Making ends meet: Microwave-accelerated synthesis of cyclic and disulfide rich proteins via in situ thioesterification and native chemical ligation

International Journal of Peptide Research and Therapeutics

Volumn 19, Issue 1, 2013, Pages 43-54

  Gunasekera, Sunithi ^a   Aboye, Teshome L ^a   Madian, Walid A ^a,b   El Seedi, Hesham R ^a,b   Göransson, Ulf ^a  

^a UPPSALA UNIVERSITY   (Sweden)

^b Menoufia University   (Egypt)

Author keywords

Cyclotide; Di Fmoc 3,4 diaminobenzoic acid; Fmoc SPPS; kalata B1; Microwave assisted peptide synthesis; Native chemical ligation; SFTI 1

Indexed keywords

ARGININE; CYCLOPEPTIDE; DEFENSIN; GLYCINE; ISOLEUCINE; KALATA B1 PEPTIDE; O (7 AZABENZOTRIAZOL 1 YL) N,N,N',N' TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE; O (BENZOTRIAZOL 1 YL) N,N,N',N' TETRAMETHYLURONIUM HEXAFLUOROPHOSPHATE; REAGENT; RESIN; SERINE; SUNFLOWER TRYPSIN INHIBITOR 1 PEPTIDE; THIOESTER; UNCLASSIFIED DRUG;

AMINO TERMINAL SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CHEMICAL MODIFICATION; ESTERIFICATION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN SITU THIOESTERIFICATION; MICROWAVE ACCELERATED SYNTHESIS; NATIVE CHEMICAL LIGATION; PEPTIDE SYNTHESIS; PROCESS OPTIMIZATION; PROTEIN ASSEMBLY; PROTEIN PURIFICATION; SOLID PHASE SYNTHESIS;

HELIANTHUS;

EID: 84875228022     PISSN: 15733149     EISSN: 15733904     Source Type: Journal    
DOI: 10.1007/s10989-012-9331-y     Document Type: Article

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