Selective membrane disruption by the cyclotide kalata B7: Complex ions and essential functional groups in the phosphatidylethanolamine binding pocket

Biochimica et Biophysica Acta - Biomembranes

Volumn 1858, Issue 6, 2016, Pages 1317-1327

  Strömstedt, Adam A ^a   Kristiansen, Per Eugen ^b   Gunasekera, Sunithi ^a   Grob, Nathalie ^a   Skjeldal, Lars ^c   Göransson, Ulf ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b UNIVERSITY OF OSLO   (Norway)

^c NORWEGIAN UNIVERSITY OF LIFE SCIENCES   (Norway)

Author keywords

Antimicrobial peptide; Cyclotide; Liposome; Membrane permeabilization; Peptide membrane interaction; Phosphatidylethanolamine binding

Indexed keywords

ALANINE; CALCIUM; CYCLOTIDE; DIVALENT CATION; KALATA B1; KALATA B2; KALATA B7; LIPOSOME; MAGNESIUM; MANGANESE; PHENYLALANINE; PHOSPHATIDYLETHANOLAMINE; PHOSPHOLIPID; SERINE; SODIUM CHLORIDE; TYROSINE; UNCLASSIFIED DRUG; ION;

AMINO ACID SUBSTITUTION; ARTICLE; BINDING COMPETITION; CONTROLLED STUDY; MEMBRANE DAMAGE; MEMBRANE PERMEABILITY; NUCLEAR MAGNETIC RESONANCE; POINT MUTATION; PRIORITY JOURNAL; CELL MEMBRANE; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY;

CELL MEMBRANE; CYCLOTIDES; IONS; MAGNETIC RESONANCE SPECTROSCOPY; MASS SPECTROMETRY; MODELS, MOLECULAR; PHOSPHATIDYLETHANOLAMINES;

EID: 84962206529     PISSN: 00052736     EISSN: 18792642     Source Type: Journal    
DOI: 10.1016/j.bbamem.2016.02.013     Document Type: Article

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