Glycan-modified liposomes boost CD4 + and CD8 + T-cell responses by targeting DC-SIGN on dendritic cells

Journal of Controlled Release

Volumn 160, Issue 1, 2012, Pages 88-95

  Unger, Wendy W J ^a   Van Beelen, Astrid J ^a   Bruijns, Sven C ^a   Joshi, Medha ^b,d   Fehres, Cynthia M ^a   Van Bloois, Louis ^b   Verstege, Marleen I ^a   Ambrosini, Martino ^a   Kalay, Hakan ^a   Nazmi, Kamran ^c   Bolscher, Jan G ^c   Hooijberg, Erik ^a   De Gruijl, Tanja D ^a   Storm, Gert ^b   Van Kooyk, Yvette ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b UTRECHT UNIVERSITY   (Netherlands)

^c UNIVERSITY OF AMSTERDAM   (Netherlands)

^d MIDWESTERN UNIVERSITY   (United States)

Author keywords

Anti tumor immunity; Antigen targeting; CD4 T cells; CD8 T cells; DC SIGN; Glycans

Indexed keywords

ANTIGEN-TARGETING; ANTITUMOR IMMUNITY; DC-SIGN; GLYCANS; T CELLS;

ANTIGENS; CARBOHYDRATES; CYTOLOGY; DISEASES; LIPOSOMES; OLIGOMERS; PATIENT TREATMENT; TUMORS; VACCINES;

CELLS;

C TYPE LECTIN RECEPTOR; CANCER VACCINE; CD209 ANTIGEN; GAMMA INTERFERON; GLYCAN; IMMUNOLIPOSOME; LECTIN RECEPTOR; MELANOMA ANTIGEN 1; SIALYL LEWIS X ANTIGEN; TETRAMER; TUMOR ANTIGEN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIGEN BINDING; ANTIGEN PRESENTATION; ARTICLE; BLOOD GROUP LEWIS SYSTEM; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELLULAR IMMUNITY; CHEMICAL MODIFICATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DENDRITIC CELL; DISPERSION; DRUG FORMULATION; EFFECTOR CELL; HUMAN; HUMAN CELL; INTERNALIZATION; LYMPHOCYTE CLONE; LYMPHOCYTE DIFFERENTIATION; MOUSE; NONHUMAN; PARTICLE SIZE; PRIORITY JOURNAL; T LYMPHOCYTE ACTIVATION; ZETA POTENTIAL;

ANIMALS; ANTIGEN PRESENTATION; ANTIGENS, NEOPLASM; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL ADHESION MOLECULES; DENDRITIC CELLS; DRUG DELIVERY SYSTEMS; HUMANS; LECTINS, C-TYPE; LIPOSOMES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; POLYSACCHARIDES; RECEPTORS, CELL SURFACE;

EID: 84861532469     PISSN: 01683659     EISSN: 18734995     Source Type: Journal    
DOI: 10.1016/j.jconrel.2012.02.007     Document Type: Article

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