated dose, optimum biologic dose, or optimum clinical value: dosing determination of cancer therapies. J Clin Oncol 2012;30:2815-6.
-
(2012)
J Clin Oncol
, vol.30
, pp. 2815-2816
-
-
Marshall, J.L.1
-
33
-
-
0034032882
-
Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer
-
Browder T, Butterfield CE, Kräling BM, et al. Antiangiogenic scheduling of chemotherapy improves efficacy against experimental drug-resistant cancer. Cancer Res 2000;60:1878-86.
-
(2000)
Cancer Res
, vol.60
, pp. 1878-1886
-
-
Browder, T.1
Butterfield, C.E.2
Kräling, B.M.3
-
34
-
-
0034087691
-
Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regressionwithout overt toxicity
-
Klement G, Baruchel S, Rak J, et al. Continuous low-dose therapy with vinblastine and VEGF receptor-2 antibody induces sustained tumor regressionwithout overt toxicity. J Clin Invest 2000;105:R15-24.
-
(2000)
J Clin Invest
, vol.105
, pp. R15-R24
-
-
Klement, G.1
Baruchel, S.2
Rak, J.3
-
35
-
-
0034048358
-
Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice
-
Hanahan D, Bergers G, Bergsland E. Less is more, regularly: metronomic dosing of cytotoxic drugs can target tumor angiogenesis in mice. J Clin Invest 2000;105:1045-7.
-
(2000)
J Clin Invest
, vol.105
, pp. 1045-1047
-
-
Hanahan, D.1
Bergers, G.2
Bergsland, E.3
-
36
-
-
14644446018
-
A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer
-
Pietras K, Hanahan D. A multitargeted, metronomic, and maximum-tolerated dose "chemo-switch" regimen is antiangiogenic, producing objective responses and survival benefit in a mouse model of cancer. J Clin Oncol 2005;23:939-52.
-
(2005)
J Clin Oncol
, vol.23
, pp. 939-952
-
-
Pietras, K.1
Hanahan, D.2
-
37
-
-
0035214416
-
Metronomic scheduling: the future of chemotherapy?
-
Gasparini G. Metronomic scheduling: the future of chemotherapy? Lancet Oncol 2001;2:733-40.
-
(2001)
Lancet Oncol
, vol.2
, pp. 733-740
-
-
Gasparini, G.1
-
38
-
-
31544471152
-
The effect of Topotecan on oxidative stress in MCF-7 human breast cancer cell line
-
Timur M, Akbas SH, Ozben T. The effect of Topotecan on oxidative stress in MCF-7 human breast cancer cell line. Acta Biochim Pol 2005;52:897-902.
-
(2005)
Acta Biochim Pol
, vol.52
, pp. 897-902
-
-
Timur, M.1
Akbas, S.H.2
Ozben, T.3
-
39
-
-
80052356005
-
Enhanced antitumor activity of low-dose continuous administration schedules of topotecan in prostate cancer
-
Aljuffali IA, Mock JN, Costyn LJ, et al. Enhanced antitumor activity of low-dose continuous administration schedules of topotecan in prostate cancer. Cancer Biol Ther 2011;12:407-20.
-
(2011)
Cancer Biol Ther
, vol.12
, pp. 407-420
-
-
Aljuffali, I.A.1
Mock, J.N.2
Costyn, L.J.3
-
40
-
-
33746698886
-
BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer
-
Nagashima S, Soda H, Oka M, et al. BCRP/ABCG2 levels account for the resistance to topoisomerase I inhibitors and reversal effects by gefitinib in non-small cell lung cancer. Cancer Chemother Pharmacol 2006;58:594-600.
-
(2006)
Cancer Chemother Pharmacol
, vol.58
, pp. 594-600
-
-
Nagashima, S.1
Soda, H.2
Oka, M.3
-
41
-
-
34447503912
-
Antiproliferation in human EA.hy926 endothelial cells and inhibition of VEGF expression in PC-3 cells by topotecan
-
Yang X, Zhang C, Ying M, et al. Antiproliferation in human EA.hy926 endothelial cells and inhibition of VEGF expression in PC-3 cells by topotecan. Pharmazie 2007;62:534-8.
-
(2007)
Pharmazie
, vol.62
, pp. 534-538
-
-
Yang, X.1
Zhang, C.2
Ying, M.3
-
42
-
-
33644860585
-
Topotecan is a substrate for multidrug resistance associated protein 4
-
Tian Q, Zhang J, Chan SY, et al. Topotecan is a substrate for multidrug resistance associated protein 4. Curr Drug Metab 2006;7:105-18.
-
(2006)
Curr Drug Metab
, vol.7
, pp. 105-118
-
-
Tian, Q.1
Zhang, J.2
Chan, S.Y.3
-
43
-
-
70349135129
-
Anti-angiogenic properties of metronomic topotecan in ovarian carcinoma
-
Merritt WM, Danes CG, Shahzad MM, et al. Anti-angiogenic properties of metronomic topotecan in ovarian carcinoma. Cancer Biol Ther 2009;8:1596-603.
-
(2009)
Cancer Biol Ther
, vol.8
, pp. 1596-1603
-
-
Merritt, W.M.1
Danes, C.G.2
Shahzad, M.M.3
-
44
-
-
3042685415
-
Drug delivery systems: past, present, and future
-
Mainardes RM, Silva LP. Drug delivery systems: past, present, and future. Curr Drug Targets 2004;5:449-55.
-
(2004)
Curr Drug Targets
, vol.5
, pp. 449-455
-
-
Mainardes, R.M.1
Silva, L.P.2
-
46
-
-
0042173127
-
A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-bindingdoxorubicin prodrug that is cleaved by matrix metalloproteinase 2
-
Mansour AM, Drevs J, Esser N, et al. A new approach for the treatment of malignant melanoma: enhanced antitumor efficacy of an albumin-bindingdoxorubicin prodrug that is cleaved by matrix metalloproteinase 2. Cancer Res 2003;63:4062-6.
-
(2003)
Cancer Res
, vol.63
, pp. 4062-4066
-
-
Mansour, A.M.1
Drevs, J.2
Esser, N.3
-
47
-
-
0038518258
-
Chemical approaches to triggerable lipid vesicles for drug and gene delivery
-
Guo X, Szoka FC Jr. Chemical approaches to triggerable lipid vesicles for drug and gene delivery. Acc Chem Res 2003;36:335-41.
-
(2003)
Acc Chem Res
, vol.36
, pp. 335-341
-
-
Guo, X.1
Szoka, F.C.2
-
48
-
-
79952165883
-
Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo
-
Dhar S, Kolishetti N, Lippard SJ, et al. Targeted delivery of a cisplatin prodrug for safer and more effective prostate cancer therapy in vivo. Proc Natl Acad Sci U S A 2011;108:1850-5.
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 1850-1855
-
-
Dhar, S.1
Kolishetti, N.2
Lippard, S.J.3
-
49
-
-
0030738677
-
Multidrug resistance: molecular mechanisms and clinical relevance
-
Ling V. Multidrug resistance: molecular mechanisms and clinical relevance. Cancer Chemother Pharmacol 1997;40 Suppl:S3-8.
-
(1997)
Cancer Chemother Pharmacol
, vol.40
, pp. S3-S8
-
-
Ling, V.1
-
50
-
-
8144228952
-
Friends or foes - bipolar effects of the tumour stroma in cancer
-
Mueller MM, Fusenig NE. Friends or foes - bipolar effects of the tumour stroma in cancer. Nat Rev Cancer 2004;4:839-49.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 839-849
-
-
Mueller, M.M.1
Fusenig, N.E.2
-
52
-
-
34447276000
-
Tumor microenvironment: the role of the tumor stroma in cancer
-
Li H, Fan X, Houghton J. Tumor microenvironment: the role of the tumor stroma in cancer. J Cell Biochem 2007;101:805-15.
-
(2007)
J Cell Biochem
, vol.101
, pp. 805-815
-
-
Li, H.1
Fan, X.2
Houghton, J.3
-
53
-
-
33645088428
-
Metastasis: cell-autonomous mechanisms versus contributions by the tumor microenvironment
-
Kopfstein L, Christofori G. Metastasis: cell-autonomous mechanisms versus contributions by the tumor microenvironment. Cell Mol Life Sci 2006;63:449-68.
-
(2006)
Cell Mol Life Sci
, vol.63
, pp. 449-468
-
-
Kopfstein, L.1
Christofori, G.2
-
54
-
-
34848863979
-
Impact of the non-cellular tumor microenvironment on metastasis: potential therapeutic and imagingopportunities
-
Cretu A, Brooks PC. Impact of the non-cellular tumor microenvironment on metastasis: potential therapeutic and imagingopportunities. J Cell Physiol 2007;213:391-402.
-
(2007)
J Cell Physiol
, vol.213
, pp. 391-402
-
-
Cretu, A.1
Brooks, P.C.2
-
55
-
-
35148881028
-
Drug resistance and the solid tumor microenvironment
-
Trédan O, Galmarini CM, Patel K, et al. Drug resistance and the solid tumor microenvironment. J Natl Cancer Inst 2007;99:1441-54.
-
(2007)
J Natl Cancer Inst
, vol.99
, pp. 1441-1454
-
-
Trédan, O.1
Galmarini, C.M.2
Patel, K.3
-
57
-
-
4944266313
-
High interstitial fluid pressure - an obstacle in cancer therapy
-
Heldin CH, Rubin K, Pietras K, et al. High interstitial fluid pressure - an obstacle in cancer therapy. Nat Rev Cancer 2004;4:806-13.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 806-813
-
-
Heldin, C.H.1
Rubin, K.2
Pietras, K.3
-
58
-
-
33847356987
-
Drug distribution in tumors: mechanisms, role in drug resistance, and methods for modification
-
Di Paolo A, Bocci G. Drug distribution in tumors: mechanisms, role in drug resistance, and methods for modification. Curr Oncol Rep 2007;9:109-14.
-
(2007)
Curr Oncol Rep
, vol.9
, pp. 109-114
-
-
Di Paolo, A.1
Bocci, G.2
-
59
-
-
82855168354
-
Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics
-
Upreti M, Jamshidi-Parsian A, Koonce NA, et al. Tumor-Endothelial Cell Three-dimensional Spheroids: New Aspects to Enhance Radiation and Drug Therapeutics. Transl Oncol 2011;4:365-76.
-
(2011)
Transl Oncol
, vol.4
, pp. 365-376
-
-
Upreti, M.1
Jamshidi-Parsian, A.2
Koonce, N.A.3
-
60
-
-
0015312069
-
Effects of intercellular contact on repair of radiation damage
-
Durand RE, Sutherland RM. Effects of intercellular contact on repair of radiation damage. Exp Cell Res 1972;71:75-80.
-
(1972)
Exp Cell Res
, vol.71
, pp. 75-80
-
-
Durand, R.E.1
Sutherland, R.M.2
-
62
-
-
33646568511
-
Mechanisms and strategies to overcome multiple drug resistance in cancer
-
Ozben T. Mechanisms and strategies to overcome multiple drug resistance in cancer. FEBS Lett 2006;580:2903-9.
-
(2006)
FEBS Lett
, vol.580
, pp. 2903-2909
-
-
Ozben, T.1
-
63
-
-
84860697028
-
The tumor microenvironment is a dominant force in multidrug resistance
-
Correia AL, Bissell MJ. The tumor microenvironment is a dominant force in multidrug resistance. Drug Resist Updat 2012;15:39-49.
-
(2012)
Drug Resist Updat
, vol.15
, pp. 39-49
-
-
Correia, A.L.1
Bissell, M.J.2
-
65
-
-
84857197449
-
Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment
-
Akiyama K, Ohga N, Hida Y, et al. Tumor endothelial cells acquire drug resistance by MDR1 up-regulation via VEGF signaling in tumor microenvironment. Am J Pathol 2012;180:1283-93.
-
(2012)
Am J Pathol
, vol.180
, pp. 1283-1293
-
-
Akiyama, K.1
Ohga, N.2
Hida, Y.3
-
66
-
-
36849067019
-
Nanocarriers as an emerging platform for cancer therapy
-
Peer D, Karp JM, Hong S, et al. Nanocarriers as an emerging platform for cancer therapy. Nat Nanotechnol 2007;2:751-60.
-
(2007)
Nat Nanotechnol
, vol.2
, pp. 751-760
-
-
Peer, D.1
Karp, J.M.2
Hong, S.3
-
67
-
-
0034104453
-
Resistance mechanisms associated with altered intracellular distribution of anticancer agents
-
Larsen AK, Escargueil AE, Skladanowski A. Resistance mechanisms associated with altered intracellular distribution of anticancer agents. Pharmacol Ther 2000;85:217-29.
-
(2000)
Pharmacol Ther
, vol.85
, pp. 217-229
-
-
Larsen, A.K.1
Escargueil, A.E.2
Skladanowski, A.3
-
68
-
-
0026608797
-
gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis
-
Schnitzer JE. gp60 is an albumin-binding glycoprotein expressed by continuous endothelium involved in albumin transcytosis. Am J Physiol 1992;262:H246-54.
-
(1992)
Am J Physiol
, vol.262
, pp. H246-H254
-
-
Schnitzer, J.E.1
-
69
-
-
0030798998
-
Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway
-
Tiruppathi C, Song W, Bergenfeldt M, et al. Gp60 activation mediates albumin transcytosis in endothelial cells by tyrosine kinase-dependent pathway. J Biol Chem 1997;272:25968-75.
-
(1997)
J Biol Chem
, vol.272
, pp. 25968-25975
-
-
Tiruppathi, C.1
Song, W.2
Bergenfeldt, M.3
-
70
-
-
0021323613
-
Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture
-
Sage H, Johnson C, Bornstein P. Characterization of a novel serum albumin-binding glycoprotein secreted by endothelial cells in culture. J Biol Chem 1984;259:3993-4007.
-
(1984)
J Biol Chem
, vol.259
, pp. 3993-4007
-
-
Sage, H.1
Johnson, C.2
Bornstein, P.3
-
71
-
-
33749556658
-
Galectin-1: a small protein with major functions
-
Camby I, Le Mercier M, Lefranc F, et al. Galectin-1: a small protein with major functions. Glycobiology 2006;16:137R-157R.
-
(2006)
Glycobiology
, vol.16
, pp. 137R-157R
-
-
Camby, I.1
Le Mercier, M.2
Lefranc, F.3
-
72
-
-
84879601446
-
Radiation-induced galectin-1 by endothelial cells: a promising molecular target for preferential drug delivery to the tumor vasculature
-
Upreti M, Jamshidi-Parsian A, Apana S, et al. Radiation-induced galectin-1 by endothelial cells: a promising molecular target for preferential drug delivery to the tumor vasculature. J Mol Med (Berl) 2013;91:497-506.
-
(2013)
J Mol Med (Berl)
, vol.91
, pp. 497-506
-
-
Upreti, M.1
Jamshidi-Parsian, A.2
Apana, S.3
-
73
-
-
33750474852
-
Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy
-
Thijssen VL, Postel R, Brandwijk RJ, et al. Galectin-1 is essential in tumor angiogenesis and is a target for antiangiogenesis therapy. Proc Natl Acad Sci U S A 2006;103:15975-80.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 15975-15980
-
-
Thijssen, V.L.1
Postel, R.2
Brandwijk, R.J.3
-
74
-
-
33644692007
-
P-glycoprotein recognition of substrates and circumvention through rational drug design
-
Raub TJ. P-glycoprotein recognition of substrates and circumvention through rational drug design. Mol Pharm 2006;3:3-25.
-
(2006)
Mol Pharm
, vol.3
, pp. 3-25
-
-
Raub, T.J.1
-
75
-
-
70350747513
-
Role of nanocarrier systems in cancer nanotherapy
-
Mozafari MR, Pardakhty A, Azarmi S, et al. Role of nanocarrier systems in cancer nanotherapy. J Liposome Res 2009;19:310-21.
-
(2009)
J Liposome Res
, vol.19
, pp. 310-321
-
-
Mozafari, M.R.1
Pardakhty, A.2
Azarmi, S.3
-
76
-
-
28744442266
-
MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle
-
Mulder WJ, Strijkers GJ, Habets JW, et al. MR molecular imaging and fluorescence microscopy for identification of activated tumor endothelium using a bimodal lipidic nanoparticle. FASEB J 2005;19:2008-10.
-
(2005)
FASEB J
, vol.19
, pp. 2008-2010
-
-
Mulder, W.J.1
Strijkers, G.J.2
Habets, J.W.3
-
77
-
-
0031862889
-
Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging
-
Sipkins DA, Cheresh DA, Kazemi MR, et al. Detection of tumor angiogenesis in vivo by alphaVbeta3-targeted magnetic resonance imaging. Nat Med 1998;4:623-6.
-
(1998)
Nat Med
, vol.4
, pp. 623-626
-
-
Sipkins, D.A.1
Cheresh, D.A.2
Kazemi, M.R.3
-
78
-
-
0141731298
-
Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 tesla magnetic resonance imaging
-
Winter PM, Caruthers SD, Kassner A, et al. Molecular imaging of angiogenesis in nascent Vx-2 rabbit tumors using a novel alpha(nu)beta3-targeted nanoparticle and 1.5 tesla magnetic resonance imaging. Cancer Res 2003;63:5838-43.
-
(2003)
Cancer Res
, vol.63
, pp. 5838-5843
-
-
Winter, P.M.1
Caruthers, S.D.2
Kassner, A.3
-
79
-
-
33847693865
-
Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner
-
Zhang C, Jugold M, Woenne EC, et al. Specific targeting of tumor angiogenesis by RGD-conjugated ultrasmall superparamagnetic iron oxide particles using a clinical 1.5-T magnetic resonance scanner. Cancer Res 2007;67:1555-62.
-
(2007)
Cancer Res
, vol.67
, pp. 1555-1562
-
-
Zhang, C.1
Jugold, M.2
Woenne, E.C.3
-
80
-
-
12144287687
-
18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis
-
Chen X, Park R, Shahinian AH, et al. 18F-labeled RGD peptide: initial evaluation for imaging brain tumor angiogenesis. Nucl Med Biol 2004;31:179-89.
-
(2004)
Nucl Med Biol
, vol.31
, pp. 179-189
-
-
Chen, X.1
Park, R.2
Shahinian, A.H.3
-
81
-
-
20344367518
-
Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression
-
Achilefu S, Bloch S, Markiewicz MA, et al. Synergistic effects of light-emitting probes and peptides for targeting and monitoring integrin expression. Proc Natl Acad Sci U S A 2005;102:7976-81.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 7976-7981
-
-
Achilefu, S.1
Bloch, S.2
Markiewicz, M.A.3
-
82
-
-
15744406017
-
Integrin alpha v beta 3-targeted imaging of lung cancer
-
Chen X, Sievers E, Hou Y, et al. Integrin alpha v beta 3-targeted imaging of lung cancer. Neoplasia 2005;7:271-9.
-
(2005)
Neoplasia
, vol.7
, pp. 271-279
-
-
Chen, X.1
Sievers, E.2
Hou, Y.3
-
83
-
-
33750971995
-
In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model
-
Hsu AR, Hou LC, Veeravagu A, et al. In vivo near-infrared fluorescence imaging of integrin alphavbeta3 in an orthotopic glioblastoma model. Mol Imaging Biol 2006;8:315-23.
-
(2006)
Mol Imaging Biol
, vol.8
, pp. 315-323
-
-
Hsu, A.R.1
Hou, L.C.2
Veeravagu, A.3
-
84
-
-
18844380738
-
Probing for integrin alpha v beta3 binding of RGD peptides using fluorescence polarization
-
Wang W, Wu Q, Pasuelo M, et al. Probing for integrin alpha v beta3 binding of RGD peptides using fluorescence polarization. Bioconjug Chem 2005;16:729-34.
-
(2005)
Bioconjug Chem
, vol.16
, pp. 729-734
-
-
Wang, W.1
Wu, Q.2
Pasuelo, M.3
-
85
-
-
33846545130
-
Biomimetic amplification of nanoparticle homing to tumors
-
Simberg D, Duza T, Park JH, et al. Biomimetic amplification of nanoparticle homing to tumors. Proc Natl Acad Sci U S A 2007;104:932-6.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 932-936
-
-
Simberg, D.1
Duza, T.2
Park, J.H.3
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