Inhibition of notch signaling ameliorates acute kidney failure and downregulates platelet-derived growth factor receptor β in the mouse model

Cells Tissues Organs

Volumn 201, Issue 2, 2016, Pages 109-117

  Kramer, Jan ^a,d   Schwanbeck, Ralf ^b   Pagel, Horst ^a   Cakiroglu, Figen ^a   Rohwedel, Jürgen ^a   Just, Ursula ^b,c  

^a UNIVERSITY OF LÜBECK   (Germany)

^b UNIVERSITY OF KIEL   (Germany)

^c MAX PLANCK INSTITUTE FOR HEART AND LUNG RESEARCH   (Germany)

^d Laboratory Dr Kramer and Colleagues   (Germany)

Author keywords

Acute kidney failure; Notch; Platelet derived growth factor receptor

Indexed keywords

CREATININE; DELTA LIKE 1 PROTEIN; DELTA LIKE 4 PROTEIN; GAMMA SECRETASE INHIBITOR; HEY2 PROTEIN; HEYL PROTEIN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; ID1 4 PROTEIN; JAGGED1; JAGGED2 PROTEIN; MEMBRANE PROTEIN; NOTCH RECEPTOR; NOTCH1 RECEPTOR; NOTCH2 RECEPTOR; NOTCH3 RECEPTOR; NOTCH4 RECEPTOR; PLATELET DERIVED GROWTH FACTOR BETA RECEPTOR; PROTEIN; SNAI1 PROTEIN; TRANSCRIPTION FACTOR HES 1; TRANSCRIPTION FACTOR SLUG; TRANSCRIPTION FACTOR SOX9; UNCLASSIFIED DRUG; UREA; ENZYME INHIBITOR; SECRETASE;

ACUTE KIDNEY FAILURE; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CREATININE BLOOD LEVEL; DOWN REGULATION; GENE EXPRESSION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REAL TIME POLYMERASE CHAIN REACTION; REPERFUSION INJURY; SIGNAL TRANSDUCTION; UPREGULATION; UREA BLOOD LEVEL; WESTERN BLOTTING; ACUTE KIDNEY INJURY; ANIMAL; ANTAGONISTS AND INHIBITORS; DISEASE MODEL; DRUG EFFECTS; GENETICS; KIDNEY; METABOLISM; PATHOLOGY;

ACUTE KIDNEY INJURY; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; DISEASE MODELS, ANIMAL; DOWN-REGULATION; ENZYME INHIBITORS; KIDNEY; MALE; MICE; RECEPTOR, PLATELET-DERIVED GROWTH FACTOR BETA; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION;

EID: 84962595740     PISSN: 14226405     EISSN: 14226421     Source Type: Journal    
DOI: 10.1159/000442463     Document Type: Article

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