Suppression of the interferon-mediated innate immune response by pseudorabies virus

Journal of Virology

Volumn 80, Issue 13, 2006, Pages 6345-6356

  Brukman, Alla ^a   Enquist, L W ^a  

^a PRINCETON UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INTERFERON; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; STAT1 PROTEIN;

ANIMAL CELL; ANTIGEN PRESENTATION; ARTICLE; CELL ACTIVATION; CONTROLLED STUDY; EMBRYO; FIBROBLAST; GENE EXPRESSION; HERPES SIMPLEX VIRUS 1; HERPES VIRUS; INFLAMMATION; INNATE IMMUNITY; MICROARRAY ANALYSIS; NATURAL KILLER CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN PHOSPHORYLATION; PSEUDORABIES HERPETOVIRUS; RAT; SIGNAL TRANSDUCTION; UNINDEXED SEQUENCE; VARICELLA ZOSTER VIRUS; VIRION; VIRUS INFECTION;

ANIMALS; ANTIGEN PRESENTATION; ANTIVIRAL AGENTS; CELL LINE; CHICKENPOX; FIBROBLASTS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GENES, MHC CLASS I; HERPES SIMPLEX; HERPESVIRUS 1, HUMAN; HERPESVIRUS 1, SUID; HERPESVIRUS 3, HUMAN; HUMANS; IMMUNE TOLERANCE; INFLAMMATION; INTERFERON-BETA; KILLER CELLS, NATURAL; LYMPHOCYTE ACTIVATION; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PSEUDORABIES; RATS; SIGNAL TRANSDUCTION; STAT1 TRANSCRIPTION FACTOR; SWINE;

HUMAN HERPESVIRUS 1; HUMAN HERPESVIRUS 3; MAMMALIA; SUID HERPESVIRUS 1;

EID: 33745229406     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00554-06     Document Type: Article

References (40)

1. Brierley, M. M., and E. N. Fish. 2005. Stats: multifaceted regulators of transcription. J. Interferon Cytokine Res. 25:733-744.
2. Brittle, E. E., A. E. Reynolds, and L. W. Enquist. 2004. Two modes of pseudorabies virus neuroinvasion and lethality in mice. J. Virol. 78:12951-12963.
3. Cassady, K. A., M. Gross, and B. Roizman. 1998. The herpes simplex virus US11 protein effectively compensates for the gammal(34.5) gene if present before activation of protein kinase R by precluding its phosphorylation and that of the alpha subunit of eukaryotic translation initiation factor 2. J. Virol. 72:8620-8626.
4. Chee, A. V., and B. Roizman. 2004. Herpes simplex virus 1 gene products occlude the interferon signaling pathway at multiple sites. J. Virol. 78:4185-4196.
5. Doughty, L., K. Nguyen, J. Durbin, and C. Biron. 2001. A role for IFN-alpha beta in virus infection-induced sensitization to endotoxin. J. Immunol. 166:2658-2664.
6. Eidson, K. M., W. E. Hobbs, B. J. Manning, P. Carlson, and N. A. DeLuca. 2002. Expression of herpes simplex virus ICP0 inhibits the induction of interferon-stimulated genes by viral infection. J. Virol. 76:2180-2191.
7. Fuchs, W., H. J. Rziha, N. Lukacs, I. Braunschweiger, N. Visser, D. Lutticken, C. S. Schreurs, H. J. Thiel, and T. C. Mettenleiter. 1990. Pseudorabies virus glycoprotein gI: in vitro and in vivo analysis of immunorelevant epitopes. J. Gen. Virol. 71:1141-1151.
8. Ghebrehiwet, B., and E. I. B. Peerschke. 2004. cC1q-R (calreticulin) and gC1q-R/p33: ubiquitously expressed multi-ligand binding cellular proteins involved in inflammation and infection. Mol. Immunol. 41:173-183.
9. Hampl, H., T. Ben-Porat, L. Ehrlicher, K. O. Habermehl, and A. S. Kaplan. 1984. Characterization of the envelope proteins of pseudorabies virus. J. Virol. 52:583-590.
10. Härle, P., V. Cull, M. P. Agbaga, R. Silverman, B. R. G. Williams, C. James, and D. J. J. Carr. 2002. Differential effect of murine alpha/beta interferon transgenes on antagonization of herpes simplex virus type 1 replication. J. Virol. 76:6558-6567.
11. He, B., M. Gross, and B. Roizman. 1997. The gamma(1)34.5 protein of herpes simplex virus 1 complexes with protein phosphatase 1α to dephosphorylate the alpha subunit of the eukaryotic translation initiation factor 2 and preclude the shutoff of protein synthesis by double-stranded RNA-activated protein kinase. Proc. Natl. Acad. Sci. USA 94:843-848.
12. Hengel, H., and U. H. Koszinowski. 1997. Interference with antigen processing by viruses. Curr. Opin. Immunol. 9:470-476.
13. Katze, M. G., Y. He, and M. G. Gale, Jr. 2002. Viruses and interferon: a fight for supremacy. Nat. Rev. Immunol. 2:675-687.
14. Klimstra, W. B., K. D. Ryman, K. A. Bernard, K. B. Nguyen, C. A. Biron, and R. E. Johnston. 1999. Infection of neonatal mice with Sindbis virus results in a systemic inflammatory response syndrome. J. Virol. 73:10387-10398.
15. Levy, D. E., and A. Garcia-Sastre. 2001. The virus battles: IFN induction of the antiviral state and mechanisms of viral evasion. Cytokine Growth Factor Rev. 12:143-156.
16. Levy, D. E., I. Marie, and A. Prakash. 2003. Ringing the interferon alarm: differential regulation of gene expression at the interface between innate and adaptive immunity. Curr. Opin. Immunol. 15:52-58.
17. Lin, R., R. S. Noyce, S. E. Collins, R. D. Everett, and K. L. Mossman. 2004. The herpes simplex virus ICP0 RING finger domain inhibits IRF3- and IRF7-mediated activation of interferon-stimulated genes. J. Virol. 78:1675-1684.
18. McFerran, J. B., and C. Dow. 1975. Studies on immunisation of pigs with the Bartha strain of Aujeszky's disease virus. Res. Vet. Sci. 19:17-22.
19. McGeoch, D. J., and S. Cook. 1994. Molecular phylogeny of the Alphaherpesvirinae subfamily and a proposed evolutionary timescale. J. Mol. Biol. 238:9-22.
20. Mettenleiter, T. C. 2000. Aujeszky's disease (pseudorabies) virus: the virus and molecular pathogenesis-state of the art, June 1999. Vet. Res. 31:99-115.
21. Mossman, K. L., and A. A. Ashkar. 2005. Herpesviruses and the innate immune response. Viral Immunol. 18:267-281.
22. Mossman, K. L., P. F. Macgregor, J. J. Rozmus, A. B. Goryachev, A. M. Edwards, and J. R. Smiley. 2001. Herpes simplex virus triggers and then disarms a host antiviral response. J. Virol. 75:750-758.
23. Ogasawara, K., S. Hida, N. Azimi, Y. Tagaya, T. Sato, T. Yokochi-Fukuda, T. A. Waldmann, T. Taniguchi, and S. Taki. 1998. Requirement for IRF-1 in the microenvironment supporting development of natural killer cells. Nature 391:700-703.
24. Olofsson, P. S., K. Jatta, D. Wagsater, S. Gredmark, U. Hedin, G. Paulsson-Berne, C. Soderberg-Naucler, G. K. Hansson, and A. Sirsjo. 2005. The antiviral cytomegalovirus inducible gene 5/viperin is expressed in atherosclerosis and regulated by proinflammatory agents. Arterioscler. Thromb. Vasc. Biol. 25:e113-e116.
25. Ono, E., S. Watanabe, H. Nikami, T. Tasaki, and H. Kida. 1998. Pseudorabies virus (PRV) early protein 0 activates PRV gene transcription in combination with the immediate-early protein IE180 and enhances the infectivity of PRV genomic DNA. Vet. Microbiol. 63:99-107.
26. Park, C., S. Lee, I. H. Cho, H. K. Lee, D. Kim, S. Y. Choi, S. B. Oh, K. Park, J. S. Kim, and S. J. Lee. 2006. TLR3-mediated signal induces proinflammatory cytokine and chemokine gene expression in astrocytes: differential signaling mechanisms of TLR3-induced IP-10 and IL-8 gene expression. Glia 53:248-256.
27. Parkinson, J., and R. D. Everett. 2000. Alphaherpesvirus proteins related to herpes simplex virus type 1 ICP0 affect cellular structures and proteins. J. Virol. 74:10006-10017.
28. Paulus, C., P. J. Sollars, G. E. Pickard, and L. W. Enquist. 2006. The transcriptome signature of virulent and attenuated pseudorabies virus-infected rodent brain. J. Virol. 80:1773-1786.
29. Platt, K. B., C. J. Mare, and P. N. Hinz. 1979. Differentiation of vaccine strains and field isolates of pseudorabies (Aujeszky's disease) virus: thermal sensitivity and rabbit virulence markers. Arch. Virol. 60:13-23.
30. Pomeranz, L. E., A. E. Reynolds, and C. J. Hengartner. 2005. Molecular biology of pseudorabies virus: impact on neurovirology and veterinary medicine. Microbiol. Mol. Biol. Rev. 69:462-500.
31. Poppers, J., M. Mulvey, D. Khoo, and I. Mohr. 2000. Inhibition of PKR activation by the proline-rich RNA binding domain of the herpes simplex virus type 1 Us11 protein. J. Virol. 74:11215-11221.
32. Rani, M. R., and R. M. Ransohoff. 2005. Alternative and accessory pathways in the regulation of IFN-beta-mediated gene expression. J. Interferon Cytokine Res. 25:788-798.
33. Ray, N., and L. W. Enquist. 2004. Transcriptional response of a common permissive cell type to infection by two diverse alphaherpesviruses. J. Virol. 78:3489-3501.
34. Samuel, C. E. 2001. Antiviral actions of interferons. Clin. Microbiol. Rev. 14:778-809.
35. Sen, G. C. 2001. Viruses and interferons. Annu. Rev. Microbiol. 55:255-281.
36. Takada, A., and Y. Kawaoka. 2003. Antibody-dependent enhancement of viral infection: molecular mechanisms and in vivo implications. Rev. Med. Virol. 13:387-398.
37. Taylor, J. L., S. D. Little, and W. J. O'Brien. 1998. The comparative antiherpes simplex virus effects of human interferons. J. Interferon Cytokine Res. 18:159-165.
38. Vollstedt, S., S. Arnold, C. Schwerdel, M. Franchini, G. Alber, J. P. Di Santo, M. Ackermann, and M. Suter. 2004. Interplay between alpha/beta and gamma interferons with B, and natural killer cells in the defense against herpes simplex virus type 1. J. Virol. 78:3846-3850.
39. Yokota, S., N. Yokosawa, T. Kubota, T. Suzutani, I. Yoshida, S. Miura, K. Jimbow, and N. Fujii. 2001. Herpes simplex virus type 1 suppresses the interferon signaling pathway by inhibiting phosphorylation of STATs and janus kinases during an early infection stage. Virology 286:119-124.
40. Yokota, S., N. Yokosawa, T. Okabayashi, T. Suzutani, S. Miura, K. Jimbow, and N. Fujii. 2004. Induction of suppressor of cytokine signaling 3 by herpes simplex virus type 1 contributes to inhibition of the interferon signaling pathway. J. Virol. 78:6282-6286.