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Volumn 379, Issue 1-2, 2013, Pages 30-34

The role of weight loss and exercise in correcting skeletal muscle mitochondrial abnormalities in obesity, diabetes and aging

Author keywords

Exercise; Mitochondria; Obesity; Physical activity; Skeletal muscle; Weight loss

Indexed keywords

3 HYDROXYACYL COENZYME A DEHYDROGENASE; CYTOCHROME C OXIDASE; INSULIN; LIPID; MITOCHONDRIAL DNA; SUCCINATE DEHYDROGENASE;

EID: 84884530503     PISSN: 03037207     EISSN: 18728057     Source Type: Journal    
DOI: 10.1016/j.mce.2013.06.018     Document Type: Article
Times cited : (63)

References (48)
  • 2
    • 33845514376 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia
    • Asmann Y.W., Stump C.S., Short K.R., Coenen-Schimke J.M., Guo Z., Bigelow M.L., Nair K.S. Skeletal muscle mitochondrial functions, mitochondrial DNA copy numbers, and gene transcript profiles in type 2 diabetic and nondiabetic subjects at equal levels of low or high insulin and euglycemia. Diabetes 2006, 55:3309-3319.
    • (2006) Diabetes , vol.55 , pp. 3309-3319
    • Asmann, Y.W.1    Stump, C.S.2    Short, K.R.3    Coenen-Schimke, J.M.4    Guo, Z.5    Bigelow, M.L.6    Nair, K.S.7
  • 4
    • 65549152185 scopus 로고    scopus 로고
    • Moderate exercise attenuates the loss of skeletal muscle mass that occurs with intentional caloric restriction-induced weight loss in older, overweight to obese adults
    • Chomentowski P., Dube J.J., Amati F., Stefanovic-Racic M., Zhu S., Toledo F.G.S., Goodpaster B.H. Moderate exercise attenuates the loss of skeletal muscle mass that occurs with intentional caloric restriction-induced weight loss in older, overweight to obese adults. J. Gerontol. Ser. A - Biol. Sci. Med. Sci. 2009, 64:575-580.
    • (2009) J. Gerontol. Ser. A - Biol. Sci. Med. Sci. , vol.64 , pp. 575-580
    • Chomentowski, P.1    Dube, J.J.2    Amati, F.3    Stefanovic-Racic, M.4    Zhu, S.5    Toledo, F.G.S.6    Goodpaster, B.H.7
  • 5
    • 79951706196 scopus 로고    scopus 로고
    • Skeletal muscle mitochondria in insulin resistance: differences in intermyofibrillar versus subsarcolemmal subpopulations and relationship to metabolic flexibility
    • Chomentowski P., Coen P.M., Radikova Z., Goodpaster B.H., Toledo F.G. Skeletal muscle mitochondria in insulin resistance: differences in intermyofibrillar versus subsarcolemmal subpopulations and relationship to metabolic flexibility. J. Clin. Endocrinol. Metab. 2011, 96:494-503.
    • (2011) J. Clin. Endocrinol. Metab. , vol.96 , pp. 494-503
    • Chomentowski, P.1    Coen, P.M.2    Radikova, Z.3    Goodpaster, B.H.4    Toledo, F.G.5
  • 8
    • 79954632229 scopus 로고    scopus 로고
    • Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide
    • Dube J.J., Amati F., Toledo F.G., Stefanovic-Racic M., Rossi A., Coen P., Goodpaster B.H. Effects of weight loss and exercise on insulin resistance, and intramyocellular triacylglycerol, diacylglycerol and ceramide. Diabetologia 2011, 54:1147-1156.
    • (2011) Diabetologia , vol.54 , pp. 1147-1156
    • Dube, J.J.1    Amati, F.2    Toledo, F.G.3    Stefanovic-Racic, M.4    Rossi, A.5    Coen, P.6    Goodpaster, B.H.7
  • 11
    • 0035217707 scopus 로고    scopus 로고
    • Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes
    • Goodpaster B.H., He J., Watkins S., Kelley D.E. Skeletal muscle lipid content and insulin resistance: evidence for a paradox in endurance-trained athletes. J. Clin. Endocrinol. Metab. 2001, 86:5755-5761.
    • (2001) J. Clin. Endocrinol. Metab. , vol.86 , pp. 5755-5761
    • Goodpaster, B.H.1    He, J.2    Watkins, S.3    Kelley, D.E.4
  • 13
    • 0035059633 scopus 로고    scopus 로고
    • Large energetic adaptations of elderly muscle to resistance and endurance training
    • Jubrias S.A., Esselman P.C., Price L.B., Cress M.E., Conley K.E. Large energetic adaptations of elderly muscle to resistance and endurance training. J. Appl. Physiol. 2001, 90:1663-1670.
    • (2001) J. Appl. Physiol. , vol.90 , pp. 1663-1670
    • Jubrias, S.A.1    Esselman, P.C.2    Price, L.B.3    Cress, M.E.4    Conley, K.E.5
  • 14
    • 0034076660 scopus 로고    scopus 로고
    • Fuel selection in human skeletal muscle in insulin resistance: a reexamination
    • Kelley D.E., Mandarino L.J. Fuel selection in human skeletal muscle in insulin resistance: a reexamination. Diabetes 2000, 49:677-683.
    • (2000) Diabetes , vol.49 , pp. 677-683
    • Kelley, D.E.1    Mandarino, L.J.2
  • 15
    • 0033400310 scopus 로고    scopus 로고
    • Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss
    • Kelley D.E., Goodpaster B., Wing R.R., Simoneau J.A. Skeletal muscle fatty acid metabolism in association with insulin resistance, obesity, and weight loss. Am. J. Physiol. 1999, 277:E1130.
    • (1999) Am. J. Physiol. , vol.277
    • Kelley, D.E.1    Goodpaster, B.2    Wing, R.R.3    Simoneau, J.A.4
  • 16
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes mellitus
    • Kelley D., He J., Menshikova E., Ritov V. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes mellitus. Diabetes 2002, 51:2944-2950.
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.1    He, J.2    Menshikova, E.3    Ritov, V.4
  • 17
    • 0033308075 scopus 로고    scopus 로고
    • Effect of weight loss on muscle fiber type, fiber size capillarity, and succinate dehydrogenase activity in humans
    • Kern P.A., Simsolo R.B., Fournier M. Effect of weight loss on muscle fiber type, fiber size capillarity, and succinate dehydrogenase activity in humans. J. Clin. Endocrinol. Metab. 1999, 84:4185-4190.
    • (1999) J. Clin. Endocrinol. Metab. , vol.84 , pp. 4185-4190
    • Kern, P.A.1    Simsolo, R.B.2    Fournier, M.3
  • 20
    • 12344305124 scopus 로고    scopus 로고
    • Mitochondrial dysfunction and type 2 diabetes
    • Lowell B.B., Shulman G.I. Mitochondrial dysfunction and type 2 diabetes. Science 2005, 307:384-387.
    • (2005) Science , vol.307 , pp. 384-387
    • Lowell, B.B.1    Shulman, G.I.2
  • 22
    • 0029067962 scopus 로고
    • The mitochondrial carnitine palmitoyl transerase system: its broadening role in fuel homeostasis and new insights into its molecular features
    • McGarry J.D. The mitochondrial carnitine palmitoyl transerase system: its broadening role in fuel homeostasis and new insights into its molecular features. Biochem. Soc. Trans. 1995, 23:321-324.
    • (1995) Biochem. Soc. Trans. , vol.23 , pp. 321-324
    • McGarry, J.D.1
  • 23
    • 77950349827 scopus 로고    scopus 로고
    • Restoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved insulin sensitivity
    • Meex R.C., Schrauwen-Hinderling V.B., Moonen-Kornips E., Schaart G., Mensink M., Phielix E., van de Weijer T., Sels J.P., Schrauwen P., Hesselink M.K. Restoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved insulin sensitivity. Diabetes 2010, 59:572-579.
    • (2010) Diabetes , vol.59 , pp. 572-579
    • Meex, R.C.1    Schrauwen-Hinderling, V.B.2    Moonen-Kornips, E.3    Schaart, G.4    Mensink, M.5    Phielix, E.6    van de Weijer, T.7    Sels, J.P.8    Schrauwen, P.9    Hesselink, M.K.10
  • 27
    • 0018909580 scopus 로고
    • Effect of physical training on skeletal muscle metabolism and ultrastructure in 70 to 75-year-old men
    • Orlander J., Aniansson A. Effect of physical training on skeletal muscle metabolism and ultrastructure in 70 to 75-year-old men. Acta Physiol. Scand. 1980, 109:149-154.
    • (1980) Acta Physiol. Scand. , vol.109 , pp. 149-154
    • Orlander, J.1    Aniansson, A.2
  • 30
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen K.F., Dufour S., Befroy D., Garcia R., Shulman G.I. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N. Engl. J. Med. 2004, 350:664-671.
    • (2004) N. Engl. J. Med. , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 31
    • 77955508579 scopus 로고    scopus 로고
    • Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals
    • Phielix E., Meex R., Moonen-Kornips E., Hesselink M.K., Schrauwen P. Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals. Diabetologia 2010, 53:1714-1721.
    • (2010) Diabetologia , vol.53 , pp. 1714-1721
    • Phielix, E.1    Meex, R.2    Moonen-Kornips, E.3    Hesselink, M.K.4    Schrauwen, P.5
  • 32
    • 78249257768 scopus 로고    scopus 로고
    • Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers
    • Picard M., Ritchie D., Wright K.J., Romestaing C., Thomas M.M., Rowan S.L., Taivassalo T., Hepple R.T. Mitochondrial functional impairment with aging is exaggerated in isolated mitochondria compared to permeabilized myofibers. Aging Cell 2010, 9:1032-1046.
    • (2010) Aging Cell , vol.9 , pp. 1032-1046
    • Picard, M.1    Ritchie, D.2    Wright, K.J.3    Romestaing, C.4    Thomas, M.M.5    Rowan, S.L.6    Taivassalo, T.7    Hepple, R.T.8
  • 35
    • 50549202600 scopus 로고
    • The glucose fatty acid cycle: its role in insulin sensitivity and the metabolic didturbances of diabetes mellitus
    • Randle P.J., Garland P.B., Hales C.N., Newsholme E.A. The glucose fatty acid cycle: its role in insulin sensitivity and the metabolic didturbances of diabetes mellitus. Lancet 1963, 1:785-789.
    • (1963) Lancet , vol.1 , pp. 785-789
    • Randle, P.J.1    Garland, P.B.2    Hales, C.N.3    Newsholme, E.A.4
  • 37
    • 3042821172 scopus 로고    scopus 로고
    • Muscle fat oxidative capacity is not impaired by age but by physical inactivity: association with insulin sensitivity
    • Rimbert V., Boirie Y., Bedu M., Hocquette J.-F., Ritz P., Morio B. Muscle fat oxidative capacity is not impaired by age but by physical inactivity: association with insulin sensitivity. FASEB J. 2004, 18:737-739.
    • (2004) FASEB J. , vol.18 , pp. 737-739
    • Rimbert, V.1    Boirie, Y.2    Bedu, M.3    Hocquette, J.-F.4    Ritz, P.5    Morio, B.6
  • 39
    • 0042266366 scopus 로고    scopus 로고
    • Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity
    • Short K.R., Vittone J.L., Bigelow M.L., Proctor D.N., Rizza R.A., Coenen-Schimke J.M., Nair K.S. Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes 2003, 52:1888-1896.
    • (2003) Diabetes , vol.52 , pp. 1888-1896
    • Short, K.R.1    Vittone, J.L.2    Bigelow, M.L.3    Proctor, D.N.4    Rizza, R.A.5    Coenen-Schimke, J.M.6    Nair, K.S.7
  • 40
    • 0032752951 scopus 로고    scopus 로고
    • Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss
    • Simoneau J.A., Veerkamp J.H., Turcotte L.P., Kelley D.E. Markers of capacity to utilize fatty acids in human skeletal muscle: relation to insulin resistance and obesity and effects of weight loss. FASEB J. 1999, 13:2051-2060.
    • (1999) FASEB J. , vol.13 , pp. 2051-2060
    • Simoneau, J.A.1    Veerkamp, J.H.2    Turcotte, L.P.3    Kelley, D.E.4
  • 41
    • 0038271638 scopus 로고    scopus 로고
    • Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts
    • Stump C.S., Short K.R., Bigelow M.L., Schimke J.M., Nair K.S. Effect of insulin on human skeletal muscle mitochondrial ATP production, protein synthesis, and mRNA transcripts. Proc. Natl. Acad. Sci. USA 2003, 100:7996-8001.
    • (2003) Proc. Natl. Acad. Sci. USA , vol.100 , pp. 7996-8001
    • Stump, C.S.1    Short, K.R.2    Bigelow, M.L.3    Schimke, J.M.4    Nair, K.S.5
  • 42
    • 33747702159 scopus 로고    scopus 로고
    • Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women
    • Toledo F.G., Watkins S., Kelley D.E. Changes induced by physical activity and weight loss in the morphology of intermyofibrillar mitochondria in obese men and women. J. Clin. Endocrinol. Metab. 2006, 91:3224-3227.
    • (2006) J. Clin. Endocrinol. Metab. , vol.91 , pp. 3224-3227
    • Toledo, F.G.1    Watkins, S.2    Kelley, D.E.3
  • 43
    • 34547596186 scopus 로고    scopus 로고
    • Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes
    • Toledo F.G., Menshikova E.V., Ritov V.B., Azuma K., Radikova Z., DeLany J., Kelley D.E. Effects of physical activity and weight loss on skeletal muscle mitochondria and relationship with glucose control in type 2 diabetes. Diabetes 2007, 56:2142-2147.
    • (2007) Diabetes , vol.56 , pp. 2142-2147
    • Toledo, F.G.1    Menshikova, E.V.2    Ritov, V.B.3    Azuma, K.4    Radikova, Z.5    DeLany, J.6    Kelley, D.E.7
  • 44
    • 42449094965 scopus 로고    scopus 로고
    • Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
    • Toledo F.G., Menshikova E.V., Azuma K., Radikova Z., Kelley C.A., Ritov V.B., Kelley D.E. Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes 2008, 57:987-994.
    • (2008) Diabetes , vol.57 , pp. 987-994
    • Toledo, F.G.1    Menshikova, E.V.2    Azuma, K.3    Radikova, Z.4    Kelley, C.A.5    Ritov, V.B.6    Kelley, D.E.7
  • 45
    • 42449094965 scopus 로고    scopus 로고
    • Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content
    • Toledo F.G.S., Menshikova E.V., Azuma K., Radikova Z., Kelley C.A., Ritov V.B., Kelley D.E. Mitochondrial capacity in skeletal muscle is not stimulated by weight loss despite increases in insulin action and decreases in intramyocellular lipid content. Diabetes 2008, 57:987-994.
    • (2008) Diabetes , vol.57 , pp. 987-994
    • Toledo, F.G.S.1    Menshikova, E.V.2    Azuma, K.3    Radikova, Z.4    Kelley, C.A.5    Ritov, V.B.6    Kelley, D.E.7
  • 46
    • 0031417355 scopus 로고    scopus 로고
    • Increased activity of citrate synthase in human skeletal muscle after a single bout of prolonged exercise
    • Tonkonogi M., Harris B., Sahlin K. Increased activity of citrate synthase in human skeletal muscle after a single bout of prolonged exercise. Acta Physiol. Scand. 1997, 161:435-436.
    • (1997) Acta Physiol. Scand. , vol.161 , pp. 435-436
    • Tonkonogi, M.1    Harris, B.2    Sahlin, K.3
  • 47
    • 0037340001 scopus 로고    scopus 로고
    • Skeletal muscle mitochondrial function and lean body mass in healthy exercising elderly
    • Waters D.L., Brooks W.M., Qualls C.R., Baumgartner R.N. Skeletal muscle mitochondrial function and lean body mass in healthy exercising elderly. Mech. Ageing Dev. 2003, 124:301-309.
    • (2003) Mech. Ageing Dev. , vol.124 , pp. 301-309
    • Waters, D.L.1    Brooks, W.M.2    Qualls, C.R.3    Baumgartner, R.N.4
  • 48
    • 73949099327 scopus 로고    scopus 로고
    • Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging
    • Wenz T., Rossi S.G., Rotundo R.L., Spiegelman B.M., Moraes C.T. Increased muscle PGC-1alpha expression protects from sarcopenia and metabolic disease during aging. Proc. Natl. Acad. Sci. USA 2009, 106:20405-20410.
    • (2009) Proc. Natl. Acad. Sci. USA , vol.106 , pp. 20405-20410
    • Wenz, T.1    Rossi, S.G.2    Rotundo, R.L.3    Spiegelman, B.M.4    Moraes, C.T.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.