Polymeric microcontainers improve oral bioavailability of furosemide

International Journal of Pharmaceutics

Volumn 504, Issue 1-2, 2016, Pages 98-109

  Nielsen, Line Hagner ^a   Melero, Ana ^b   Keller, Stephan Sylvest ^a   Jacobsen, Jette ^c   Garrigues, Teresa ^b   Rades, Thomas ^c   Müllertz, Anette ^c   Boisen, Anja ^a  

^a TECHNICAL UNIVERSITY OF DENMARK   (Denmark)

^b UNIVERSITY OF VALENCIA   (Spain)

^c UNIVERSITY OF COPENHAGEN   (Denmark)

Author keywords

Delivery systems; Furosemide; Intestinal perfusion; Micro devices; Oral bioavailability; Oral delivery

Indexed keywords

DRUG CARRIER; EUDRAGIT; FUROSEMIDE; MICROCONTAINER; POLYMER; UNCLASSIFIED DRUG; EPOXIDE; METHYLMETHACRYLATE-METHACRYLIC ACID COPOLYMER; POLYMETHACRYLIC ACID DERIVATIVE; SU-8 COMPOUND;

ABSORPTION RATE CONSTANT; ANIMAL EXPERIMENT; APPARENT PERMEABILITY; ARTICLE; CONTROLLED DRUG RELEASE; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG RELEASE; DRUG RETENTION; DRUG SOLUBILITY; ENTEROHEPATIC CIRCULATION; FEMALE; IN VITRO STUDY; IN VIVO STUDY; INTESTINE ABSORPTION; INTESTINE PERFUSION; MALE; MICROTECHNOLOGY; NONHUMAN; PRIORITY JOURNAL; RAT; TURNOVER TIME; WATER ABSORPTION; ANIMAL; BIOAVAILABILITY; BLOOD; CACO-2 CELL LINE; CHEMISTRY; HUMAN; INTESTINE; METABOLISM; MUCUS; ORAL DRUG ADMINISTRATION; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; BIOLOGICAL AVAILABILITY; CACO-2 CELLS; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; EPOXY COMPOUNDS; FEMALE; FUROSEMIDE; HUMANS; INTESTINES; MUCUS; POLYMERS; POLYMETHACRYLIC ACIDS; RATS, WISTAR;

EID: 84962641334     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2016.03.050     Document Type: Article

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