The human cadherin 11 is a pro-apoptotic tumor suppressor modulating cell stemness through Wnt/Β-catenin signaling and silenced in common carcinomas

Oncogene

Volumn 31, Issue 34, 2012, Pages 3901-3912

  Li, L ^a   Ying, J ^a,b   Li, H ^a   Zhang, Y ^a   Shu, X ^a   Fan, Y ^a   Tan, J ^c   Cao, Y ^d   Tsao, S W ^e   Srivastava, G ^e   Chan, A T C ^a   Tao, Q ^a  

^a CHINESE UNIVERSITY OF HONG KONG   (Hong Kong)

^b CANCER HOSPITAL   (China)

^c Johns Hopkins Singapore   (Singapore)

^d CENTRAL SOUTH UNIVERSITY   (China)

^e UNIVERSITY OF HONG KONG   (Hong Kong)

Author keywords

cadherin; carcinoma; CDH11; methylation; tumor suppressor gene

Indexed keywords

BETA CATENIN; CADHERIN; CADHERIN 11; PROTEIN KINASE B; RHO KINASE; UNCLASSIFIED DRUG; WNT PROTEIN;

ARTICLE; CANCER INHIBITION; CARCINOMA; CHROMOSOME 16Q; COMPARATIVE GENOMIC HYBRIDIZATION; CPG ISLAND; DEMETHYLATION; DNA METHYLATION; DOWN REGULATION; EPIGENETICS; EPITHELIAL MESENCHYMAL TRANSITION; GENE DELETION; GENE EXPRESSION; GENE SILENCING; HEMIZYGOSITY; PRIORITY JOURNAL; PROMOTER REGION;

APOPTOSIS; BETA CATENIN; BLOTTING, WESTERN; CADHERINS; CELL LINE; CELL LINE, TUMOR; CELL MEMBRANE; CHROMOSOMES, HUMAN, PAIR 16; COMPARATIVE GENOMIC HYBRIDIZATION; CPG ISLANDS; DNA METHYLATION; EPITHELIAL-MESENCHYMAL TRANSITION; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; HCT116 CELLS; HUMANS; MICROSCOPY, CONFOCAL; NEOPLASMS; NEOPLASTIC STEM CELLS; PROMOTER REGIONS, GENETIC; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS; WNT PROTEINS;

EID: 84865417923     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2011.541     Document Type: Article

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