Structure of Naegleria Tet-like dioxygenase (NgTet1) in complexes with a reaction intermediate 5-hydroxymethylcytosine DNA

Nucleic Acids Research

Volumn 43, Issue 22, 2015, Pages 10713-10721

  Hashimoto, Hideharu ^a   Pais, June E ^b   Dai, Nan ^b   Corrêa, Ivan R ^b   Zhang, Xing ^a   Zheng, Yu ^c   Cheng, Xiaodong ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NEW ENGLAND BIOLABS   (United States)

^c RGENE Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2 OXOGLUTARIC ACID; 5 CARBOXYLCYTOSINE; 5 FORMYLCYTOSINE; 5 HYDROXYMETHYLCYTOSINE; ALANINE; DIOXYGENASE; DNA; FERROUS ION; HYDROGEN; HYDROXYL GROUP; OXYGEN; PHENYLALANINE; TET LIKE DIOXYGENASE; THYMINE; UNCLASSIFIED DRUG; VALINE; 5 METHYLCYTOSINE; 5-HYDROXYMETHYLCYTOSINE; CYTOSINE;

AEROBIC METABOLISM; ARTICLE; BINDING AFFINITY; COMPLEX FORMATION; CONFORMATION; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; ENZYME SUBSTRATE; HYDROPHOBICITY; HYDROXYLATION; LIQUID CHROMATOGRAPHY; NAEGLERIA GRUBERI; NONHUMAN; PRIORITY JOURNAL; SITE DIRECTED MUTAGENESIS; TANDEM MASS SPECTROMETRY; AMINO ACID SUBSTITUTION; ANALOGS AND DERIVATIVES; CHEMISTRY; ENZYMOLOGY; GENETICS; MOLECULAR MODEL; NAEGLERIA;

5-METHYLCYTOSINE; AMINO ACID SUBSTITUTION; CATALYTIC DOMAIN; CYTOSINE; DIOXYGENASES; DNA; MODELS, MOLECULAR; NAEGLERIA; THYMINE;

EID: 84962428929     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkv870     Document Type: Article

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