Polybrominated diphenyl ether exposure and thyroid function tests in North American adults

Environmental Health Perspectives

Volumn 124, Issue 4, 2016, Pages 420-425

  Makey, Colleen M ^a   McClean, Michael D ^a   Braverman, Lewis E ^b   Pearce, Elizabeth N ^b   He, Xue Mei ^b   Sjödin, Andreas ^c   Weinberg, Janice M ^a   Webster, Thomas F ^a  

^a BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^b BOSTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CENTER FOR ENVIRONMENTAL HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2,2',4,4' TETRABROMODIPHENYL ETHER; CHOLESTEROL; IODIDE; LIOTHYRONINE; PERCHLORATE; POLYBROMINATED DIPHENYL ETHER; THYROID PEROXIDASE ANTIBODY; THYROTROPIN; THYROXINE; TRIACYLGLYCEROL; DIPHENYL ETHER DERIVATIVE; ENDOCRINE DISRUPTOR; FLAME RETARDANT; POLYBROMINATED BIPHENYL; THYROID HORMONE;

ADULT; ARTICLE; BLOOD ANALYSIS; COHORT ANALYSIS; COLORIMETRY; DRUG EXPOSURE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; HUMAN; ION CHROMATOGRAPHY; LIMIT OF DETECTION; MALE; MASS SPECTROMETRY; NORMAL HUMAN; NORTH AMERICAN; OFFICE WORKER; PRIORITY JOURNAL; THYROID FUNCTION TEST; URINALYSIS; BLOOD; ENVIRONMENTAL EXPOSURE; MASSACHUSETTS; MIDDLE AGED; OCCUPATIONAL EXPOSURE; SEASON;

ADULT; BOSTON; ENDOCRINE DISRUPTORS; ENVIRONMENTAL EXPOSURE; FEMALE; FLAME RETARDANTS; HALOGENATED DIPHENYL ETHERS; HUMANS; MALE; MIDDLE AGED; OCCUPATIONAL EXPOSURE; POLYBROMINATED BIPHENYLS; SEASONS; THYROID FUNCTION TESTS; THYROID HORMONES; THYROTROPIN;

EID: 84962159652     PISSN: 00916765     EISSN: 15529924     Source Type: Journal    
DOI: 10.1289/ehp.1509755     Document Type: Article

References (47)

1. Abdelouahab N, Langlois MF, Lavoie L, Corbin F, Pasquier JC, Takser L. 2013. Maternal and cordblood thyroid hormone levels and exposure to polybrominated diphenyl ethers and polychlorinated biphenyls during early pregnancy. Am J Epidemiol 178(5):701-713.
2. Andersen S, Pedersen KM, Bruun NH, Laurberg P. 2002. Narrow individual variations in serum T4 and T3 in normal subjects: a clue to the understanding of subclinical thyroid disease. J Clin Endocrinol Metab 87(3):1068-1072.
3. Benvenga S. 2013. Thyroid hormone transport proteins and the physiology of hormone binding. In: Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text. 10th Edition (Braverman LE, Cooper GS., eds). Philadelphia, PA:Lippincott Williams and Wilkins, 99-103.
4. Blake CA, McCoy GL, Hui YY, LaVoie HA. 2011. Perinatal exposure to low-dose DE-71 increases serum thyroid hormones and gonadal osteopontin gene expression. Exp Biol Med (Maywood) 236(4):445-455.
5. Bianco AC, Kim BW. 2013. Intracellular pathways of iodothryonine matabolism/implications of deiodinaton for thyroid hormone action. In: Werner & Ingbar's The Thyroid: A Fundamental and Clinical Text. 10th Edition (Braverman LE, Cooper GS., eds). Philadelphia, PA:Lippincott Williams and Wilkins, 104-126.
6. Blanco J, Mulero M, Heredia L, Pujol A, Domingo JL, Sánchez DJ. 2013. Perinatal exposure to BDE-99 causes learning disorders and decreases serum thyroid hormone levels and BDNF gene expression in hippocampus in rat offspring. Toxicology 308:122-128.
7. Bloom M, Spliethoff H, Vena J, Shaver S, Addink R, Eadon G. 2008. Environmental exposure to PBDEs and thyroid function among New York anglers. Environ Toxicol Pharmacol 25(3):386-392.
8. Blount BC, Pirkle JL, Osterloh JD, Valentin-Blasini L, Caldwell KL. 2006. Urinary perchlorate and thyroid hormone levels in adolescent and adult men and women living in the United States. Environ Health Perspect 114:1865-1871, doi:10.1289/ehp.9466.
9. Chevrier J. 2013. Invited commentary: maternal plasma polybrominated diphenyl ethers and thyroid hormones-challenges and opportunities. Am J Epidemiology 178(5):714-19.
10. Chevrier J, Harley KG, Bradman A, Gharbi M, Sjödin A, Eskenazi B. 2010. Polybrominated diphenyl ether (PBDE) flame retardants and thyroid hormone during pregnancy. Environ Health Perspect 118:1444-1449, doi:10.1289/ehp.1001905.
11. Chevrier J, Harley KG, Bradman A, Sjödin A, Eskenazi B. 2011. Prenatal exposure to polybrominated diphenyl ether flame retardants and neonatal thyroid-stimulating hormone levels in the CHAMACOS study. Am J Epidemiol 174(10):1166-1174.
12. Choksi NY, Jahnke GD, St. Hilaire C, Shelby M. 2003. Role of thyroid hormones in human and laboratory animal reproductive health. Birth Defects Res B Dev Reprod Toxicol 68:479-491.
13. Cooper DS, Biondi R. 2012. Subclinical thyroid disease. Lancet 379(9821):1142-1154.
14. De Groot L, Abalovich M, Alexander EK, Amino N, Barbour L, Cobin RH, et al. 2012. Management of thyroid dysfunction during pregnancy and postpartum: an Endocrine Society clinical practice guideline. J Clin Endocrinol Metab 97(8):2543-2565.
15. Dishaw LV, Macaulay LJ, Roberts SC, Stapleton HM. 2014. Exposures, mechanisms, and impacts of endocrine-active flame retardants. Curr Opin Pharmacol 19:125-133.
16. Ellis-Hutchings RG, Cherr GN, Hanna LA, Keen CL. 2006. Polybrominated diphenyl ether (PBDE)-induced alterations in vitamin A and thyroid hormone concentrations in the rat during lactation and early postnatal development. Toxicol Appl Pharmacol 215(2):135-145.
17. Ernest SR, Wade MG, Lalancette C, Ma YQ, Berger RG, Robaire B, et al. 2012. Effects of chronic exposure to an environmentally relevant mixture of brominated flame retardants on the reproductive and thyroid system in adult male rats. Toxicol Sci 127(2):496-507.
18. Fowles JR, Fairbrother A, Baecher-Steppan L, Kerkvliet NI. 1994. Immunologic and endocrine effects of the flame-retardant pentabromodiphenyl ether (DE-71) in C57BL/6J mice. Toxicology 86(1-2):49-61.
19. Fraser AJ, Webster TF, McClean MD. 2009. Diet contributes significantly to the body burden of PBDEs in the general U.S. population. Environ Health Perspect 117:1520-1525, doi:10.1289/ehp.0900817.
20. Garber JR, Cobin RH, Gharib H, Hennessey JV, Klein I, Mechanick JI, et al. 2012. Clinical practice guidelines for hypothyroidism in adults: cosponsored by the American Association of Clinical Endocrinologists and the American Thyroid Association. Thyroid 22(12):1200-1235.
21. He P, Wang A, Niu Q, Guo L, Xia T, Chen X. 2011. Toxic effect of PBDE-47 on thyroid development, learning, and memory, and the interaction between PBDE-47 and PCB153 that enhances toxicity in rats. Toxicol Ind Health 27(3):279-288.
22. Herbstman JB, Sjödin A, Apelberg BJ, Witter FR, Halden RU, Patterson DG, et al. 2008. Birth delivery mode modifies the associations between prenatal polychlorinated biphenyl (PCB) and polybrominated diphenyl ether (PBDE) and neonatal thyroid hormone levels. Environ Health Perspect 116:1376-1382, doi:10.1289/ehp.11379.
23. Kodavanti PR, Coburn CG, Moser VC, MacPhail RC, Fenton SE, Stoker TE, et al. 2010. Developmental exposure to a commercial PBDE mixture, DE-71: neurobehavioral, hormonal, and reproductive effects. Toxicol Sci 116(1):297-312.
24. Lin SM, Chen FA, Huang YF, Hsing LL, Chen LL, Wu LS, et al. 2011. Negative associations between PBDE levels and thyroid hormones in cord blood. Int J Hyg Environ Health 214(2):115-120.
25. Little RJA, Rubin DB. 2002. Statistical Analysis with Missing Data. 2nd ed. Hoboken, NJ:Wiley.
26. Makey CM, McClean MD, Sjödin A, Weinberg J, Carignan CC, Webster TF. 2014. Temporal variability of polybrominated diphenyl ether (PBDE) serum concentrations over one year. Environ Sci Tech 48(24):14642-14649, doi:10.1021/es5026118.
27. Marchesini GR, Meimaridou A, Haasnoot W, Meulenberg E, Albertus F, Mizuguchi M, et al. 2008. Biosensor discovery of thyroxine transport disrupting chemicals. Toxicol Appl Pharmacol 232(1):150-160.
28. Meerts IA, van Zanden JJ, Luijks EAC, van Leeuwen-Bol I, Marsh G, Jakobsson E, et al. 2000. Potent competitive interactions of some brominated flame retardants and related compounds with human transthyretin in vitro. Toxicol Sci 56(1):95-104.
29. Pearce EN. 2012. Update in lipid alterations in subclinical hypothyroidism. J Clin Endocrinol Metab 97(2):326-333.
30. Phillips DL, Pirkle JL, Burse VW, Bernert JT Jr, Henderson LO, Needham, LL. 1989. Chlorinated hydrocarbon levels in human serum: effects of fasting and feeding. Arch Environ Contam Toxicol 18:495-500.
31. Richardson VM, Staskal DF, Ross DG, Diliberto JJ, DeVito MJ, Birnbaum LS. 2008. Possible mechanisms of thyroid hormone disruption in mice by BDE 47, a major polybrominated diphenyl ether congener. Toxicol Appl Pharmacol 226(3):244-250.
32. Schecter A, Haffner D, Colacino J, Patel K, Päpke O, Opel M, et al. 2010. Polybrominated diphenyl ethers (PBDEs) and hexabromocyclodecane (HBCD) in composite U.S. food samples. Environ Health Perspect 118:357-362, doi:10.1289/ ehp.0901345.
33. Schisterman EF, Whitcomb BW, Louis GM, Louis TA. 2005. Lipid adjustment in the analysis of environmental contaminants and human health risks. Environ Health Perspect 113:853-857, doi:10.1289/ ehp.7640.
34. Sjödin A, Jones RS, Lapeza CR, Focant JF, McGahee EE III, Patterson DG Jr. 2004. Semiautomated high-throughput extraction and cleanup method for the measurement of poly brominated diphenyl ethers, polybrominated biphenyls, and polychlorinated biphenyls in human serum. Anal Chem 76:1921-1927.
35. Stagnaro-Green A, Abalovich M, Alexander E, Azizi F, Mestman J, Negro R, et al. 2011. Guidelines of the American Thyroid Association for the diagnosis and management of thyroid disease during pregnancy and postpartum. Thyroid 21(10):1081-1125.
36. Stapleton HM, Eagle S, Anthopolos R, Wolkin A, Miranda ML. 2011. Associations between polybrominated diphenyl ether (PBDE) flame retardants, phenolic metabolites, and thyroid hormones during pregnancy. Environ Health Perspect 119:1454-1459, doi:10.1289/ehp.1003235.
37. Stockholm Convention. 2004. Decisions and Recommendations: Listing of tetrabromodiphenyl ether and pentabromodiphenyl ether. Available: http://chm.pops.int/Implementation/NewPOPs/ DecisionsRecommendations/tabid/671/ctl/Download/ mid/8120/Default.aspx?id=101&ObjID=7673 [accessed 14 August 2015].
38. Stockigt JR, Lim CF. 2009. Medications that distort in vitrotests of thyroid function, with particular reference to estimates of serum free thyroxine. Best Pract Res Clin Endocrinol Metab 23(6):753-767.
39. Stoker TE, Laws SC, Crofton KM, Hedge JM, Ferrell JM, Cooper RL. 2004. Assessment of DE-71, a commercial polybrominated diphenyl ether (PBDE) mixture, in the EDSP male and female pubertal protocols. Toxicol Sci 78(1):144-155.
40. Turyk ME, Persky VW, Imm P, Knobeloch L, Chatterton R, Anderson HA. 2008. Hormone disruption by PBDEs in adult male sport fish consumers. Environ Health Perspect 116:1635-1641, doi:10.1289/ ehp.11707.
41. Valentin-Blasini L, Mauldin JP, Maple D, Blount BC. 2005. Analysis of perchlorate in human urine using ion chromatography and electrospray tandem mass spectrometry. Anal Chem 77(8):2475-2481
42. van der Ven LT, van de Kuil T, Verhoef A, Leonards PE, Slob W, Cantón RF, et al. 2008. A 28-day oral dose toxicity study enhanced to detect endocrine effects of a purified technical pentabromodiphenyl ether (pentaBDE) mixture in Wistar rats. Toxicology 245(1-2):109-122.
43. Watkins DJ, McClean MD, Fraser AJ, Weinberg J, Stapleton HM, Sjödin A, et al. 2012. Impact of dust from multiple microenvironments and diet on PentaBDE body burden. Environ Sci Technol 46(2):1192-1200.
44. WHO (World Health Organization). 2013. Urinary Iodine Concentrations for Determining Iodine Status Deficiency in Populations. Available: http://apps. who.int/iris/bitstream/10665/85972/1/WHO_NMH_ NHD_EPG_13.1_eng.pdf [accessed 11 February 2014].
45. Zhou T, Ross DG, DeVito MJ, Crofton KM. 2001. Effects of short-term in vivo exposure to polybrominated diphenyl ethers on thyroid hormones and hepatic enzyme activities in weanling rats. Toxicol Sci 61(1):76-82.
46. Zhou T, Taylor MM, DeVito MJ, Crofton KM. 2002. Developmental exposure to brominated diphenyl ethers results in thyroid hormone disruption. Toxicol Sci 66(1):105-116.
47. Zota AR, Park JS, Wang Y, Petreas M, Zoeller RT, Woodruff TJ. 2011. Polybrominated diphenyl ethers, hydroxylated polybrominated diphenyl ethers, and measures of thyroid function in second trimester pregnant women in California. Environ Sci Technol 45(18):7896-7905.