Notch-3 receptor activation drives inflammation and fibrosis following tubulointerstitial kidney injury

Journal of Pathology

Volumn 228, Issue 3, 2012, Pages 286-299

  Djudjaj, Sonja ^a,b   Chatziantoniou, Christos ^c   Raffetseder, Ute ^b   Guerrot, Dominique ^c   Dussaule, Jean Claude ^c   Boor, Peter ^b,d   Kerroch, Monique ^c   Hanssen, Lydia ^b   Brandt, Sabine ^a   Dittrich, Annemarie ^a   Ostendorf, Tammo ^b   Floege, Jürgen ^b   Zhu, Cheng ^a   Lindenmeyer, Maja ^e   Cohen, Clemens D ^e   Mertens, Peter R ^a  

^a OTTO VON GUERICKE UNIVERSITY   (Germany)

^b RWTH AACHEN UNIVERSITY   (Germany)

^c INSERM   (France)

^d Physics and Informatics   (Slovakia)

^e UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

chemotaxis; fibrosis; inflammation; kidney diseases; Notch receptor; proliferation; tubular cells

Indexed keywords

CHEMOKINE; COLLAGEN; NOTCH RECEPTOR; NOTCH3 RECEPTOR; TRANSFORMING GROWTH FACTOR BETA;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CELL INFILTRATION; CELL LOSS; CELL PROLIFERATION; CHEMOTAXIS; CONTROLLED STUDY; FEMALE; FIBROBLAST; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; IN VITRO STUDY; KIDNEY BIOPSY; KIDNEY CELL; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY INJURY; KIDNEY INTERSTITIUM; KIDNEY TUBULE; KIDNEY TUBULOINTERSTITIAL FIBROSIS; MONOCYTE; MOUSE; NEPHRITIS; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN SYNTHESIS; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; UNILATERAL URETERAL OBSTRUCTION; URETER OBSTRUCTION;

ANIMALS; BIOPSY; CELL LINE; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; FEMALE; FIBROSIS; HUMANS; INFLAMMATION; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; KIDNEY; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEPHRITIS, INTERSTITIAL; RATS; RECEPTOR, NOTCH1; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; URETERAL OBSTRUCTION;

EID: 84867571003     PISSN: 00223417     EISSN: 10969896     Source Type: Journal    
DOI: 10.1002/path.4076     Document Type: Article

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