FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

Nature Communications

Volumn 7, Issue , 2016, Pages

  Slebe, Felipe ^a   Rojo, Federico ^b,c   Vinaixa, Maria ^d,e   García Rocha, Mar ^a   Testoni, Giorgia ^a   Guiu, Marc ^a   Planet, Evarist ^a   Samino, Sara ^d,e   Arenas, Enrique J ^a   Beltran, Antoni ^d,e   Rovira, Ana ^b   Lluch, Ana ^f   Salvatella, Xavier ^a,g   Yanes, Oscar ^d,e   Albanell, Joan ^b,h   Guinovart, Joan J ^a,e,i   Gomis, Roger R ^a,g  

^a INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Spain)

^b HOSPITAL DEL MAR   (Spain)

^c UAM)   (Spain)

^d UNIVERSITAT ROVIRA I VIRGILI   (Spain)

^e INSTITUTO DE SALUD CARLOS III   (Spain)

^f HOSPITAL CLÍNICO UNIVERSITARIO   (Spain)

^g INSTITUCIÓ CATALANA DE RECERCA I ESTUDIS AVANÇATS ICREA   (Spain)

^h UNIVERSITAT POMPEU FABRA   (Spain)

ⁱ UNIVERSITY OF BARCELONA   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

HEPATOCYTE NUCLEAR FACTOR 3ALPHA; HEPATOCYTE NUCLEAR FACTOR 3BETA; LIPID; TRIACYLGLYCEROL LIPASE; 4-METHYLENE-2-OCTYL-5-OXOFURAN-3-CARBOXYLIC ACID; DOXYCYCLINE; ENZYME INHIBITOR; FOXA1 PROTEIN, HUMAN; FOXA2 PROTEIN, HUMAN; GAMMA BUTYROLACTONE; LACTONE; LIPG PROTEIN, HUMAN; SMALL INTERFERING RNA; TETRAHYDROLIPSTATIN;

ADAPTATION; CANCER; CELLS AND CELL COMPONENTS; CYTOGENETICS; ENZYME ACTIVITY; GROWTH RESPONSE; LIPID;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BREAST CANCER; CANCER GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; LIPID METABOLISM; LIPID TRANSPORT; LIPOGENESIS; MOUSE; NONHUMAN; PRECURSOR; PROTEIN EXPRESSION; TRANSFORMED CELL; ANALOGS AND DERIVATIVES; ANIMAL; ANTAGONISTS AND INHIBITORS; BREAST TUMOR; CELL MOTION; DRUG EFFECTS; DRUG SCREENING; FEMALE; GENE EXPRESSION REGULATION; GENETICS; MCF-7 CELL LINE; METABOLISM; NUDE MOUSE; PATHOLOGY; SIGNAL TRANSDUCTION; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE; TUMOR INVASION;

4-BUTYROLACTONE; ANIMALS; BIOLOGICAL TRANSPORT; BREAST NEOPLASMS; CELL LINE, TUMOR; CELL MOVEMENT; CELL PROLIFERATION; DOXYCYCLINE; ENZYME INHIBITORS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HEPATOCYTE NUCLEAR FACTOR 3-ALPHA; HEPATOCYTE NUCLEAR FACTOR 3-BETA; HUMANS; LACTONES; LIPASE; LIPID METABOLISM; MCF-7 CELLS; MICE; MICE, NUDE; NEOPLASM INVASIVENESS; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84962634698     PISSN: None     EISSN: 20411723     Source Type: Journal    
DOI: 10.1038/ncomms11199     Document Type: Article

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