-
2
-
-
84875225339
-
Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer
-
Heo, J, Reid, T, Ruo, L, Breitbach, CJ, Rose, S, Bloomston, M et al. (2013). Randomized dose-finding clinical trial of oncolytic immunotherapeutic vaccinia JX-594 in liver cancer. Nat Med 19: 329-336.
-
(2013)
Nat Med
, vol.19
, pp. 329-336
-
-
Heo, J.1
Reid, T.2
Ruo, L.3
Breitbach, C.J.4
Rose, S.5
Bloomston, M.6
-
3
-
-
84859376209
-
Phase I/II trial of carboplatin and paclitaxel chemotherapy in combination with intravenous oncolytic reovirus in patients with advanced malignancies
-
Karapanagiotou, EM, Roulstone, V, Twigger, K, Ball, M, Tanay, M, Nutting, C et al. (2012). Phase I/II trial of carboplatin and paclitaxel chemotherapy in combination with intravenous oncolytic reovirus in patients with advanced malignancies. Clin Cancer Res 18: 2080-2089.
-
(2012)
Clin Cancer Res
, vol.18
, pp. 2080-2089
-
-
Karapanagiotou, E.M.1
Roulstone, V.2
Twigger, K.3
Ball, M.4
Tanay, M.5
Nutting, C.6
-
4
-
-
77955104827
-
Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck
-
Harrington, KJ, Hingorani, M, Tanay, MA, Hickey, J, Bhide, SA, Clarke, PM et al. (2010). Phase I/II study of oncolytic HSV GM-CSF in combination with radiotherapy and cisplatin in untreated stage III/IV squamous cell cancer of the head and neck. Clin Cancer Res 16: 4005-4015.
-
(2010)
Clin Cancer Res
, vol.16
, pp. 4005-4015
-
-
Harrington, K.J.1
Hingorani, M.2
Tanay, M.A.3
Hickey, J.4
Bhide, S.A.5
Clarke, P.M.6
-
5
-
-
80053571003
-
Envelope-chimeric entry-targeted measles virus escapes neutralization and achieves oncolysis
-
Miest, TS, Yaiw, KC, Frenzke, M, Lampe, J, Hudacek, AW, Springfeld, C et al. (2011). Envelope-chimeric entry-targeted measles virus escapes neutralization and achieves oncolysis. Mol Ther 19: 1813-1820.
-
(2011)
Mol Ther
, vol.19
, pp. 1813-1820
-
-
Miest, T.S.1
Yaiw, K.C.2
Frenzke, M.3
Lampe, J.4
Hudacek, A.W.5
Springfeld, C.6
-
6
-
-
44849140982
-
Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase i clinical trial
-
White, CL, Twigger, KR, Vidal, L, De Bono, JS, Coffey, M, Heinemann, L et al. (2008). Characterization of the adaptive and innate immune response to intravenous oncolytic reovirus (Dearing type 3) during a phase I clinical trial. Gene Ther 15: 911-920.
-
(2008)
Gene Ther
, vol.15
, pp. 911-920
-
-
White, C.L.1
Twigger, K.R.2
Vidal, L.3
De Bono, J.S.4
Coffey, M.5
Heinemann, L.6
-
7
-
-
0036135030
-
Antibody-sensitive and antibodyresistant cell-to-cell spread by vaccinia virus: Role of the A33R protein in antibodyresistant spread
-
Law, M, Hollinshead, R and Smith, GL (2002). Antibody-sensitive and antibodyresistant cell-to-cell spread by vaccinia virus: role of the A33R protein in antibodyresistant spread. J Gen Virol 83(Pt 1): 209-222.
-
(2002)
J Gen Virol
, vol.83
, Issue.PART 1
, pp. 209-222
-
-
Law, M.1
Hollinshead, R.2
Smith, G.L.3
-
8
-
-
0034691508
-
Pre-existent adenovirus antibody inhibits systemic toxicity and antitumor activity of CN706 in the nude mouse LNCaP xenograft model: Implications and proposals for human therapy
-
Chen, Y, Yu, DC, Charlton, D and Henderson, DR (2000). Pre-existent adenovirus antibody inhibits systemic toxicity and antitumor activity of CN706 in the nude mouse LNCaP xenograft model: implications and proposals for human therapy. Hum Gene Ther 11: 1553-1567.
-
(2000)
Hum Gene Ther
, vol.11
, pp. 1553-1567
-
-
Chen, Y.1
Yu, D.C.2
Charlton, D.3
Henderson, D.R.4
-
9
-
-
77955177289
-
Identification of genetically modified maraba virus as an oncolytic rhabdovirus
-
Brun, J, McManus, D, Lefebvre, C, Hu, K, Falls, T, Atkins, H et al. (2010). Identification of genetically modified maraba virus as an oncolytic rhabdovirus. Mol Ther 18: 1440-1449.
-
(2010)
Mol Ther
, vol.18
, pp. 1440-1449
-
-
Brun, J.1
McManus, D.2
Lefebvre, C.3
Hu, K.4
Falls, T.5
Atkins, H.6
-
10
-
-
80054764086
-
Virustumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death
-
Mahoney, DJ, Lefebvre, C, Allan, K, Brun, J, Sanaei, CA, Baird, S et al. (2011). Virustumor interactome screen reveals ER stress response can reprogram resistant cancers for oncolytic virus-triggered caspase-2 cell death. Cancer Cell 20: 443-456.
-
(2011)
Cancer Cell
, vol.20
, pp. 443-456
-
-
Mahoney, D.J.1
Lefebvre, C.2
Allan, K.3
Brun, J.4
Sanaei, C.A.5
Baird, S.6
-
11
-
-
85027956453
-
Thunder and lightning: Immunotherapy and oncolytic viruses collide
-
Melcher, A, Parato, K, Rooney, CM and Bell, JC (2011). Thunder and lightning: immunotherapy and oncolytic viruses collide. Mol Ther 19: 1008-1016.
-
(2011)
Mol Ther
, vol.19
, pp. 1008-1016
-
-
Melcher, A.1
Parato, K.2
Rooney, C.M.3
Bell, J.C.4
-
12
-
-
84855259828
-
Oncolytic viruses: A step into cancer immunotherapy
-
Pol J, Rességuier J and Lichty B (2011). Oncolytic viruses: a step into cancer immunotherapy. Vir Adapt Treat 2012: 1-21.
-
(2011)
Vir Adapt Treat
, vol.2012
, pp. 1-21
-
-
Pol, J.1
Rességuier, J.2
Lichty, B.3
-
13
-
-
77952776857
-
Immunotherapy can reject intracranial tumor cells without damaging the brain despite sharing the target antigen
-
Bridle, BW, Li, J, Jiang, S, Chang, R, Lichty, BD, Bramson, JL et al. (2010). Immunotherapy can reject intracranial tumor cells without damaging the brain despite sharing the target antigen. J Immunol 184: 4269-4275.
-
(2010)
J Immunol
, vol.184
, pp. 4269-4275
-
-
Bridle, B.W.1
Li, J.2
Jiang, S.3
Chang, R.4
Lichty, B.D.5
Bramson, J.L.6
-
14
-
-
84859646663
-
Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma
-
Pulido, J, Kottke, T, Thompson, J, Galivo, F, Wongthida, P, Diaz, RM et al. (2012). Using virally expressed melanoma cDNA libraries to identify tumor-associated antigens that cure melanoma. Nat Biotechnol 30: 337-343.
-
(2012)
Nat Biotechnol
, vol.30
, pp. 337-343
-
-
Pulido, J.1
Kottke, T.2
Thompson, J.3
Galivo, F.4
Wongthida, P.5
Diaz, R.M.6
-
15
-
-
0033929057
-
Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus
-
Stojdl, DF, Lichty, B, Knowles, S, Marius, R, Atkins, H, Sonenberg, N et al. (2000). Exploiting tumor-specific defects in the interferon pathway with a previously unknown oncolytic virus. Nat Med 6: 821-825.
-
(2000)
Nat Med
, vol.6
, pp. 821-825
-
-
Stojdl, D.F.1
Lichty, B.2
Knowles, S.3
Marius, R.4
Atkins, H.5
Sonenberg, N.6
-
16
-
-
70349864985
-
Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus
-
Bridle, BW, Boudreau, JE, Lichty, BD, Brunellière, J, Stephenson, K, Koshy, S et al. (2009). Vesicular stomatitis virus as a novel cancer vaccine vector to prime antitumor immunity amenable to rapid boosting with adenovirus. Mol Ther 17: 1814-1821.
-
(2009)
Mol Ther
, vol.17
, pp. 1814-1821
-
-
Bridle, B.W.1
Boudreau, J.E.2
Lichty, B.D.3
Brunellière, J.4
Stephenson, K.5
Koshy, S.6
-
17
-
-
73949116981
-
Viruses as vaccine vectors for infectious diseases and cancer
-
Draper, SJ and Heeney, JL (2010). Viruses as vaccine vectors for infectious diseases and cancer. Nat Rev Microbiol 8: 62-73.
-
(2010)
Nat Rev Microbiol
, vol.8
, pp. 62-73
-
-
Draper, S.J.1
Heeney, J.L.2
-
18
-
-
34247361532
-
Immunogenicity and safety of a DNA prime/adenovirus boost vaccine against rhesus CEA in nonhuman primates
-
Aurisicchio, L, Mennuni, C, Giannetti, P, Calvaruso, F, Nuzzo, M, Cipriani, B et al. (2007). Immunogenicity and safety of a DNA prime/adenovirus boost vaccine against rhesus CEA in nonhuman primates. Int J Cancer 120: 2290-2300.
-
(2007)
Int J Cancer
, vol.120
, pp. 2290-2300
-
-
Aurisicchio, L.1
Mennuni, C.2
Giannetti, P.3
Calvaruso, F.4
Nuzzo, M.5
Cipriani, B.6
-
19
-
-
30744442807
-
DNA and adenoviral vectors encoding carcinoembryonic antigen fused to immunoenhancing sequences augment antigen-specific immune response and confer tumor protection
-
Facciabene, A, Aurisicchio, L, Elia, L, Palombo, F, Mennuni, C, Ciliberto, G et al. (2006). DNA and adenoviral vectors encoding carcinoembryonic antigen fused to immunoenhancing sequences augment antigen-specific immune response and confer tumor protection. Hum Gene Ther 17: 81-92.
-
(2006)
Hum Gene Ther
, vol.17
, pp. 81-92
-
-
Facciabene, A.1
Aurisicchio, L.2
Elia, L.3
Palombo, F.4
Mennuni, C.5
Ciliberto, G.6
-
20
-
-
26444556446
-
Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA
-
Mennuni, C, Calvaruso, F, Facciabene, A, Aurisicchio, L, Storto, M, Scarselli, E et al. (2005). Efficient induction of T-cell responses to carcinoembryonic antigen by a heterologous prime-boost regimen using DNA and adenovirus vectors carrying a codon usage optimized cDNA. Int J Cancer 117: 444-455.
-
(2005)
Int J Cancer
, vol.117
, pp. 444-455
-
-
Mennuni, C.1
Calvaruso, F.2
Facciabene, A.3
Aurisicchio, L.4
Storto, M.5
Scarselli, E.6
-
21
-
-
79955619094
-
Targeting tumor vasculature with an oncolytic virus
-
Breitbach, CJ, De Silva, NS, Falls, TJ, Aladl, U, Evgin, L, Paterson, J et al. (2011). Targeting tumor vasculature with an oncolytic virus. Mol Ther 19: 886-894.
-
(2011)
Mol Ther
, vol.19
, pp. 886-894
-
-
Breitbach, C.J.1
De Silva, N.S.2
Falls, T.J.3
Aladl, U.4
Evgin, L.5
Paterson, J.6
-
22
-
-
84859438785
-
Treating tumors with a vaccinia virus expressing IFNß illustrates the complex relationships between oncolytic ability and immunogenicity
-
Wang, LC, Lynn, RC, Cheng, G, Alexander, E, Kapoor, V, Moon, EK et al. (2012). Treating tumors with a vaccinia virus expressing IFNß illustrates the complex relationships between oncolytic ability and immunogenicity. Mol Ther 20: 736-748.
-
(2012)
Mol Ther
, vol.20
, pp. 736-748
-
-
Wang, L.C.1
Lynn, R.C.2
Cheng, G.3
Alexander, E.4
Kapoor, V.5
Moon, E.K.6
-
23
-
-
42049104455
-
Virusmediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation
-
Endo, Y, Sakai, R, Ouchi, M, Onimatsu, H, Hioki, M, Kagawa, S et al. (2008). Virusmediated oncolysis induces danger signal and stimulates cytotoxic T-lymphocyte activity via proteasome activator upregulation. Oncogene 27: 2375-2381.
-
(2008)
Oncogene
, vol.27
, pp. 2375-2381
-
-
Endo, Y.1
Sakai, R.2
Ouchi, M.3
Onimatsu, H.4
Hioki, M.5
Kagawa, S.6
-
24
-
-
44449091136
-
Reovirus activates human dendritic cells to promote innate antitumor immunity
-
Errington, F, Steele, L, Prestwich, R, Harrington, KJ, Pandha, HS, Vidal, L et al. (2008). Reovirus activates human dendritic cells to promote innate antitumor immunity. J Immunol 180: 6018-6026.
-
(2008)
J Immunol
, vol.180
, pp. 6018-6026
-
-
Errington, F.1
Steele, L.2
Prestwich, R.3
Harrington, K.J.4
Pandha, H.S.5
Vidal, L.6
-
25
-
-
49749109913
-
Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation
-
Benencia, F, Courrèges, MC, Fraser, NW and Coukos, G (2008). Herpes virus oncolytic therapy reverses tumor immune dysfunction and facilitates tumor antigen presentation. Cancer Biol Ther 7: 1194-1205.
-
(2008)
Cancer Biol Ther
, vol.7
, pp. 1194-1205
-
-
Benencia, F.1
Courrèges, M.C.2
Fraser, N.W.3
Coukos, G.4
-
26
-
-
26844494479
-
HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer
-
Benencia, F, Courrèges, MC, Conejo-García, JR, Mohamed-Hadley, A, Zhang, L, Buckanovich, RJ et al. (2005). HSV oncolytic therapy upregulates interferon-inducible chemokines and recruits immune effector cells in ovarian cancer. Mol Ther 12: 789-802.
-
(2005)
Mol Ther
, vol.12
, pp. 789-802
-
-
Benencia, F.1
Courrèges, M.C.2
Conejo-García, J.R.3
Mohamed-Hadley, A.4
Zhang, L.5
Buckanovich, R.J.6
-
27
-
-
84878621268
-
HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy
-
Bridle, BW, Chen, L, Lemay, CG, Diallo, JS, Pol, J, Nguyen, A et al. (2013). HDAC inhibition suppresses primary immune responses, enhances secondary immune responses, and abrogates autoimmunity during tumor immunotherapy. Mol Ther 21: 887-894.
-
(2013)
Mol Ther
, vol.21
, pp. 887-894
-
-
Bridle, B.W.1
Chen, L.2
Lemay, C.G.3
Diallo, J.S.4
Pol, J.5
Nguyen, A.6
-
28
-
-
1242293633
-
Vaccinationinduced autoimmune vitiligo is a consequence of secondary trauma to the skin
-
Lane, C, Leitch, J, Tan, X, Hadjati, J, Bramson, JL and Wan, Y (2004). Vaccinationinduced autoimmune vitiligo is a consequence of secondary trauma to the skin. Cancer Res 64: 1509-1514.
-
(2004)
Cancer Res
, vol.64
, pp. 1509-1514
-
-
Lane, C.1
Leitch, J.2
Tan, X.3
Hadjati, J.4
Bramson, J.L.5
Wan, Y.6
-
29
-
-
0034981674
-
Development of a FLP/frt system for generating helper-dependent adenoviral vectors
-
Ng, P, Beauchamp, C, Evelegh, C, Parks, R and Graham, FL (2001). Development of a FLP/frt system for generating helper-dependent adenoviral vectors. Mol Ther 3(5 Pt 1): 809-815.
-
(2001)
Mol Ther
, vol.3
, Issue.5 PART 1
, pp. 809-815
-
-
Ng, P.1
Beauchamp, C.2
Evelegh, C.3
Parks, R.4
Graham, F.L.5
-
30
-
-
0029064573
-
Recombinant vesicular stomatitis viruses from DNA
-
Lawson, ND, Stillman, EA, Whitt, MA and Rose, JK (1995). Recombinant vesicular stomatitis viruses from DNA. Proc Natl Acad Sci USA 92: 4477-4481.
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 4477-4481
-
-
Lawson, N.D.1
Stillman, E.A.2
Whitt, M.A.3
Rose, J.K.4
|