Forced activation of notch in macrophages represses tumor growth by upregulating MIR-125a and disabling tumor-associated macrophages

Cancer Research

Volumn 76, Issue 6, 2016, Pages 1403-1415

  Zhao, Jun Long ^a   Huang, Fei ^a   He, Fei ^b   Gao, Chun Chen ^a   Liang, Shi Qian ^a   Ma, Peng Fei ^b   Dong, Guang Ying ^a   Han, Hua ^a,b   Qin, Hong Yan ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; IMMUNOGLOBULIN J RECOMBINATION SIGNAL SEQUENCE BINDING PROTEIN; INTERFERON REGULATORY FACTOR 4; MICRORNA; NOTCH RECEPTOR; NOTCH1 RECEPTOR; PROTEIN MIR 125A; PROTEIN RYBP; PROTEIN SPACA6A; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR YY1; UNCLASSIFIED DRUG; INTERFERON REGULATORY FACTOR; INTERFERON REGULATORY FACTOR-4; MIRN125 MICRORNA, MOUSE; NOTCH1 PROTEIN, MOUSE; REPRESSOR PROTEIN; RYBP PROTEIN, MOUSE; YY1 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER TRANSPLANTATION; CELL DIFFERENTIATION; CONTROLLED STUDY; DOWNSTREAM PROCESSING; GROWTH INHIBITION; INTRON; LEUKOCYTE FUNCTION; MACROPHAGE ACTIVATION; MOUSE; NONHUMAN; PHAGOCYTOSIS; POLARIZATION; POSITIVE FEEDBACK; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR ASSOCIATED LEUKOCYTE; TUMOR MICROENVIRONMENT; UPREGULATION; ANIMAL; C57BL MOUSE; CELL LINE; GENE EXPRESSION REGULATION; GENETICS; MACROPHAGE; PHYSIOLOGY;

ANIMALS; CELL DIFFERENTIATION; CELL LINE; GENE EXPRESSION REGULATION, NEOPLASTIC; INTERFERON REGULATORY FACTORS; MACROPHAGES; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MICRORNAS; RECEPTOR, NOTCH1; REPRESSOR PROTEINS; SIGNAL TRANSDUCTION; UP-REGULATION; YY1 TRANSCRIPTION FACTOR;

EID: 84962109419     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-15-2019     Document Type: Article

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