Glycan modification of antigen alters its intracellular routing in dendritic cells, promoting priming of T cells

eLife

Volumn 5, Issue MARCH2016, 2016, Pages

  Streng Ouwehand, Ingeborg ^a   Ho, Nataschja I ^b   Litjens, Manja ^a   Kalay, Hakan ^a   Boks, Martine Annemarie ^a   Cornelissen, Lenneke A M ^a   Singh, Satwinder Kaur ^a   Saeland, Eirikur ^a   Garcia Vallejo, Juan J ^a   Ossendorp, Ferry A ^b   Unger, Wendy W J ^a,c   van Kooyk, Yvette ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^c ERASMUS MEDICAL CENTER   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

CATHEPSIN S; GLYCAN; LECTIN RECEPTOR; OVALBUMIN; T LYMPHOCYTE ANTIGEN; ANTIGEN; ASIALOGLYCOPROTEIN; LECTIN; MEMBRANE PROTEIN; MGL1 PROTEIN, MOUSE; POLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIFFERENTIATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CROSS PRESENTATION; DENDRITIC CELL; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GLYCOSYLATION; IMMUNE RESPONSE; INTRACELLULAR SIGNALING; MATRIX ASSISTED LASER DESORPTION IONIZATION TIME OF FLIGHT MASS SPECTROMETRY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PH; PROTEIN MODIFICATION; REAL TIME POLYMERASE CHAIN REACTION; REVERSED PHASE LIQUID CHROMATOGRAPHY; ANIMAL; CHEMISTRY; DEFICIENCY; IMMUNOLOGY; KNOCKOUT MOUSE; METABOLISM; PROTEIN TRANSPORT; T LYMPHOCYTE;

ANIMALS; ANTIGENS; ASIALOGLYCOPROTEINS; DENDRITIC CELLS; LECTINS, C-TYPE; MEMBRANE PROTEINS; MICE; MICE, KNOCKOUT; OVALBUMIN; POLYSACCHARIDES; PROTEIN TRANSPORT; T-LYMPHOCYTES;

EID: 84962281541     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.11765     Document Type: Article

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