Hif-1α and Hif-2α differentially regulate Notch signaling through competitive interaction with the intracellular domain of Notch receptors in glioma stem cells

Cancer Letters

Volumn 349, Issue 1, 2014, Pages 67-76

  Hu, Yi Yang ^a   Fu, Luo An ^b   Li, San Zhong ^a,b   Chen, Yan ^a   Li, Jun Chang ^a   Han, Jun ^a   Liang, Liang ^a   Li, Liang ^a,b   Ji, Chen Chen ^a,b   Zheng, Min Hua ^a   Han, Hua ^a  

^a FOURTH MILITARY MEDICAL UNIVERSITY   (China)

^b FOURTH MILITARY MEDICAL UNIVERSITY   (China)

Author keywords

Glioma stem cells; Hif 1 ; Hif 2 ; Hypoxia; Notch

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; HYPOXIA INDUCIBLE FACTOR 2ALPHA; NOTCH RECEPTOR; BASIC HELIX LOOP HELIX TRANSCRIPTION FACTOR; ENDOTHELIAL PAS DOMAIN-CONTAINING PROTEIN 1; HIF1A PROTEIN, HUMAN;

ARTICLE; CANCER STEM CELL; CELL DIFFERENTIATION; CELL HYPOXIA; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; GLIOMA CELL; HUMAN; HUMAN CELL; HUMAN TISSUE; INTRACELLULAR MEMBRANE; MOLECULAR MECHANICS; OXYGEN TENSION; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION; ANIMAL; CELL GROWTH; CHLOROCEBUS AETHIOPS; COS 1 CELL LINE; GENETICS; GLIOMA; HELA CELL LINE; METABOLISM; PHYSIOLOGY; PROTEIN TERTIARY STRUCTURE; STEM CELL; TRANSCRIPTION INITIATION; TUMOR CELL LINE;

ANIMALS; BASIC HELIX-LOOP-HELIX TRANSCRIPTION FACTORS; CELL GROWTH PROCESSES; CELL HYPOXIA; CELL LINE, TUMOR; CERCOPITHECUS AETHIOPS; COS CELLS; GLIOMA; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, NOTCH; SIGNAL TRANSDUCTION; STEM CELLS; TRANSCRIPTIONAL ACTIVATION;

EID: 84900988325     PISSN: 03043835     EISSN: 18727980     Source Type: Journal    
DOI: 10.1016/j.canlet.2014.03.035     Document Type: Article

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