Binding sites for Lewis antigens are expressed by human colon cancer cells and negatively affect their migration

Laboratory Investigation

Volumn 83, Issue 6, 2003, Pages 777-787

  Hittelet, Axel ^a   Camby, Isabelle ^b   Nagy, Nathalie ^a   Legendre, Hugues ^c   Bronckart, Yves ^b   Decaestecker, Christine ^b   Kaltner, Herbert ^d   Nifant'ev, Nikolay E ^e   Bovin, Nicolai V ^f   Pector, Jean Claude ^c   Salmon, Isabelle ^a   Gabius, Hans Joachim ^d   Kiss, Robert ^b   Yeaton, Paul ^g  

^a ERASME HOSPITAL   (Belgium)

^b UNIVERSITÉ LIBRE DE BRUXELLES   (Belgium)

^c JULES BORDET INSTITUTE   (Belgium)

^d UNIVERSITY OF MUNICH   (Germany)

^e N D ZELINSKY INSTITUTE OF ORGANIC CHEMISTRY   (Russian Federation)

^f SHEMYAKIN OVCHINNIKOV INSTITUTE OF BIOORGANIC CHEMISTRY   (Russian Federation)

^g UNIVERSITY OF VIRGINIA HEALTH SYSTEM   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD GROUP ANTIGEN; CALCIUM; CARBOHYDRATE; EPITOPE; GLYCOCONJUGATE; LEWIS A ANTIGEN; LEWIS X ANTIGEN; LIGAND; MATRIGEL; OLIGOSACCHARIDE; SELECTIN; SIALYL LEWIS A ANTIGEN; SIALYL LEWIS X ANTIGEN; SUGAR; SYNTHETIC NEOGLYCOCONJUGATE; UNCLASSIFIED DRUG;

ADOLESCENT; ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ANTIGEN BINDING; ANTIGEN PRESENTATION; ARTICLE; BINDING SITE; BLOOD GROUP LEWIS SYSTEM; CANCER CELL; CELL ADHESION; CELL MIGRATION; COLON CANCER; COMPUTER ASSISTED PHASE CONTRAST VIDEOMICROSCOPY; CULTURE MEDIUM; ENDOTHELIUM CELL; FEMALE; GENE EXPRESSION; HISTOCHEMISTRY; IMMUNOCYTOCHEMISTRY; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; NUDE MOUSE; PHASE CONTRAST MICROSCOPY; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; TUMOR XENOGRAFT;

EID: 12444342663     PISSN: 00236837     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.LAB.0000073129.62433.39     Document Type: Article

References (55)

1. André S, Cejas Ortega PJ, Alamino Perez M, Roy R, and Gabius HJ (1999). Lactose-containing starburst dendrimers: Influence of dendrimer generation and binding-site orientation of receptors (plant/animal lectins and immunoglobulins) on binding properties. Glycobiology 9:1253-1261.
2. André S, Pieters RJ, Vrasidas I, Kaltner H, Kuwabara I, Liu FT, Liskamp RMJ, and Gabius HJ (2001). Wedgelike glycodendrimers as inhibitors of binding of mammalian galectins to glycoproteins, lactose maxiclusters and cell surface glycoconjugates. Chembiochem 2:822-830.
3. Angata T and Varki A (2002). Chemical diversity in the sialic acids and related α-keto acids: An evolutionary perspective. Chem Rev 102:439-469.
4. Baldus SE, Monig SP, Hanisch FG, Zirbes TK, Flucke U, Oelert S, Zilkens G, Madejczik B, Thiele J, Schneider PM, Holscher AH, and Dienes HP (2002). Comparative evaluation of the prognostic value of MUC1, MUC2, sialyl-Lewis(a) and sialyl-Lewis(x) antigens in colorectal adenocarcinoma. Histopathology 40:440-449.
5. Biancone L, Araki M, Araki K, Vassalli P, and Stamenkovic I (1996). Redirection of tumor metastasis by expression of E-selectin in vivo. J Exp Med 183:581-587.
6. Bovin NV and Gabius HJ (1995). Polymer-immobilized carbohydrate ligands: Versatile chemical tools for biochemistry and medical sciences. Chem Soc Rev 24:413-421.
7. Brodt P, Fallavollita L, Bresalier RS, Meterissian S, Norton CR, and Wolitzky BA (1997). Liver endothelial E-selectin mediates carcinoma cell adhesion and promotes liver metastasis. Int J Cancer 71:612-619.
8. Camby I, Nagy N, Lopes MB, Schafer BW, Maurage CA, Ruchoux MM, Murmann P, Pochet R, Heizmann CW, Brotchi J, Salmon I, Kiss R, and Decaestecker C (1999). Supratentorial pilocytic astrocytomas, astrocytomas, anaplastic astrocytomas and glioblastomas are characterized by a differential expression of S100 proteins. Brain Pathol 9:1-19.
9. Danguy A, Decaestecker C, Genten F, Salmon I, and Kiss R (1998). Application of lectins and neoglycoconjugates in histology and pathology. Acta Anat 161:206-218.
10. De Hauwer C, Camby I, Darro F, Decaestecker C, Gras T, Salmon I, Kiss R, and Van Ham P (1997). Dynamic characterization of glioblastoma cell motility. Biochem Biophys Res Commun 232:267-272.
11. De Hauwer C, Camby I, Darro F, Migeotte I, Decaestecker C, Verbeek C, Danguy A, Pasteels, JL, Brotchi J, Salmon I, Van Ham P, and Kiss R (1998). Gastrin inhibits motility, decreases cell death and increases proliferation in human glioblastoma cell lines. J Neurobiol 37:373-382.
12. Delbrouck C, Doyen I, Belot N, Decaestecker C, Ghanooni R, de Lavareille A, Kaltner H, Choufani G, Danguy A, Vandenhoven G, Gabius HJ, Hassid S, and Kiss R (2002). Galectin-1 is overexpressed in nasal polyps under budesonide and inhibits eosinophil migration. Lab Invest 82:147-158.
13. Dell A, Morris HR, Easton RL, Patankast M, and Clark GF (1999). The glycobiology of gametes and fertilization. Biochim Biophys Acta 1473:196-205.
14. Etzioni A and Tonetti M (2000). Leukocyte adhesion deficiency II: from A to almost Z. Immunol Rev 178:138-147.
15. x oligosaccharide. J Cell Biol 117:895-902.
16. Freeze HH (2001). Updates and perspectives on congenital disorders of glycosylation. Glycobiology 11:129R-143R.
17. Fukuda M (1995). Carbohydrate-dependent cell adhesion. Biorg Med Chem 3:207-215.
18. x oligosaccharides: Versatile roles in cell-cell interaction. J Cell Biol 147:467-470.
19. Gabius HJ (1997). Concepts of tumor lectinology. Cancer Invest 15:454-464.
20. Gabius HJ (2000). Biological information transfer beyond the genetic code: The sugar code. Naturwissenschaften 87:108-121.
21. Gabius HJ (2001). Glycohistochemistry: The why and how of detection and localization of endogenous lectins. Anat Histol Embryol 30:3-31.
22. Gabius HJ and Bardosi A (1991). Neoglycoproteins as tools in glycohistochemistry. Prog Histochem Cytochem 22:1-66.
23. Gabius HJ, Gabius S, Zemlyanukhina TV, Bovin NV, Brinck U, Danguy A, Joshi SS, Kayser K, Schottelius J, Sinowatz F, Tietze LF, Vidal-Vanaclocha F, and Zanetta JP (1993). Reverse lectin histochemistry: Design and application of glycoligands for detection of cell and tissue lectins. Histol Histopathol 8:369-383.
24. Gabius HJ and Vehmeyer K (1988). Effect of microenvironment and cell-line type on carbohydrate-binding proteins of macrophage-like cells. Biochem Cell Biol 66:1169-1176.
25. Goldschmidt D, Decaestecker C, Berthe JV, Gordower L, Remmelink M, Danguy A, Pasteels JL, Salmon I, and Kiss R (1996). The contribution of image cytometry and artificial intelligence-related methods of numerical data analysis for adipose tumor histopathologic classification. Lab Invest 75:295-306.
26. Jannot MC, Kruczynski A, Limouzy A, Dangou JM, Selves J, Delsol G, Martinez J, and Kiss R (1993). Spontaneous evolution of cytoplasmic lectin binding and nuclear size and deoxyribonucleic acid content in human colorectal cancers grafted onto nude mice. Lab Invest 68:446-455.
27. Kansas GS (1996). Selectins and their ligands: Current concepts and controversies. Blood 88:3259-3287.
28. Kaji M, Ishikura H, Kishimoto T, Omi M, Ishizu A, Kimura C, Takahashi T, Kato H, and Yoshiki T (1995). E-selectin expression induced by pancreas-carcinoma-derived interleukin aα results in enhanced adhesion of pancreas carcinoma cells to endothelial cells. Int J Cancer 60:712-717.
29. Kaltner H and Stierstorfer B (1998). Animal lectins as cell adhesion molecules. Acta Anat 161:162-179.
30. Kannagi R (1997). Carbohydrate-mediated cell adhesion involved in hematogenous metastasis of cancer. Glycoconjugate J 14:577-584.
31. Khatib AM, Kontogiannea M, Fallavollita L, Jamison B, Meterissian S, and Brodt P (1999). Rapid induction of cytokine and E-selectin expression in the liver in response to metastatic tumor cells. Cancer Res 59:1356-1361.
32. Kobayashi K, Matsumoto S, Morishima T, Kawabe T, and Okamoto T (2000). Cimetidine inhibits cancer cell adhesion to endothelial cells and prevents metastasis by blocking E-selectin expression. Cancer Res 60:3978-3984.
33. Krause T and Turner GA (1999). Are selectins involved in metastasis? Clin Exp Metastasis 17:183-192.
34. Listinsky JJ, Siegal GP, and Listinsky CM (1998). α-L-fucose: A potentially critical molecule in pathologic processes including neoplasia. Am J Clin Pathol 110:425-440.
35. Matsumoto S, Imaeda Y, Umemoto S, Kobayashi K, Suzuki H, and Okamoto T (2002). Cimetidine increases survival of colorectal cancer patients with high levels of sialyl Lewis-X and sialyl Lewis-A epitope expression on tumour cells. Br J Cancer 86:161-167.
36. Muramatsu T (1993). Carbohydrate signals in metastasis and prognosis of human carcinomas. Glycobiology 3:291-296.
37. Nagy N, Brenner C, Markadieu N, Chaboteaux C, Camby I, Schäfer BW, Pochet R, Heizmann CW, Salmon I, Kiss R, and Decaestecker C (2001). S100A2, a putative tumor suppressor gene, regulates in vitro squamous cell carcinoma migration. Lab Invest 81:599-612.
38. x antigen correlates with poor survival in patients with colorectal carcinoma: Clinicopathological and immunohistochemical study. Cancer Res 53:3632-3637.
39. Nifant'ev NE, Tsvetkov YE, Shashkov AS, Kononov LO, Menshov VM, Tuzikov AB, and Bovin NV (1996). Selectin receptors: Synthesis of tetrasaccharides sialyl Lewis A and sialyl Lewis X containing a spacer group. J Carbohydr Chem 15:939-953.
40. x, and their polymer conjugates. Rus J Bioorgan Chem 20:311-314.
41. x oligosaccharides. Proc Natl Acad Sci USA 99:13789-13794.
42. x oligosaccharides in tumor metastasis and rejection by natural killer cells. EMBO J 18:1516-1525.
43. Reuter G and Gabius HJ (1999). Eukaryotic glycosylation: Whim of nature or multipurpose tool? Cell Mol Life Sci 55:368-422.
44. Sanders WJ, Gordon EJ, Dwir O, Beck PJ, Alon R, and Kiessling RR (1999). Inhibition of L-selectin-mediated leukocyte rolling by synthetic glycoprotein mimics. J Biol Chem 274:5271-5278.
45. Simanek EE, McGarvey GJ, Jablonowski JA, and Wong CH (1998). Selectin-carbohydrate interactions: From natural ligands to designed mimics. Chem Rev 98:833-862.
46. Takada A, Ohmori K, Takahashi N, Tsuyuoka K, Yago A, Zenita K, Hasegawa A, and Kannagi R (1991). Adhesion of human cancer cells to vascular endothelium mediated by a carbohydrate antigen, sialyl Lewis A. Biochem Biophys Res Commun 179:713-719.
47. Tedder TF, Steeber DA, Chen A, and Engel P (1995). The selectins: Vascular adhesion molecules. FASEB J 9:866-873.
48. Tozeren A, Kleinman HK, Grant DS, Morales D, Mercurio AM, and Byers SW (1995). E-selectin-mediated dynamic interactions of breast- and colon-cancer cells with endothelial-cell monolayers. Int J Cancer 60:426-431.
49. Varki A (1997). Sialic acids as ligands in recognition phenomena. FASEB J 11:248-255.
50. Vestweber D and Blanks JE (1999). Mechanisms that regulate the function of the selectins and their ligands. Physiol Rev 79:181-213.
51. Welply JK, Abbas SZ, Scudder P, Keene JL, Broschat K, Casnocha S, Gorka C, Steininger C, Howard SC, Schmuke JJ, Graneto M, Rotsaert JM, Manger ID, and Jacob GS (1994). Multivalent sialyl-LeX: Potent inhibitors of E-selectinmediated cell adhesion; reagent for staining activated endothelial cells. Glycobiology 4:259-265.
52. Weston BW, Hiller KM, Mayben JP, Manousos GA, Bendt KM, Liu R, and Cusack JC Jr (1999). Expression of human α (1,3) fucosyltransferase antisense sequences inhibits selectin-mediated adhesion and liver metastasis of colon carcinoma cells. Cancer Res 59:2127-2135.
53. Yamazaki N, Kojima S, Bovin NV, André S, Gabius S, and Gabius HJ (2000). Endogenous lectins as targets for drug delivery. Adv Drug Deliv Rev 43:225-244.
54. Yoshitani N, Mori E, and Takasaki S (2001). Detection of carbohydrate recognition molecules on the plasma membrane of boat sperm by dextran-based multivalent oligosaccharide probes. Glycobiology 11:313-320.
55. Zhang J, Nakayama J, Ohyama C, Suzuki M, Suzuki A, Fukuda M, and Fukuda MN (2002). Sialyl Lewis X-dependent lung colonization of B16 melanoma cells through a selectinlike endothelial receptor distinct from E- and P-selectin. Cancer Res 62:4194-4198.